Abstract: A device for performing active compression/decompression cardiopulmonary resuscitation includes an applicator body with an upper surface and a lower surface. The lower surface includes provisions for detachably securing to the patient's chest, such as a vacuum cup or an adhesive layer. For manual resuscitation, the upper surface will include a strap or other structure for securing a performer's hand thereto. In an exemplary device, a disc-shaped handle is attached to the upper surface of a vacuum cup applicator by a short connecting stem structure. A pressure gauge mounted to the handle permits the performer to monitor how much force is being applied in both the compression and decompression phases. For automatic applications, a mechanical drive member will be secured to the upper surface. By alternately pressing and lifting on the applicator device, the patient's chest can be compressed and expanded to improve induced ventilation and circulation.