Patents Represented by Attorney, Agent or Law Firm Tom Brody
  • Regulatory T cells; methods
    Patent number: 6746670
    Abstract: Methods for increasing yields of Tr1 cells, useful, e.g., in transplantation contexts. Use of interferon and IL-15 are described.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: June 8, 2004
    Assignee: Schering Corporation
    Inventors: Megan K. Levings, Rene de Waal Malefyt, Maria Grazia Roncarolo
  • Nucleic acids encoding CTLA-8; and related reagents
    Patent number: 6706870
    Abstract: CTLA-8 antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: March 16, 2004
    Assignees: Inserm, Institut National de la Sante et de la Recherche Medicale, Schering Corporation
    Inventors: Pierre Golstein, Eric Rouvier, Francois Fossiez, Serge J. E. Lebecque, Odile Djossou, Jacques Banchereau
  • Nucleic acids encoding mammalian interleukin-1&zgr;, related reagents and methods
    Patent number: 6680380
    Abstract: Nucleic acids encoding mammalian, e.g., primate, IL-1&zgr;, purified IL-1&zgr; polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: January 20, 2004
    Assignee: Schering Corporation
    Inventor: Jacqueline C. Timans
  • Methods of modulating IL-174 response
    Patent number: 6676939
    Abstract: Agonists or antagonists of cytokine designated IL-174, and various methods of their use are provided. In particular, the methods make use of facts that many activities of the IL-174 cytokine are described.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: January 13, 2004
    Assignee: Schering Corporation
    Inventors: Stephen D. Hurst, Sandra M. Zurawski, Donna M. Rennick
  • Regulatory T cells; methods
    Patent number: 6670146
    Abstract: Methods for increasing yields of regulatory T cells, useful, e.g., in transplantation contexts. Use of antigen presenting cells and anti-CD28 are also described.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: December 30, 2003
    Assignee: Schering Corporation
    Inventors: Franck J. Barrat, Pieter Andre Boonstra, Huub Savelkoul, Rene de Waal Malefyt, Anne O'Garra
  • Mammalian proteases; related reagents
    Patent number: 6638507
    Abstract: Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: October 28, 2003
    Assignee: Schering Corporation
    Inventors: Sriram Balasubramanian, John Ford, Daniel M. Gorman, Gerard Zurawski
  • Polynucleotides encoding DIRS1
    Patent number: 6586228
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: July 1, 2003
    Assignee: Schering Corporation
    Inventors: Christi L. Parham, Kevin W. Moore, Nicholas J. Murgolo
  • IL-17-like cytokine binding compounds and antibodies
    Patent number: 6562578
    Abstract: IL-17-like cytokines from mammals, reagents and diagnostic kits related thereto including purified proteins, specific antibodies, and nucleic acids are provided. Methods of using the reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: May 13, 2003
    Assignee: Schering Corporation
    Inventors: Daniel M. Gorman, J. Fernando Bazan, Robert A. Kastelein
  • Mammalian proteinases; oxidoreductases; related reagents
    Patent number: 6518405
    Abstract: Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: February 11, 2003
    Assignee: Schering Corporation
    Inventors: Lynette M. Dowling, Constance F. Huffine, Daniel M. Gorman
  • Antibodies that specifically bind DNAX leukocyte associated immunoglobulin-like receptor
    Patent number: 6479638
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using reagents relating to nucleic acids encoding monocyte cell proteins, and diagnostic kits, are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: November 12, 2002
    Assignee: Schering Corporation
    Inventors: Gosse Jan Adema, Linde Meyaard, Daniel M. Gorman, Terrill K. McClanahan, Sandra M. Zurawski, Gerard Zurawski, Lewis L. Lanier, Joseph H. Phillips, Jr.
  • Lymphotactin uses
    Patent number: 6395268
    Abstract: This invention relates to the use of lymphotactin or lymphotactin antagonists for administration to an animal. The administration of these therapeutic entities will attract certain cell types, or can be blocked to prevent such attraction. It also provides means to protect stem cells.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: May 28, 2002
    Assignee: Schering Corporation
    Inventors: Joseph A. Hedrick, Susan A. Hudak, Donna M. Rennick, Albert Zlotnik
  • Pyramid chest
    Patent number: D467096
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: December 17, 2002
    Inventor: Giorgio DiCostanzo