Abstract: A method for validating or calibrating a chemical detector at a point of use. The method includes presenting a device to the chemical detector, the device comprising a frangible container defining a predetermined volume and a chemical material sealed within the frangible container in a predetermined amount, and breaking the frangible container to release the chemical material for detection by the chemical detector. A device and method of making the device for validating or calibrating a chemical at a point of use are also provided.

Abstract: A water sampling device and method for use with a radiation probe. The device includes a base, filtrate reservoir, filter media support disc, and sample reservoir. The sample reservoir may be interchanged with a radiation probe adaptor. The device and method provide a simple and convenient means to separate particulate solids from a water sample prior to measuring radioactivity without the need for a heat source or electrical power to evaporate the water. The device and method can be used with a variety of commercially available radiation probes and is suitable for field applications.

Abstract: A system and method to safely dispose of hazardous liquid waste includes a glove box for conducting a test with a hazardous liquid material therein, the glove box having a drainage line connected to a waste tank for directing the hazardous liquid waste from the glove box to the waste tank. A waste disposal line and an air vent line are connected between the waste tank and a waste container. Double-valved connectors are positioned in the waste disposal line and in the air vent line allowing the liquid waste and air to flow between the waste tank and a waste container when the double-valved connectors are coupled together. When the double-valved connectors are uncoupled, both the waste tank and the waste container are completely sealed to the surrounding environment.

Abstract: The invention relates to methods and products enabling decontamination of chemical warfare agents and/or toxic industrial chemicals. More particularly, the invention pertains to improvements of surface decontamination processes using novel sorbents such as nanotubular titania.

Abstract: An improved system for collecting, detecting, and classifying submicron-sized particles in a sample comprising an Integrated Virus Detection System (IVDS) of the type wherein the detecting means includes a differential mobility analyzer (DMA) and condensation particle counter (CPC), the improvement comprising positioning an aerosol collector or an electrostatic collector between the differential mobility analyzer and the condensation particle counter wherein submicron-sized particles from the environmental sample are collected for further analysis.

Abstract: A flow modulator to control the flow of an aerosol to an aerosol detection and/or monitoring system and other aerosol flow systems includes a chamber having an inlet and an outlet, a diverging section of the chamber beneath the inlet that has a flow divider at the center to divide the aerosol into fractions, a recirculation section in which the divided aerosol fractions are recombined, and a converging section that channels the recombined aerosol fractions to the outlet of the chamber.

Abstract: A chemical warfare (CW) agent decontamination system and method for decontaminated surfaces contaminated by CW agents. The system includes both solid particles and liquid solution in admixture such that the solid particles absorb the liquid decontamination material. The method of decontaminating surfaces contaminated with CW agents includes contacting the CW agent with a sufficient amount of a solid-particle sorbent for a sufficient time and under conditions which are sufficient to produce a reaction product having less toxicity than the CW agent. CW agents to be decontaminated include the nerve agents VX and G-type agents, and mustard agent HD. The system is non-toxic and has a reduced environmental impact as compared to the previously available decontamination systems and solutions.

Abstract: The present invention relates to mechanical devices and methods allowing the safe removal of heavy, difficult to handle fragments from an explosive destruction system (EDS).

Abstract: A process is provided for identifying a cell type in a sample that includes identification of one or more peptide sequences in the sample. Each peptide sequence is assigned to a protein of known sequence. A matrix of assignments is generated for the presence or absence of each peptide in one or more cells. The matrix of assignments is rearranged according to cell classification. A cell type based on the most probable cell classification is identified.

Abstract: A launchable grenade system is backwards compatible with conventional launch platforms and is capable of launching a variety of payloads at greater range and increased launch velocity, and with significantly improved targeting accuracy. The grenade is pre-packaged in a disposable launch canister that effectively confines launch ejection gases behind the projectile until it exits the canister. Additional enhancements in one or more embodiments, include collapsible aerodynamic stabilizers that are folded inside the launch canister prior to firing and deploy in flight to improve projectile stability and ballistic performance; electronic fuzing for improved repeatability and targeting precision, next-generation digital capabilities that include electronic device identification, failsafe and device monitoring; and momentum arresting forward expulsion of the payload to reduce blunt trauma hazard from projectile hardware and to provide for short distance targeting at significantly greater speed.

Abstract: A residual life indicator for determining the residual life of a filter has a first sample filter with an inlet coupleable to an inlet of the filter whose residual life is to be determined, a second sample filter having an inlet coupleable to an outlet of the filter whose residual life is to be determined, a chemical tracer source selectively coupled to the inlets of the first and second sample filters, and a detector selectively coupled to outlets of the first and second filters.

Abstract: A vapor generator safety relief device for use in a surety system includes a conical flask, manifold, bubbler, and relief valve. The manifold includes a first chamber for inlet gas and a second chamber for outlet gas. The first chamber comprises an inlet port, an inlet tube, and a relief valve housing. The second chamber comprises an outlet tube and an outlet port. The bubbler is confluent with the inlet tube and disposed within the flask.

Abstract: A method for detecting ribosome inactivating protein (RIP) activity in a sample is provided that involves contacting a sample that contains an RIP with an inventive substrate that is depurinated to form product. The product is hybridized to a template and cleaved by an apurinic/apyrimidinic endonuclease such that releasing the blocked 3? end only in a sample that contains RIP activity. The 5? end of the product serves as a primer for extension by a polymerase reaction. The newly synthesized strand complementary to the template is detected by RT-PCR processes. A kit is provided suitable for field or laboratory use.

Abstract: An aerosol generator includes a saturator having an enclosure for passing a gas therethrough, and a porous substrate being adapted for retaining a non-vaporized form of an aerosol material, wherein the porous substrate is further adapted to release a vaporized form of the aerosol material for introduction into the gas within the enclosure, and a condenser adapted for receiving the gas containing the vapor from the saturator to produce an aerosol containing the aerosol material.

Abstract: The present invention is generally related to products and methods that facilitate the use of Venezuelan equine encephalitis (VEE) virus TC-83 (TC-83) as a non-hazardous simulant, or surrogate, for viable pathogenic viruses. Specifically, TC-83 nucleic sequences are used in a method of detecting VEE or TC-83 in a sample thought to contain a biological threat agent. TC-83 and its nucleic acid sequence may therefore be used in the research, development, testing, evaluation, and training for technologies that enable the detection of biological threat agents. More particularly, specific primers and probes may be used to verify that instruments and systems using PCR detection methods are functioning properly.

Abstract: A device for use with a detection means and a solvent source for sampling low volatility hazardous chemicals within a sample matrix is comprised of a sonicator having a probe for providing mechanical agitation to the sample matrix; means for transporting solvent gas from the solvent source to the sample matrix; means for transporting sample gas from the sample matrix to the detection means; and a heating element for heating the sample gas, solvent gas, and sample matrix. The device may include a thermocouple for providing a temperature reading. It also may include a plurality of interchangeable probe tips of different shapes.

Abstract: An optomechanical switching device, a control system, and a graphical user interface for a photopolarimetric lidar standoff detection that employs differential-absorption Mueller matrix spectroscopy. An output train of alternate continuous-wave CO2 laser beams [ . . . L1:L2 . . . ] is directed onto a suspect chemical-biological (CB) aerosol plume or the land mass it contaminates (S) vis-à-vis the OSD, with L1 [L2] tuned on [detuned off] a resonant molecular absorption moiety of CB analyte. Both incident beams and their backscattered radiances from S are polarization-modulated synchronously so as to produce gated temporal voltage waveforms (scattergrams) recorded on a focus at the receiver end of a sensor (lidar) system. All 16 elements of the Mueller matrix (Mij) of S are measured via digital or analog filtration of constituent frequency components in these running scattergram data streams (phase-sensitive detection).

Abstract: A quantitative fit test (QNFT) system and method for assessing the biological fit factor (FF) performance of respiratory protective devices. The biological QNFT system includes the following three main elements: an aerosol generation system; an exposure chamber; and an aerosol sampling subsystem. The aerosol sampling subsystem includes an aerosol spectrometer that counts particles in discrete size units ranging from 0.5 to 20 micrometers (?m) making it possible to obtain several size-specific FF measurements from a single respirator fit test. A virtual impactor in the aerosol generation system increases the number of challenge particles in the primary target size of interest (1 to 5 ?m) and increases the sensitivity of the method allowing FF values of up to one million to be measured without the need to correct for in-mask background particles.

Abstract: A concentrator device and method of concentrating a liquid sample may be provided. The concentrator device may include a pressure vessel and a filter element disposed within the pressure vessel. The pressure vessel may include an inlet configured to introduce pressurized air into a first portion of the pressure vessel and a first outlet fluidly coupled with a second portion of the pressure vessel. The first outlet may be adapted to be selectively opened and closed. A second outlet may be configured to receive a capillary tube inserted into the first portion of the pressure vessel. The filter element may be configured to receive a liquid sample to be concentrated. The filter element may substantially separate the first portion of the pressure vessel from the second portion of the pressure vessel and may define a retentate side adjacent to the first portion and a filtrate side adjacent to the second portion.

Abstract: A rapid and sensitive method to measure endonuclease activity comprising reacting a substrate suspected of having endonuclease activity with a synthetic nucleotide to induce endonuclease cleavage of the synthetic nucleotide followed by measurement of activity by carrying out a polymerase chain reaction (PCR). When no polymerase chain reaction takes place when carrying out the method it is indicative of no endonuclease activity in the substrate. Synthetic oligonucleotides, primers, and probes useful for carrying out the method are disclosed.