Abstract: The invention provides materials and methods for making anisotropic solids which may be in the form of films, layers, shaped elements, and other shaped articles. The methods provide anisotropic solids without the need for rolling, rubbing, or stretching to impart orientational alignment of the molecules of the solid. The methods employ organic or organometallic compounds which are soluble orienting molecules. The solvent or solvent system must be sufficiently volatile to be removed without disruption of the molecular orientation. The soluble orienting molecules include those containing one or more hydrophilic and/or ionic groups and the solvent or solvent system can be a polar organic solvent or solvent system or an aqueous solvent or solvent system. The invention also provides novel compounds having quaterrylene, perylene and naphthalene ring systems carrying one or more hydrophilic and/or ionic groups.

Abstract: In particular embodiments, the present disclosure provides targets including a metal layer and defining a hollow inner surface. The hollow inner surface has an internal apex. The distance between at least two opposing points of the internal apex is less than about 15 ?m. In particular examples, the distance is less than about 1 ?m. Particular implementations of the targets are free standing. The targets have a number of disclosed shaped, including cones, pyramids, hemispheres, and capped structures. The present disclosure also provides arrays of such targets. Also provided are methods of forming targets, such as the disclosed targets, using lithographic techniques, such as photolithographic techniques. In particular examples, a target mold is formed from a silicon wafer and then one or more sides of the mold are coated with a target material, such as one or more metals.

Abstract: Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals against Bacillus anthracis or other capsulated pathogens. The methods include administering a capsular polypeptide of a pathogen of interest and a CD40 agonist to a human or animal. The capsular polypeptide or the CD40 agonist is administered in such an amount or frequency that an immunoprotective response can be elicited in the human or animal against the pathogen of interest. In another aspect, the present invention provides methods of using passive immunization with anti-capsular polypeptide antibodies to prevent or treat infections caused by Bacillus anthracis or other pathogens. In yet another aspect, the present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum or other biological samples.

Abstract: Locations of the origins of the photons are acquired from a scanned sample with reference to a scan frame. The location on the sample from which a photon was emitted is inferred from the location of the scan as commanded by a scan drive signal, a feedback signal related to the position of the scan device, or alternatively by the point in time during a scan at which the photon is detected. A position function, e.g., photon probability density, is associated with a photon position. Summing or other processing of photon probability density functions can require fewer photons to converge to an ideal density distribution associated with an image feature than are required using conventional pixel binning. Stored data can be mapped into pixels or voxels of a display or otherwise processed. Original data remains available in the digital storage for post-hoc analysis. Imprecision introduced by the display process need not adversely affect the precision of the collected data.

Abstract: Apparatus and methods are disclosed for amplifying an energy beam such as a beam of laser light or a charged particle beam. An exemplary method includes providing a liner having a first end, a second end, a liner axis, and a lumen extending along the liner axis and being bound by interior reflective walls of the liner. An energy beam is introduced into the first end of the liner. The beam propagates through the lumen from the first end to the second end as the beam reflects multiple times from the interior walls of the liner. Meanwhile, an implosive force is applied to the liner. The implosive force compresses the interior walls implosively toward the liner axis in a manner that amplifies the beam as the beam propagates through the lumen of the imploding liner. The amplified energy beam can be used for any of various purposes including ignition of a fusion target.

Abstract: A control method and system for controlling a hydraulically actuated mechanical arm to perform a task, the mechanical arm optionally being a hydraulically actuated excavator arm. The method can include determining a dynamic model of the motion of the hydraulic arm for each hydraulic arm link by relating the input signal vector for each respective link to the output signal vector for the same link. Also the method can include determining an error signal for each link as the weighted sum of the differences between a measured position and a reference position and between the time derivatives of the measured position and the time derivatives of the reference position for each respective link. The weights used in the determination of the error signal can be determined from the constant coefficients of the dynamic model. The error signal can be applied in a closed negative feedback control loop to diminish or eliminate the error signal for each respective link.

Abstract: Values for one or more particle properties, such as an aerosol asymmetry parameter g, can be measured directly using a detector that measures scattered light. The detector can comprise two or more diffusers coupled to optical sensors responsive to scattered light that is incident on the surfaces of the diffusers. One or more weighing functions can be obtained based on diffuser geometry. In an example, the diffusers correspond to quadrants of a circular toroid.

Abstract: In certain aspects, the present disclosure provides a monitoring device that includes a condensation unit and a detector, such as a proportional detector. The condensation unit includes a condensation surface, a cooler abutting the condensation surface, and a collection vessel in fluid communication with the condensation surface. The monitoring device may include a decomposition reactor, such as an electrolytic reactor or a reactor that includes an active metal, such as an alloy of sodium and potassium. Particular implementations include a housing that at least partially encloses the condensation unit. The housing may include an aperture, which may be covered by a screen, mesh, or filter. The housing may also include a fan. The fan is used, in some examples, to draw air through the aperture. The monitoring device is, in some implementations, configured for remote operation, such as including a power supply or transmitter.

Abstract: The invention provides materials and methods for making anisotropic solids which may be in the form of films, layers, shaped elements, and other shaped articles. The methods provide anisotropic solids without the need for rolling, rubbing, or stretching to impart orientational alignment of the molecules of the solid. The methods employ organic or organometallic compounds which are soluble orienting molecules. The solvent or solvent system must be sufficiently volatile to be removed without disruption of the molecular orientation. The soluble orienting molecules include those containing one or more hydrophilic and/or ionic groups and the solvent or solvent system can be a polar organic solvent or solvent system or an aqueous solvent or solvent system. The invention also provides novel compounds having quaterrylene, perylene and naphthalene ring systems carrying one or more hydrophilic and/or ionic groups.

Abstract: Embodiments of a method for selecting particles, such as based on their morphology, is disclosed. In a particular example, the particles are charged and acquire different amounts of charge, or have different charge distributions, based on their morphology. The particles are then sorted based on their flow properties. In a specific example, the particles are sorted using a differential mobility analyzer, which sorts particles, at least in part, based on their electrical mobility. Given a population of particles with similar electrical mobilities, the disclosed process can be used to sort particles based on the net charge carried by the particle, and thus, given the relationship between charge and morphology, separate the particles based on their morphology.

Abstract: The present disclosure provides methods and systems for purifying liquids. In a particular implementation, the system includes a forward-osmosis unit for diluting a water source for a downstream desalination unit. A pretreatment unit may be located hydraulically upstream of the desalination unit, such as upstream or downstream of the forward-osmosis unit. In certain embodiments, the system includes an extraction unit for extracting a relatively easily extractable osmotic agent from an osmotic draw solution. The system may include one or more forward-osmosis units downstream of the desalination unit for diluting a concentrated brine stream produced by the desalination unit. In particular embodiments, a downstream forward-osmosis unit uses the concentrated brine stream as an osmotic agent, such as to extract water from seawater or brackish water. Another downstream forward-osmosis unit may use impaired water as a feed stream.

Abstract: Embodiments for monitoring one or more utilities consumed within a monitored area including detecting an amount of a first utility consumed by a load associated with a device and an amount of a second utility consumed by a load associated with the device. The identity of the device is determined based on the amount of the first and second utility consumed. A utility monitoring method is disclosed that includes measuring an amount of a utility consumed by a first device at a first time and an amount of a utility consumed by a second device at a second time. The identity of the first device is determined based on the measured consumption of the first and second devices at the first and second time. In certain implementations, the electricity meter uses an effective variance analysis of the conductance waveform on an electrical circuit to identify specific appliances.

Abstract: Certain disclosed embodiments provide sensing devices of the type useable to obtain measurements from a plurality of positions of a substrate, such as in a well, body of water, soil, snow pack, or ice pack. In a particular implementation, the sensing device includes a housing having a length. A plurality of digital sensors are disposed at a plurality of positions along the length of the housing. A communication bus is in communication with each of the plurality of sensors. A data collection or transmission device is in communication with the communication bus. Further implementations provide sensing devices having a housing formed from a plurality of modular sections. Sensors are disposed in at least one of the modular sections. Also disclosed are networks formed from a plurality of the disclosed devices.

Abstract: Photoacoustic instruments and their methods of use are disclosed. Certain disclosed photoacoustic instruments include a resonator cavity, an acoustic detector, a laser, an optical power detector, and a scattering detector. Further disclosed photoacoustic instruments include a resonator cavity, an acoustic detector, an optical power detector, a plurality of laser beams, each laser beam having a different wavelength, and, optionally, a scattering detector.

Abstract: Methods and apparatus are disclosed for characterizing flow of magneto-rheological suspensions through microchannels. The apparatus includes a pump for pumping a the magneto-rheological suspension; a microchannel hydraulically coupled to the pump and configured to receive the magneto-rheological suspension from the pump; a manifold hydraulically coupled between an outlet of the microchannel and the pump; a static pressure tap configured to convey a static pressure of the manifold; a pressure sensor hydraulically coupled to the pressure tap and configured to receive the static pressure conveyed therefrom; and a magnet positioned to direct a magnetic field toward the microchannel and contents disposed therein.

Abstract: A disclosed chemical detection system for detecting a target material, such as an explosive material, can include a cantilevered probe, a probe heater coupled to the cantilevered probe, and a piezoelectric element disposed on the cantilevered probe. The piezoelectric element can be configured as a detector and/or an actuator. Detection can include, for example, detecting a movement of the cantilevered probe or a property of the cantilevered probe. The movement or a change in the property of the cantilevered probe can occur, for example, by adsorption of the target material, desorption of the target material, reaction of the target material and/or phase change of the target material. Examples of detectable movements and properties include temperature shifts, impedance shifts, and resonant frequency shifts of the cantilevered probe. The overall chemical detection system can be incorporated, for example, into a handheld explosive material detection system.

Abstract: Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals against Bacillus anthracis or other capsulated pathogens. The methods include administering a capsular polypeptide of a pathogen of interest and a CD40 agonist to a human or animal. The capsular polypeptide or the CD40 agonist is administered in such an amount or frequency that an immunoprotective response can be elicited in the human or animal against the pathogen of interest. In another aspect, the present invention provides methods of using passive immunization with anti-capsular polypeptide antibodies to prevent or treat infections caused by Bacillus anthracis or other pathogens. In yet another aspect, the present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum or other biological samples.

Abstract: The present disclosure provides methods and systems for purifying an impaired liquid. In a particular example, the disclosure provides methods and systems for purifying water containing a solute. A feed stream of solute containing water is introduced in a flow chamber. A permeate stream of water at least substantially free of the solute is placed in the flow chamber. A hydrophobic membrane is placed between the feed stream and the permeate stream. A vacuum is applied to the permeate stream. A vapor pressure differential causes water to vaporize from the feed stream, pass through the hydrophobic membrane, and condense in the permeate stream.

Abstract: An electrode-less discharge source of extreme ultraviolet (EUV) radiation (10) efficiently assembles a hot, dense, uniform, axially stable plasma column (5) with magnetic pressure and inductive current drive. It employs theta-pinch-type magnetic compression of plasma confined in a magnetic mirror. Plasma, confined in a magnetic mirror, is made to radiate by resonant magnetic compression. The device comprises a radiation-source gas input nozzle (1), an optional buffer-gas input flow (2), mirror-field coils (9a, 9b), theta-pinch coils (8a, 8b), a plasma and debris dump (11), and an evacuation port (7). The circular currents yield an axially stable plasma-magnetic-field geometry, and a reproducible, stable, highly symmetrical EUV source.

Abstract: Apparatus to facilitate reduction and fixation of a fracture by drawing together the fracture by applying tension to a reduction wire are disclosed. These apparatus include a bone plate for the fixation of a fractured bone having a plurality of fastener openings so that the bone plate may be secured by a plurality of fasteners across a reduced fracture to fixate a reduced fracture. The bone plate is configured with a channel that receives a reduction wire so that the reduction wire may extend between the bone plate and a reduction wire mount such as a bone screw.