Patents Represented by Attorney Tyler M. Dylan

Find this attorney in the Justia Lawyer Directory

  • Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens
    Patent number: 5712087
    Abstract: Combinations of HCV antigens that have a broader range of immunological reactivity than any single HCV antigen. The combinations consist of an antigen from the C domain of the HCV polyprotein, and at least one additional HCV antigen from either the NS3 domain, the NS4 domain, the S domain, or the NS5 domain, and are in the form of a fusion protein, a simple physical mixture, or the individual antigens commonly bound to a solid matrix.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: January 27, 1998
    Assignee: Chiron Corporation
    Inventors: Michael Houghton, Qui-Lim Choo, George Kuo
  • Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
    Patent number: 5683864
    Abstract: Combinations of HCV antigens that have a broader range of immunological reactivity than any single HCV antigen. The combinations consist of an antigen from the C domain of the HCV polyprotein, and at least one additional HCV antigen from either the NS3 domain, the NS4 domain, the S domain, or the NS5 domain, and are in the form of a fusion protein, a simple physical mixture, or the individual antigens commonly bound to a solid matrix.
    Type: Grant
    Filed: July 7, 1992
    Date of Patent: November 4, 1997
    Assignee: Chiron Corporation
    Inventors: Michael Houghton, Qui-Lim Choo, George Kuo
  • Modified N-4 nucleotides for use in amplified nucleic acid hybridization assays
    Patent number: 5594118
    Abstract: Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.
    Type: Grant
    Filed: May 10, 1995
    Date of Patent: January 14, 1997
    Assignee: Chiron Corporation
    Inventors: Michael S. Urdea, Thomas Horn