Abstract: A measuring system for use with automated pipettes for determining the presence or absence of a pipette tip. The central conduit of the pipette is connected to a source of pressure waves, such as a speaker and also connected to a pressure wave detector, such as a microphone. Changes in acoustic impedance between an open conduit when no tip is present, a partially constricted conduit when a tip is present, and a closed conduit when the liquid boundary layer is contacted determine the measured states of the apparatus.