Patents Represented by Attorney Timothy J. Keane

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  • Synthetic urogastrone gene, corresponding plasmid recombinants, transformed cells, production thereof and urgastrone expression
    Patent number: 4719180
    Abstract: A synthetic gene characterised in that it codes for the expression of urogastrone or a sub-unit thereof is disclosed.The production thereof by the assembly and ligation of a number of nucleotide blocks is also disclosed, as are corresponding plasmid recombinants, transformed cells and the production thereof.The expression of urogastrone is further disclosed.Urogastrone is a polypeptide hormore (protein) which may be isolated in small amounts from human urine. It has an application in the treatment of ulcers and in the promotion of wound healing. The present invention provides a more viable commercial production.
    Type: Grant
    Filed: September 13, 1984
    Date of Patent: January 12, 1988
    Assignee: G. D. Searle & Co.
    Inventors: Michael A. W. Eaton, Michael T. Doel, Norman H. Carey, John C. Smith, David M. J. Lilley, Leslie D. Bell
  • Bicyclo-substituted phenylacetonitrile derivatives
    Patent number: 4681970
    Abstract: The invention relates to compounds of the formula: ##STR1## which are useful cardiovascular agents.
    Type: Grant
    Filed: March 21, 1986
    Date of Patent: July 21, 1987
    Assignee: G. D. Searle & Co.
    Inventor: Chi-Dean Liang