Patents Represented by Attorney Toni-Junell Herbert
  • Patent number: 8318483
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: November 27, 2012
    Assignee: Advanced Technologies and Regenerative Medicine, LLC
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian Ross Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Anna Gosiewska
  • Patent number: 8318736
    Abstract: HIV replication inhibitors of formula wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and X have specific definitions, and pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds and compositions.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: November 27, 2012
    Assignee: Janssen R&D Ireland
    Inventors: Jerôme Emile Georges Guillemont, Céline Isabelle Mordant, Benoit Antoine Schmitt
  • Patent number: 8313920
    Abstract: A method of screening a compound which modulates dipeptidyl peptidase I (DPPI) activities comprises the steps of adding a peptide substrate of DPPI to a reaction mixture which comprises DPPI and a compound, wherein the peptide substrate of DPPI has at least 3 amino acids and binds to a binding site of DPPI in addition to the S1-S2 site; and measuring the molecular weight of the substrate, wherein a change in the molecular weight of the substrate is indicative of the presence of DPPI activity.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: November 20, 2012
    Assignee: Janssen Research & Development, LLC
    Inventors: Matthew Olson, Matthew Todd
  • Patent number: 8277796
    Abstract: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: October 2, 2012
    Assignee: Advanced Technologies and Regenerative Medicine, LLC
    Inventors: Darin J. Messina, Sanjay Mistry, Alexander M. Harmon, Ian Ross Harris, Anthony J. Kihm, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Patent number: 8268885
    Abstract: The present invention relates to small molecules as entry inhibitors of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors with other anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: September 18, 2012
    Assignee: Janssen R&D Ireland
    Inventors: Koenraad Lodewijk August Van Acker, Piet Tom Bert Paul Wigerinck, Lieve Emma Jan Michiels, Abdellah Tahri
  • Patent number: 5712033
    Abstract: Asphalt/polymer fibers include, by weight, 30% to 85% polymeric material and 15% to 70% asphaltic material, where the polymeric material has a melt flow index of no more than about 35 grams/10 minutes. Preferably, the combination of polymeric material and asphaltic material has a melt flow index of from 80 grams/10 minutes to 800 grams/10 minutes. The asphaltic material is preferably asphalt having a softening point of from C. to C. The polymeric material is preferably a polymer selected from polypropylene, polyethylene, polystyrene, polyesters, ethylene copolymers, acrylates, methacrylates, and mixtures of these polymers. The organic fibers of asphalt/polymer may be intermingled with mineral reinforcing fibers and formed into products such as mats.
    Type: Grant
    Filed: August 5, 1996
    Date of Patent: January 27, 1998
    Assignee: Owens-Corning Fiberglass Technology, Inc.
    Inventors: Kevin P. Gallagher, Donn R. Vermilion