Patents Represented by Attorney, Agent or Law Firm Todd L. Juneau
  • Small molecule carbamate or urea hair growth compositions and uses
    Patent number: 6194440
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule carbamates and ureas.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 27, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Small molecule pipecolic acid derivative hair growth compositions and uses
    Patent number: 6191125
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 20, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Sulfone hair growth compositions and uses
    Patent number: 6187796
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule sulfonamides.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Pipecolic acid derivative hair growth compositions and uses
    Patent number: 6187784
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-linked ureas and carbamates of heterocyclic thioesters
    Patent number: 6184243
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: February 6, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li, Wei Huang
  • Pyrrolidine derivative hair growth compositions and uses
    Patent number: 6177455
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pyrrolidine derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: January 23, 2001
    Assignee: Gpi Nil Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-oxide of heterocyclic ester, amide, thioester, or ketone hair growth compositions and uses
    Patent number: 6172087
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-oxides of heterocyclic esters, amides, thioesters, or ketones.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: January 9, 2001
    Assignee: GPI NIL Holding, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Naaladase inhibitors
    Patent number: 5968915
    Abstract: The present disclosure relates to dipeptidase inhibitors, and more particularly, to N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme inhibitors which are proposed as novel agents for the treatment of prostate cancer. NAALADase is enzyme which is a membrane-bound metalloprotease which hydrolyzes the dipeptide, N-acetyl-L-aspartate-L-glutamate (NAAG) to yield glutamate and N-acetylaspartate. The compounds of the present invention include phosphinic acid derivatives that inhibit NAALADase enzyme activity and which have been found useful for inhibiting the growth of prostate cancer cells.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: October 19, 1999
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Paul F. Jackson, Barbara S. Slusher
  • Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth
    Patent number: 5696135
    Abstract: This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
    Type: Grant
    Filed: May 28, 1996
    Date of Patent: December 9, 1997
    Assignees: GPI NIL Holdings, Inc., Johns Hopkins Univ. School of Medicines
    Inventors: Joseph P. Steiner, Solomon Snyder, Gregory S. Hamilton
  • Certain phosphonomethyl-pentanedioic acid derivatives thereof
    Patent number: 5672592
    Abstract: The present disclosure relates to dipeptidase inhibitors, and more particularly, to N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme inhibitors which are proposed as novel agents for the treatment of prostate cancer. NAALADase is enzyme which is a membrane-bound metalloprotease which hydrolyzes the dipeptide, N-acetyl-L-aspartate-L-glutamate (NAAG) to yield glutamate and N-acetylaspartate. The compounds of the present invention include phosphinic acid derivatives that inhibit NAALADase enzyme activity and which have been found useful for inhibiting the growth of prostate cancer cells.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: September 30, 1997
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Paul F. Jackson, Barbara S. Slusher