Patents Represented by Law Firm Townsend and Townsende and Crew
  • Method for detecting immune dysfunction in asymptomatic aids patients and for predicting organ transplant rejection
    Patent number: 5514556
    Abstract: A sensitive and accurate tissue culture system and kit fop detecting subtle changes in immune function is provided. The system is based on the comparison of IL-2 production by T helper cells in response to recall antigens including influenza A virus, tatanus toxoid, alloantigens, mouse xenogeneic antigens and the like or combinations thereof. Different stages of immune dysfunction can be differentiated and organ graft rejection can be predicted by the method of the present invention.
    Type: Grant
    Filed: January 19, 1994
    Date of Patent: May 7, 1996
    Assignee: The United States of America as represented by The Department of Health and Human Services
    Inventors: Gene M. Shearer, Mario Clerici, Charles S. Via