Patents Represented by Attorney, Agent or Law Firm Townsend and Townsend and Crew LLP
  • Patent number: 7887812
    Abstract: Targeted disruption of the centrin gene leads to attenuation of growth in Leishmania. Preferred embodiments of the invention provide attenuated strains of Leishmania useful for the preparation of immunogenic preparations including vaccines against a disease caused by infection with a virulent Leishmania strain and as tools for the generation of immunological and diagnostic reagents. Other preferred embodiments provide related immunogenic compositions, methods of generating an immune response, methods for producing a vaccine, and methods of forming attenuated strains of Leishmania.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: February 15, 2011
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Hira L. Nakhasi, Angamuthu Selvapandiyan, Alain Debrabant, Robert C. Duncan, Poonam Salotra, Gannavaram Sreenivas
  • Patent number: 7884182
    Abstract: The invention provides a method of assembling oligopeptide intermediates in a native chemical ligation reaction that eliminates self-ligation of bi-functional intermediates. An important aspect of the invention is a bi-functional intermediate with an N-terminal heterocyclic protecting group which effectively prevents self-ligation in the chemical assembly process. The present invention is useful in methods for convergent synthesis of polypeptides and proteins and improves the efficiency of native chemical ligation reactions, particularly where three or more peptide fragments are used to assemble a polypeptide or protein product.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: February 8, 2011
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Paolo Botti, Hubert Gaertner, Sonia Manganiello, Matteo Villain
  • Patent number: 7884955
    Abstract: Techniques for performing one or more actions based upon physical locations of one or more paper documents. According to an embodiment of the present invention, the paper documents have identification tags physically associated with them. The physical locations of the paper documents are determined based upon information read from the identification tags physically associated with the paper documents. One or more actions are performed based upon the physical locations of the paper documents.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: February 8, 2011
    Assignee: Ricoh Company, Ltd.
    Inventors: Jonathan J. Hull, Jamey Graham, Dar-Shyang Lee
  • Patent number: 7883206
    Abstract: Embodiments of the present invention relate to a multifocal lens having a mostly spherical power region and a progressive optical power region. Embodiments of the present invention provide for the proper alignment and positioning of each of these regions, the amount of optical power provided by each of the regions, the optical design of the progressive optical power region, and the size and shape of each of the regions. The combination of these design parameters allows for an optical design having less unwanted astigmatism and distortion as well as both a wider channel width and a shorter channel length compared to conventional PALs. Embodiments of the present invention may also provide a new, inventive far-intermediate distance zone and may further provide for increased vertical stability of vision within a zone of the lens.
    Type: Grant
    Filed: December 25, 2007
    Date of Patent: February 8, 2011
    Assignee: PixelOptics, Inc.
    Inventors: Ronald D. Blum, William Kokonaski, Venkatramani S. Iyer, Joshua N. Haddock, Mark Mattison-Shupnick
  • Patent number: 7885830
    Abstract: Insurance policy deductibles are managed by a plurality of interrelated tables each including a plurality of variables. The variables in a first table include a geographical variable, a transaction variable and an effective policy date variable. The variables in another table include additional geographic variables, structural characteristics, amount of insurance and provides controls for managing deductibles. The variables in a further table distinguish deductibles available to the policies. In an additional table, the variables identify movement from an old deductible to a new deductible.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: February 8, 2011
    Assignee: United Services Automobile Association
    Inventors: Jerromy Laverne Johnson, Michael Hongming Chan
  • Patent number: 7885139
    Abstract: A multi-chip package includes a plurality of memory chips and a control chip, wherein the control chip stores information about whether the memory chips are operating normally and selects chips that are operating normally according to an address signal.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: February 8, 2011
    Assignee: Hynix Semiconductor Inc.
    Inventors: Je Il Ryu, You Sung Kim
  • Patent number: 7884826
    Abstract: Methods and apparatus are disclosure for maintaining realistic grooming of simulated objects. In a method for simulating objects, a reference shape associated with a simulated object is received. A predetermined orientation is also received. A force acting on the simulated object is then modified based on the predetermined orientation. The force acts on the simulated object to shape the simulated object according to the reference shape. The force may be “strategically weakened” when the simulated object (or a portion thereof) is substantially aligned with the predetermined orientation. In a further method for simulating objects, a measured height associated with the simulated object is received. A “lifting” force is generated to reduce a difference between the measured height and a predetermined height associated with the reference shape. The lifting force simulates structure and internal forces that provide volume and shaping to physical objects, such as hair.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: February 8, 2011
    Assignee: Pixar
    Inventor: David Baraff
  • Patent number: 7884831
    Abstract: Circuits, methods, and apparatus that provide texture caches and related circuits that store and retrieve texels in a fast and efficient manner. One such texture circuit provides an increased number of bilerps for each pixel in a group of pixels, particularly when trilinear or aniso filtering is needed. For trilinear filtering, texels in a first and second level of detail are retrieved for a number of pixels during a clock cycle. When aniso filtering is performed, multiple bilerps can be retrieved for each of a number of pixels during one clock cycle.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: February 8, 2011
    Assignee: NVIDIA Corporation
    Inventors: Alexander L. Minkin, Joel J. McCormack, Paul S. Heckbert, Michael J. M. Toksvig, Luke Y. Chang, Karim Abdalla, Bo Hong, John W. Berendsen, Walter Donavan, Emmett M. Kilgariff
  • Patent number: 7882841
    Abstract: Methods and systems for resecting and debulking prostatic tissue to utilize a shaft carrying an energy source. The shaft is anchored by a balloon or other structure expanded in the bladder, and the energy source is capable of directing ablative energy radially outwardly from the urethra, where the energy source will be moved in order to remove a pre-defined volume of prostatic tissue.
    Type: Grant
    Filed: January 2, 2008
    Date of Patent: February 8, 2011
    Assignee: Procept Corporation
    Inventors: Nikolai Aljuri, Rodney C. Perkins
  • Patent number: 7885922
    Abstract: A method of processing data includes identifying a capture redo byte address, initiating a capture process at the capture redo byte address, creating a clone of a source database to a logical change number, and initiating an apply process at a target database.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: February 8, 2011
    Assignee: Oracle International Corporation
    Inventors: Alok Pareek, Eric Ian Fish
  • Patent number: 7885160
    Abstract: There is provided an information recording and reproducing method and an apparatus for the same capable of optimizing the shift adjustment of a recording pulse recorded in an optical disk even at the time of recording information on the optical disk at a high speed. The shift adjustment value of the recording pulse optimized at a low speed recording on an optical disk is multiplied by a constant value to be taken as the optimum shift conditions of the recording pulse at the high speed recording.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: February 8, 2011
    Assignees: Hitachi, Ltd., Hitachi-LG Data Storage, Inc.
    Inventors: Takakiyo Yasukawa, Koichi Watanabe, Naohito Ikeda, Toshio Shoji, Yasuhiro Wada
  • Patent number: 7883520
    Abstract: Corneal epithelial pocket formation systems include a cutting head and a blade coupled to the cutting head. The blade is coupled to the cutting head at an orientation that is effective in maintaining a viable separated pocket defining portion of corneal epithelium of an eye of a patient during formation of a corneal epithelial pocket of the eye. The blade includes a cutting edge surface at its distal end. The cutting edge surface is effective in separating the corneal epithelium from the underlying Bowman's membrane of the eye without leaving residual corneal epithelial cells in contact with Bowman's membrane that may result in corneal epithelial cell growth between a corneal implant located in the corneal epithelial pocket and the underlying Bowman's membrane. Versions of the present systems include spring loaded blade holders, which may be removable from the cutting head. Versions also can include applanators.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: February 8, 2011
    Assignee: ForSight Labs, LLC
    Inventors: Markus Gaeckle, Helmut Maas, Daniel Wolf, Tanja Riehl
  • Patent number: 7885454
    Abstract: A computer-implemented method for generating depth-of-field effects includes receiving information specifying an input image rendered using a pinhole camera. A first set of circles of confusion associated with portions of the input image are determined based a set of parameters associated with the pinhole camera. The first set of circles of confusion are then associated with heat conductivity of a medium. The portions of the input image are blurred according to heat diffusion in the medium to generate a first output image having a first depth-of-field effect.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: February 8, 2011
    Assignee: Pixar
    Inventor: Michael Kass
  • Patent number: 7884992
    Abstract: A photochromic optical article comprises a substrate, and a photochromic coating coated on an outer surface of the substrate and having at least two photochromic layers. Each of the photochromic layers has a composition that contains a carrier and at least one photochromic dye. The compositions of the photochromic layers are different from each other.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: February 8, 2011
    Assignee: Darwin Optical Co., Ltd.
    Inventors: Yun-Cheng Wang, Yi-Tang Wang
  • Patent number: 7883669
    Abstract: Systems for managing workflows to perform chemical or biological reactions using microfluidic devices.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: February 8, 2011
    Assignee: Fluidigm Corporation
    Inventors: Gang Sun, Greg Harris, Andy May, Kyle Self, Kevin Farrell, Paul Wyatt
  • Patent number: 7885298
    Abstract: A system for producing frequency converted light includes a first seed laser operable to provide a first laser signal and a second seed laser operable to provide a second laser signal. The system also includes an optical combiner optically coupled to the first seed laser and the second seed laser. The optical combiner is operative to combine the first laser signal and the second laser signal into a combined laser signal. The system further includes a power amplifier optically coupled to the optical combiner. An intensity of both the first laser signal and the second laser signal are increased by the power amplifier. The system additionally includes a harmonic converter optically coupled to the power amplifier.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: February 8, 2011
    Assignee: Deep Photonics Corporation
    Inventor: Michael J. Munroe
  • Patent number: 7883019
    Abstract: An integrated circuit (IC) includes a high capacitance solid state circuit region configured to perform predetermined operations, a RFID block comprising a FeRAM block for storing data, and an interface unit configured to transfer to the RFID block an externally-provided unique ID for wirelessly identifying the IC, the unique ID being stored in the FeRAM block. The IC further includes a conductive trace extending through predetermined regions of the IC, the conductive trace being configured as an antenna for the RFID block, wherein the RFID block is configured to receive and transmit information to an external source via the antenna.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: February 8, 2011
    Assignee: Hynix Semiconductor Inc.
    Inventors: Hee-Bok Kang, Jin-Hong Ahn
  • Patent number: 7883965
    Abstract: A semiconductor device includes a device isolation structure, a recess channel structure, and a gate electrode. The device isolation structure is formed in a semiconductor substrate to define an active region. The recess channel structure is disposed in the semiconductor substrate under the active region. The gate electrode includes a holding layer disposed in a gate region to fill the recess channel structure. The holding layer prevents a seam and a shift of the seam occurring in the recess channel structure.
    Type: Grant
    Filed: December 30, 2006
    Date of Patent: February 8, 2011
    Assignee: Hynix Semiconductor Inc.
    Inventors: Shin Gyu Choi, Seung Chul Oh
  • Patent number: 7885434
    Abstract: At least one wrong template for storing features of pattern information imaged on condition unsuitable for biometric authentication is provided and the wrong template information is collated with collation template information produced by extracting features from biometric information when authentication information is registered. When similarity is low, the collation template information is stored in an authentication template. The collation template is collated with the wrong template upon authentication and when similarity is high, authentication processing is not made. Further, when similarity of the collation template information and the wrong template information is high, a guidance message for solving a problem is displayed to the user. Thus, reduction of authentication performance is prevented.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: February 8, 2011
    Assignee: Hitachi, Ltd.
    Inventors: Keiji Kitane, Yasushi Aoyama, Harumi Satou, Shuichi Uchiyama
  • Patent number: D632415
    Type: Grant
    Filed: June 13, 2009
    Date of Patent: February 8, 2011
    Assignee: Stion Corporation
    Inventors: Frank Yang, Robert Wieting