Abstract: The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
Type:
Grant
Filed:
September 26, 2005
Date of Patent:
July 28, 2009
Assignee:
Janssen Pharmaceutica N.V.
Inventors:
Raymond Ng, Zhihua Sui, Jihua Guan, James C. Lanter, Vernon C. Alford, Jr.
Abstract: The present invention provides a composition for forming a compressed solid dosage form that is a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22. Also included are solid dosage forms made from a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22.
Type:
Grant
Filed:
September 28, 2001
Date of Patent:
September 5, 2006
Assignee:
McNeil-PCC, Inc.
Inventors:
Christopher E. Szymczak, James T. Walter
Abstract: A device for dispensing into a liquid at least one hydrophilic substance deposited thereon including a body having at least one surface area enhancer and at least one hydrophilic substance deposited on the at least one surface area enhancer, to form a coated surface enhancer, and the body. The hydrophilic substance deposited includes a high intensity sweetener, a nutritive sweetener, a flavoring agent, a drug substance, a vitamin, a mineral, and mixtures thereof.
Type:
Grant
Filed:
March 31, 2003
Date of Patent:
November 22, 2005
Assignee:
McNeil-PPC, Inc.
Inventors:
Lee J. Hamiel, Shyhyuan Liao, Thomas E. Sox
Abstract: The present invention is directed to a composition for oral administration that includes chitosan and GMP, wherein the chitosan and GMP are in other than a cationic gum or polysaccharide/protein complex. Also included herein are methods for controlling appetite in humans and animals by orally administering a composition that includes chitosan and GMP, wherein the chitosan and GMP are in other than a cationic gum or polysaccharide/protein complex.
Type:
Grant
Filed:
September 17, 2001
Date of Patent:
September 28, 2004
Assignee:
McNeil-PPC, Inc.
Inventors:
Clemence Dartey, Gilbert Leveille, Thomas E. Sox
Abstract: The present invention provides a sterol, stanol or their corresponding acid ester in a form suitable for the manufacture of an oral dosage form. A method for producing the oral dosage form is also provided.
Type:
Grant
Filed:
September 2, 1998
Date of Patent:
April 23, 2002
Assignee:
McNeil-PPC, Inc.
Inventors:
Richard D. Bruce, John D. Higgins, Stephen A. Martellucci