Abstract: A system for providing franking services includes one or more networks, one or more postage meters, and a postal infrastructure data center connected to the one or more meters through the one or more networks, wherein the postal infrastructure data center establishes communication with the one or more meters as required.

Abstract: A programmable processor and method for improving the performance of processors by expanding at least two source operands, or a source and a result operand, to a width greater than the width of either the general purpose register or the data path width. The present invention provides operands which are substantially larger than the data path width of the processor by using the contents of a general purpose register to specify a memory address at which a plurality of data path widths of data can be read or written, as well as the size and shape of the operand. In addition, several instructions and apparatus for implementing these instructions are described which obtain performance advantages if the operands are not limited to the width and accessible number of general purpose registers.

Abstract: A piezoelectric layer is formed of a plurality of ferroelectric films containing lead (Pb), zirconium (Zr), and titanium (Ti) above a first electrode. A boundary portion between a first ferroelectric film closest to the first electrode and a second ferroelectric film formed above the first ferroelectric film has an area where the maximum value of a concentration of titanium with respect to zirconium is 80% or more.

Abstract: The present invention relates to methods of treating intermittent claudication comprising administering glucagon-like peptide-1 (GLP-1) molecules to subjects suffering therefrom.

Abstract: Targeted disruption of the centrin gene leads to attenuation of growth in Leishmania. Preferred embodiments of the invention provide attenuated strains of Leishmania useful for the preparation of immunogenic preparations including vaccines against a disease caused by infection with a virulent Leishmania strain and as tools for the generation of immunological and diagnostic reagents. Other preferred embodiments provide related immunogenic compositions, methods of generating an immune response, methods for producing a vaccine, and methods of forming attenuated strains of Leishmania.

Abstract: A method for opening a portion of a passageway of a patient is disclosed. The patient has a first metallic structure attached to a portion of the patient's neck. The method includes obtaining a second magnetic structure, placing the second magnetic structure proximate the first metallic structure attached to the portion of the patient's neck, and pulling the second magnetic structure away from the patient's neck to thereby open the passageway.

Abstract: Systems for managing workflows to perform chemical or biological reactions using microfluidic devices.

Abstract: A computer-implemented method for generating depth-of-field effects includes receiving information specifying an input image rendered using a pinhole camera. A first set of circles of confusion associated with portions of the input image are determined based a set of parameters associated with the pinhole camera. The first set of circles of confusion are then associated with heat conductivity of a medium. The portions of the input image are blurred according to heat diffusion in the medium to generate a first output image having a first depth-of-field effect.

Abstract: Corneal epithelial pocket formation systems include a cutting head and a blade coupled to the cutting head. The blade is coupled to the cutting head at an orientation that is effective in maintaining a viable separated pocket defining portion of corneal epithelium of an eye of a patient during formation of a corneal epithelial pocket of the eye. The blade includes a cutting edge surface at its distal end. The cutting edge surface is effective in separating the corneal epithelium from the underlying Bowman's membrane of the eye without leaving residual corneal epithelial cells in contact with Bowman's membrane that may result in corneal epithelial cell growth between a corneal implant located in the corneal epithelial pocket and the underlying Bowman's membrane. Versions of the present systems include spring loaded blade holders, which may be removable from the cutting head. Versions also can include applanators.

Abstract: A semiconductor device includes a device isolation structure, a recess channel structure, and a gate electrode. The device isolation structure is formed in a semiconductor substrate to define an active region. The recess channel structure is disposed in the semiconductor substrate under the active region. The gate electrode includes a holding layer disposed in a gate region to fill the recess channel structure. The holding layer prevents a seam and a shift of the seam occurring in the recess channel structure.

Abstract: At least one wrong template for storing features of pattern information imaged on condition unsuitable for biometric authentication is provided and the wrong template information is collated with collation template information produced by extracting features from biometric information when authentication information is registered. When similarity is low, the collation template information is stored in an authentication template. The collation template is collated with the wrong template upon authentication and when similarity is high, authentication processing is not made. Further, when similarity of the collation template information and the wrong template information is high, a guidance message for solving a problem is displayed to the user. Thus, reduction of authentication performance is prevented.

Abstract: The invention provides a method of assembling oligopeptide intermediates in a native chemical ligation reaction that eliminates self-ligation of bi-functional intermediates. An important aspect of the invention is a bi-functional intermediate with an N-terminal heterocyclic protecting group which effectively prevents self-ligation in the chemical assembly process. The present invention is useful in methods for convergent synthesis of polypeptides and proteins and improves the efficiency of native chemical ligation reactions, particularly where three or more peptide fragments are used to assemble a polypeptide or protein product.

Abstract: Occluding structures may be created within a body lumen by advancing a length of material distally through the body lumen. By drawing a distal location on the advanced length of material in a proximal direction, the material may be compacted into a structure which at least partially occludes the lumen. The occluding structure may be used to remove kidney stones from the ureter in conjunction with lithotripsy and irrigation.

Abstract: Provided is a method of operating a flash memory device having a first area and a second area, in which a programmed state and an erased state of the first area are opposite to that of the second area. The method includes receiving a program command, inverting the program data when the received program command is a command for programming the second area, and programming the inverted program data into the second area.

Abstract: Insurance policy deductibles are managed by a plurality of interrelated tables each including a plurality of variables. The variables in a first table include a geographical variable, a transaction variable and an effective policy date variable. The variables in another table include additional geographic variables, structural characteristics, amount of insurance and provides controls for managing deductibles. The variables in a further table distinguish deductibles available to the policies. In an additional table, the variables identify movement from an old deductible to a new deductible.

Abstract: A system for producing frequency converted light includes a first seed laser operable to provide a first laser signal and a second seed laser operable to provide a second laser signal. The system also includes an optical combiner optically coupled to the first seed laser and the second seed laser. The optical combiner is operative to combine the first laser signal and the second laser signal into a combined laser signal. The system further includes a power amplifier optically coupled to the optical combiner. An intensity of both the first laser signal and the second laser signal are increased by the power amplifier. The system additionally includes a harmonic converter optically coupled to the power amplifier.

Abstract: An audit planning system enables users to plan effective audits by identifying audit units having potentially large impacts and risks on an enterprise and enabling users to select audit units to include in audits based on a variety of different criteria. The audit planning system displays the audit units of the enterprise and a visual indicator of the impact and risk associated with each audit unit. The audit planning system enables users to select the displayed audit units to plan an audit. The audit planning system may display audit units in an impacted financial statement, a tree map, a graph, and/or a table. The audit planning system may sort and/or display audit units with visual indicators specifying associated risks, impacts, materiality values, exposures, coverages, and/or audit costs. The audit planning system can further display visual indications of the changes in audit units' associated attributes over time.

Abstract: A method for managing Unlicensed Mobile Access (UMA) communications within a local area network and a LAN-based UMA network controller are disclosed. The method includes monitoring packets received from a first UMA device connected to the local area network and detecting whether they represent a call between the first UMA device and a second UMA device. The method also includes determining whether the second UMA device is connected to the local area network. If the packets represent a call between the first and second UMA devices and the second UMA device is connected to the local area network, packets representing audio data are maintained within the local area network.

Abstract: Aspects of the present invention provide multifocal lenses having one or more multifocal inserts comprising one or more diffractive regions. A diffractive region of a multifocal insert of the present invention can provide a constant optical power or can provide a progression of optical power, or any combination thereof. A multifocal insert of the present invention can be fabricated from any type of material and can be inserted into any type of bulk lens material. A diffractive region of a multifocal insert of the present invention can be positioned to be in optical communication with one or more optical regions of a host lens to provide a combined desired optical power in one or more vision zones. Index matching layers of the present invention can be used to reduce reflection losses at interfaces of the host lens and multifocal insert.

Abstract: A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.