Patents Represented by Attorney Timothy E. Torchia, Ph.D

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  • Method for making unclipped HIV envelope protein
    Patent number: 5849533
    Abstract: Methods for making unclipped HIV env proteins are provided. According to the methods, a genetically engineered cell line comprising an nucleic acid sequence encoding an HIV env protein is cultured to produce unclipped HIV env protein, which is recovered from the cell culture.
    Type: Grant
    Filed: February 19, 1997
    Date of Patent: December 15, 1998
    Assignee: Genetech, Inc.
    Inventors: Phillip W. Berman, Brian M. Fendly, Timothy J. Gregory, Elorian M. Wurm
  • Monoclonal antibodies to human leukemia inhibitory factor
    Patent number: 5688681
    Abstract: The invention relates to monoclonal antibodies to human leukemia inhibitory factor. The disclosed monoclonal antibodies are believed to recognize unique epitopes on hLIF and are useful in the treatment of conditions wherein the presence of hLIF causes or contributes to undesirable pathological effects, such as cachexia, dysregulated calcium metabolism, or excessive bone cell proliferation, and in the detection of hLIF, for example, in clinical samples or specimens.
    Type: Grant
    Filed: June 13, 1994
    Date of Patent: November 18, 1997
    Assignee: Genentech, Inc.
    Inventor: Kyung Jin Kim
  • Use of leukemia inhibitory factor specific antibodies and endothelin antagonists for treatment of cardiac hypertrophy
    Patent number: 5573762
    Abstract: A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purpose.
    Type: Grant
    Filed: April 24, 1995
    Date of Patent: November 12, 1996
    Assignee: Genentech, Inc.
    Inventors: Napoleone Ferrara, Kathleen King, Elizabeth Luis, Jennie P. Mather, Nicholas F. Paoni