Patents Represented by Attorney, Agent or Law Firm Thomas Hoxie
  • Patent number: 5767378
    Abstract: The present invention provides a method for identifying or selecting from a population of eukaryotic cells cultivated on or in a medium containing at least one compound, cells which have a metabolic advantage as a result of having being transformed, wherein:i) the cells are transformed with a nucleotide sequence or a co-introduced nucleotide sequence one of which comprises a region which: (a) encodes a protein which is involved in the metabolism of the compound, and/or (b) regulates the activity of the protein; andii) the compound is mannose or xylose or a derivative or a precursor of these, or a substrate of the protein, or is capable of being metabolized by the transformed cells into such a substrate, with the proviso that the compound is not mannose when the protein is mannose 6 phosphate isomerase.
    Type: Grant
    Filed: October 3, 1995
    Date of Patent: June 16, 1998
    Assignee: Novartis AG
    Inventors: Kirsten Bojsen, Iain Donaldson, Anna Haldrup, Morten Joersboe, Jette Dina Kreiberg, John Nielsen, Finn Thyge Okkels, Steen Guldager Petersen
  • Patent number: 5731503
    Abstract: An inbred corn line, designated NP 948, is disclosed. The invention relates to the seeds of inbred corn line NP 948, to the plants of inbred corn line NP 948 and to methods for producing a corn plant produced by crossing inbred line NP 948 with itself or with another corn plant. The invention further relates to hybrid corn seeds and plants produced by crossing inbred line NP 948 with another corn line. Particularly the invention provides novel hybrid corn plants, designated N2555 and N3030, produced by crossing inbred NP 948 with another Northrup King proprietary inbred corn line.
    Type: Grant
    Filed: August 22, 1996
    Date of Patent: March 24, 1998
    Assignee: Novartis Corporation
    Inventor: Merl Krier
  • Patent number: 5731500
    Abstract: An inbred maize line, designated CG5NF22. This invention relates to the plants and seeds of inbred maize line CG5NF22 and to methods for producing maize plants by crossing inbred line CG5NF22 with itself or with another maize line. This invention further relates to hybrid maize seeds and plants produced by crossing inbred line CG5NF22 with another maize line.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: March 24, 1998
    Assignee: Novartis Corporation
    Inventor: Louis Reeder
  • Patent number: 5731502
    Abstract: Two inbred maize lines, designated CG5NA58 and CG5NA58A. This invention relates to the plants and seeds of inbred maize lines CG5NA58 and CG5NA58A and to methods for producing maize plants by crossing either inbred line CG5NA58 or CGSNA58A with itself or with another maize line. This invention further relates to hybrid maize seeds and plants produced by crossing either inbred line CG5NA58 or CGSNA58A with another maize line.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: March 24, 1998
    Assignee: Novartis Corporation
    Inventor: Albert R. Hornbrook
  • Patent number: 5731506
    Abstract: According to the invention, there is provided an inbred corn line, designated CG00766. This invention thus relates to the plants and seeds of inbred corn line CG00766 and to methods for producing a corn plant produced by crossing the inbred line CG00766 with itself or with another corn line. This invention further relates to hybrid corn seeds and plants produced by crossing the inbred line CG00766 with another corn line.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: March 24, 1998
    Assignee: Novartis Corporation
    Inventor: Robert L. Miller
  • Patent number: 5731501
    Abstract: An inbred maize line, designated CG4NU15. This invention thus relates to the plants and seeds of inbred maize line CG4NU15 and to methods for producing maize plants by crossing inbred line CG4NU15 with itself or with another maize line. This invention further relates to hybrid maize seeds and plants produced by crossing inbred line CG4NU15 with another maize line.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: March 24, 1998
    Assignee: Novartis Corporation
    Inventor: Duane LeFord
  • Patent number: 5728924
    Abstract: An inbred corn line, designated NP 934, is disclosed. The invention relates to the seeds of inbred corn line NP 934, to the plants of inbred corn line NP 934 and to methods for producing a corn plant produced by crossing inbred line NP 934 with itself or with another corn plant. The invention further relates to hybrid corn seeds and plants produced by crossing inbred line NP 934 with another corn line. Particularly the invention provides a novel hybrid corn plant, designated N7992 produced by crossing inbred NP 934 with another Northrup King proprietary inbred corn line.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: March 17, 1998
    Inventor: Allen R. Henson
  • Patent number: 5728923
    Abstract: An inbred maize line, designated CG3ND97. This invention relates to the plants and seeds of inbred maize line CG3ND97 and to methods for producing maize plants by crossing inbred line CG3ND97 with itself or with another maize line. This invention further relates to hybrid maize seeds and plants produced by crossing inbred line CG3ND97 with another maize line.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: March 17, 1998
    Inventor: Robert Miller
  • Patent number: 5728922
    Abstract: An inbred maize line, designated CG5NA01. This invention relates to the plants and seeds of inbred maize line CG5NA01 and to methods for producing maize plants by crossing inbred line CG5NA01 with itself or with another maize line. This invention further relates to hybrid maize seeds and plants produced by crossing inbred line CG5NA01 with another maize line.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: March 17, 1998
    Assignee: Novartis Corporation
    Inventor: Albert R. Hornbrook
  • Patent number: 5723721
    Abstract: According to the invention, there is provided an inbred corn line, designated CG00685. This invention thus relates to the plants and seeds of inbred corn line CG00685 and to methods for producing a corn plant produced by crossing the inbred line CG00685 with itself or with another corn line. This invention further relates to hybrid corn seeds and plants produced by crossing the inbred line CG00685 with another corn line.
    Type: Grant
    Filed: December 6, 1995
    Date of Patent: March 3, 1998
    Assignee: Novartis Corporation
    Inventor: Christopher P. Clucas
  • Patent number: 5703044
    Abstract: Novel plant proteins (SAFPs) which synergize the activity of antifungal antibiotics are identified. SAFPs are demonstrated to synergize antifungal antibiotics, such as nikkomycins, polyoxins and amphotericins. SAFPs alone also display antifungal activity against several species of fungi, including strains of Candida, Trichoderma, Neurospora and strains of the plant pathogens Fusarium, Rhizoctonia and Chaetomium. Synergistic antifungal compositions containing SAFP and antifungal antibiotics are provided. In particular, synergistic compositions of corn-SAFP (zeamatin), sorghum-SAFP (sormatin) or oat-SAFP (avematin) and nikkomycin are found to be effective as antifungal compositions, especially against the opportunistic human pathogen Candida albicans. Method for employing SAFPs and synergistic compositions containing them for the inhibition of fungi are provided. In addition, a method for purifying SAFP from grain meal is provided.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: December 30, 1997
    Assignee: Novartis Finance Corporation
    Inventors: Walden K. Roberts, Claude P. Selitrennikoff, Bridget E. Laue, Sharon L. Potter