Patents Represented by Attorney Townsend & Townsend & Crew
  • Patent number: 7622138
    Abstract: The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of a pharmaceutically active agent and to methods for treating or preventing or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions. One particular type of condition for which the pharmaceutical compositions are useful is a microbial infection, e.g., of the skin, ear, or eye, especially for veterinary applications.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: November 24, 2009
    Assignee: TDEXX Laboratories
    Inventor: Yerramilli V. S. N. Murthy
  • Patent number: 7618651
    Abstract: The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of a pharmaceutically active agent and to methods for treating or preventing or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions. One particular type of condition for which the pharmaceutical compositions are useful is a microbial infection, e.g., of the skin, ear, or eye, especially for veterinary applications.
    Type: Grant
    Filed: June 24, 2004
    Date of Patent: November 17, 2009
    Assignee: IDEXX Laboratories
    Inventor: Yerramilli V. S. N. Murthy
  • Patent number: 7550625
    Abstract: The invention relates to compounds of formula (I): wherein R is —C(O)CH2OCH2CH2OCH3 or —C(O)CH2N(CH3)2. The invention also relates to pharmaceutical compositions comprising a compound formula (I) and methods of treating or preventing a condition in an animal comprising administering to an animal in need thereof a compound of formula (I).
    Type: Grant
    Filed: October 13, 2008
    Date of Patent: June 23, 2009
    Assignee: IDEXX Laboratories
    Inventor: Yerramilli V. S. N. Murthy
  • Patent number: 7439268
    Abstract: The present invention provides compositions and methods for administering florfenicol to mammals. The compositions contain a prodrug of florfenicol in a pharmaceutically acceptable carrier. In one embodiment the prodrug is an esterized form of florfenicol. Examples of suitable prodrugs include one or a combination of one or a combination of the following: florfenicol acetate, florfenicol propionate, florfenicol butyrate, florfenicol pentanoate, florfenicol hexanoate, florfenicol heptanoate, florfenicol octanoate, florfenicol nanoate, florfenicol decanoate, florfenicol undecanoate, florfenicol dodecanoate, and florfenicol phthalate. In another embodiment the prodrug is converted into the florfenicol in vivo by the action of one or more endogenous esterases. The invention also provides new compounds, pharmaceutical compositions containing the compounds, and methods for their administration.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: October 21, 2008
    Assignee: Idexx Laboratories
    Inventors: Yerramilli V. S. N. Murthy, Robert H. Suva
  • Patent number: 7369822
    Abstract: A novel transmitter circuit is disclosed for receiving of an input signal and for providing of an amplitude increased RF output signal. Pluralities of switching power amplifiers are disposed along two signal propagating circuit branches and utilized for increasing a magnitude of the input signal, to form an output signal, which is a magnitude increased version of the input signal. Each of the switching power amplifiers utilizes switching elements having various magnitude increasing capacity and coupled to a control circuit for each being switchably selectable for providing of the magnitude increase to the input signal.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: May 6, 2008
    Assignee: SiGe Semiconductor Inc.
    Inventors: Jeremy Loraine, Jeffery Wojtiuk, Philip Macphall
  • Patent number: 7266568
    Abstract: A method of storing information for recorded information and a source document is provided. The method comprises: determining a first piece of information included in the recorded information; determining at least a first source document from one or more source documents that comprises information that matches the first piece of information; and storing information identifying the recorded information, information representative of the first piece of information, and information identifying the first source document such that the information identifying the first source document can be determined given the information identifying the recorded information and the information representative of the first piece of information.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: September 4, 2007
    Assignee: Ricoh Company, Ltd.
    Inventors: Berna Erol, Jonathan Hull, Dar-Shyang Lee
  • Patent number: 7256171
    Abstract: This invention provides compounds and methods for treating inflammation. The compounds modulate the core 2 oligosaccharide-mediated binding of inflammatory cells, such as neutrophils, to endothelial cells and other myeloid cells. Significantly, the of the invention methods block inflammation without affecting lymphocyte trafficking. In some embodiments, the compounds inhibit the activity of a core 2 GlcNAc transferase that is involved in synthesizing the core 2 oligosaccharides.
    Type: Grant
    Filed: November 20, 1999
    Date of Patent: August 14, 2007
    Assignee: The Regents of the University of California
    Inventors: Jamey D. Marth, Lesliey G. Ellies
  • Patent number: 7070657
    Abstract: This invention provides a stable process for depositing an antireflective layer. Helium gas is used to lower the deposition rate of plasma-enhanced silane oxide, silane oxynitride, and silane nitride processes. Helium is also used to stabilize the process, so that different films can be deposited. The invention also provides conditions under which process parameters can be controlled to produce antireflective layers with varying optimum refractive index, absorptive index, and thickness for obtaining the desired optical behavior.
    Type: Grant
    Filed: October 15, 1999
    Date of Patent: July 4, 2006
    Assignee: Applied Materials Inc.
    Inventors: David Cheung, Joe Feng, Judy H. Huang, Wai-Fan Yau
  • Patent number: 7070780
    Abstract: Compositions and methods are provided for the treatment of demyelinating autoimmune disease. Therapeutic doses are administered of an ordered peptide comprising a repeated motif {SEQ ID NO: 1} [1E2Y3Y4K]n, where n is from 2 to 6. Some specific peptides of interest include those having the sequence {SEQ ID NO:4} EYYKEYYKEYYK. The peptide may consist only of the ordered repeats, or may be extended at either termini by the addition of other amino acid residues. For therapy, the peptides may be administered topically or parenterally, e.g. by injection at a particular site, including subcutaneously, intraperitoneally, intravascularly, or the like or transdermally, as by electrotransport. In a preferred embodiment, subcutaneous injection is used to deliver the peptide. The subject methods are used for prophylactic or therapeutic purposes. The compositions of the invention may also contain other therapeutically active agents, e.g. immunosuppressants, ?-interferon, steroids, etc.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: July 4, 2006
    Assignee: Board of Trustees of the Leland Stanford Junior University
    Inventors: Lawrence Steinman, Pedro Jose Ruiz
  • Patent number: 7049200
    Abstract: A method of forming a sidewall spacer on a gate electrode of a metal oxide semiconductor device that includes striking a first plasma to form an oxide layer on a side of the gate electrode, where the first plasma is generated from a oxide gas that includes O3 and bis-(tertiarybutylamine)silane, and striking a second plasma to form a carbon-doped nitride layer on the oxide layer, where the second plasma may be generated from a nitride gas that includes NH3 and the bis-(tertiarybutylamine)silane. The first and second plasmas may be formed using plasma CVD and the bis-(tertiarybutylamine)silane flows uninterrupted between the striking of the first plasma and the striking of the second plasma.
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: May 23, 2006
    Assignee: Applied Materials Inc.
    Inventors: Reza Arghavani, Ken MacWilliams, Hichem M'Saad
  • Patent number: 7036453
    Abstract: A method is provided for depositing a thin film on a substrate in a process chamber with reduced incidence of plasma charge damage. A process gas containing a precursor gases suitable for forming a plasma is flowed into a process chamber, and a plasma is generated from the process gas to deposit the thin film on the substrate. The precursor gases are flowed into the process chamber such that the thin film is deposited at the center of the substrate more rapidly than at an edge of the substrate.
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: May 2, 2006
    Assignee: Applied Materials, Inc.
    Inventors: Tetsuya Ishikawa, Alexandros T. Demos, Seon-Mee Cho, Feng Gao, Kaveh F. Niazi, Michio Aruga
  • Patent number: 7004107
    Abstract: A substrate processing system that includes a deposition chamber having a reaction zone, a substrate holder that positions a substrate in the reaction zone, a gas distribution system that includes a gas inlet manifold for supplying one or more process gases to said reaction zone, a plasma power source for forming a plasma from a process gas introduced into the reaction zone of the deposition chamber and an impedance monitor that is electrically coupled to the deposition chamber to measure an impedance level of the plasma. In a preferred embodiment, the substrate holder is a first electrode and the gas inlet manifold is a second electrode and RF power is supplied by the plasma power source to either the first or second electrodes to form the plasma.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: February 28, 2006
    Assignee: Applied Materials Inc.
    Inventors: Sébastien Raoux, Mandar Mudholkar, William N. Taylor
  • Patent number: 6956105
    Abstract: The present invention provides nucleic acid and protein sequences for a novel Th-1 cell-specific protein, Chandra. The herein-disclosed sequences can be used for any of a number of purposes, including for the specific detection of Th1 lymphocytes, for the identification of molecules that associate with and/or modulate the activity of Chandra, to diagnose any of a number of conditions associated with Th1 or Th2 cell activity, or to modulate the number and/or activity of Th1 or Th2 lymphocytes in a mammal.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: October 18, 2005
    Assignee: Amgen Inc.
    Inventors: Ulrike Schindler, Chandrasekar Venkataraman
  • Patent number: 6951972
    Abstract: The disclosed discovery relates to the functioning of the Ac-Ds transposon system in small grain cereals such as barley, wheat, and oat. Methods and compositions for using this system for introducing recombinant expression cassettes and transposon tagging of genes in small grain cereals are provided.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: October 4, 2005
    Assignee: The Regents of the University of California
    Inventors: Peggy Lemaux, David McElroy, Thomas Koprek
  • Patent number: 6946368
    Abstract: A germanium substrate is positioned in a process chamber. A plasma is generated from a treatment gas that includes a flow of a hydrogen-containing gas. The plasma is provided to the process chamber to react with GeO2 in the germanium substrate.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: September 20, 2005
    Assignee: Applied Materials, Inc.
    Inventors: Laurent Vandroux, Hervé Monchoix
  • Patent number: 6943091
    Abstract: A deposition method for filling recesses in a substrate is described. In the method, the substrate is exposed to an energized deposition gas comprising first and second components, to deposit a first layer of a material in the recess, and thereafter, the ratio of the first component to the second component is reduced, to deposit a second layer of the material over the first layer in the recess. The deposition method may be used to fill recesses in a substrate and smoothen out reentrant cavities in a silicon nitride liner, in the fabrication of polysilicon gates in a substrate.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: September 13, 2005
    Assignee: Applied Materials, Inc.
    Inventors: Hung-Tien Yu, Yiwen Chen
  • Patent number: 6939808
    Abstract: A method for etching a metal layer formed on a substrate to form a metal line, using an amorphous carbon layer as a pattern mask. One embodiment of the method of the invention etches a metal layer formed on a substrate, for forming a metal line, by depositing an amorphous carbon layer on the metal layer, patterning the amorphous carbon layer to provide a pattern mask on the metal layer, thus exposing portions of said metal layer; and etching the exposed portions of the metal layer, to form a metal line. In an embodiment, the metal layer comprises a copper layer.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: September 6, 2005
    Assignee: Applied Materials, Inc.
    Inventors: Eugene Tzou, Jie Yuan, Yan Ye
  • Patent number: 6936042
    Abstract: This invention provides surgical tools or instruments for use in minimally invasive telesurgical applications. The instruments typically include a base whereby the instrument is removably mountable on a robotically controlled articulated arm. An elongate shaft extends from the base. A working end of the shaft is disposed at an end of the shaft remote from the base. A wrist member is pivotally mounted on the working end. At least one end effector element mounting formation is pivotally mounted on an opposed end of the wrist member. A plurality of elongate elements, e.g., cables, extend from the end effector element mounting formation and the wrist member to cause selective angular displacement of the wrist member and end effector mounting formation in response to selective pulling of the elongate elements.
    Type: Grant
    Filed: April 16, 2002
    Date of Patent: August 30, 2005
    Assignee: Intuitive Surgical
    Inventors: Daniel T. Wallace, Christopher A. Julian, Tracey A. Morley, David S. Baron
  • Patent number: 6933695
    Abstract: The present invention generally relates to surgical devices, systems, and methods, especially for minimally invasive surgery, and more particularly provides structures and techniques for aligning a robotic surgery system with a desired surgical site. The present invention describes techniques for mounting, configuring and arranging set-up arms for the surgical manipulators and endoscope drive mechanisms of a telesurgical system within an operating theater. The various aspects of the invention improve and optimize space utilization in the conduct of a surgical procedure, especially in the telesurgical systems which provide for concurrent operation by two surgeons using multiple robotic arm assemblies. In one aspect, the invention includes a method and apparatus for ceiling-height mounting of surgical set-up arms, and in another aspect, the invention includes a method and apparatus for the mounting of surgical setup arms to the table pedestal or floor below an operating table.
    Type: Grant
    Filed: April 21, 2004
    Date of Patent: August 23, 2005
    Assignee: Intuitive Surgical
    Inventor: Stephen J. Blumenkranz
  • Patent number: 6913652
    Abstract: A system for processing substrates includes a first process chamber configured to perform a given process on a first substrate. A second process chamber is configured to perform the same process as the first chamber on a second substrate. A gas source system is configured to output a process gas. A gas flow system includes a flow channel coupled to the gas source system and the first and second process chambers to provide the process gas into the first and second process chambers. The gas source system further includes a gas flow controller to regulate flow rates of the process gas provided into the first and second chambers in order to provide the first and second substrates with substantially uniform process results.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: July 5, 2005
    Assignee: Applied Materials, Inc.
    Inventor: Hongqing Shan