Patents Represented by Attorney Vanet E. Hasak

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  • Peptide antibodies and their use in detecting oncogene products
    Patent number: 4762706
    Abstract: Antibodies exhibit specificity toward single amino acid differences between proteins. These antibodies may be produced by synthesizing a peptide of the appropriate amino acid sequence contained in the protein, immunizing a host with the peptide, and extracting sera from the host to obtain the antibodies. The antibodies and the desired protein are then immunoprecipitated under conditions of partial denaturation to expose the epitope of the protein. The antibodies may be used for diagnostic or therapeutic purposes.
    Type: Grant
    Filed: October 17, 1984
    Date of Patent: August 9, 1988
    Assignees: Cetus Corporation, Cold Spring Harbor Laboratories
    Inventors: Francis P. McCormick, Gail L. Wong, Robin Clark, Norman Arnheim, Danute E. Nitecki, James R. Feramisco