Patents Represented by Attorney Verenium Corporation

Find this attorney in the Justia Lawyer Directory

  • Nucleic acids encoding nitrilases
    Patent number: 8334125
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: December 18, 2012
    Assignee: Verenium Corporation
    Inventors: Grace DeSantis, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay Short, David Weiner, Mark Madden, Darcy Madden, legal representative, Mark Burk, Dan Robertson
  • Nitrilases, nucleic acids encoding them and methods for making and using them
    Patent number: 8318471
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: November 27, 2012
    Assignee: Verenium Corporation
    Inventors: Grace Desantis, Jay M. Short, Mark J. Burk, Kelvin Wong, Robert Farwell, Kelly Chatman
  • Chemoenzymatic methods for the synthesis of statins and statin intermediates
    Patent number: 8148324
    Abstract: The invention provides aldolases, nucleic acids encoding them and methods for making and using them, including chemoenzymatic processes for making ?,?-dihydroxyheptanoic acid side chains and compositions comprising these side chains, e.g., [R—(R*,R*)]-2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-(phenylamino)-carbonyl]-1H-pyrrole-1-heptanoic acid (atorvastatin, LIPITOR™), rosuvastatin (CRESTOR™), fluvastatin (LESCOL™), related compounds and their intermediates.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: April 3, 2012
    Assignee: Verenium Corporation
    Inventors: William Greenberg, Mark J. Burk, Alexander Varvak, Kelvin Wong
  • Laccases, nucleic acids encoding them and methods for making and using them
    Patent number: 8097442
    Abstract: The invention provides laccases, polynucleotides encoding these enzymes, the methods of making and using these polynucleotides and polypeptides.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: January 17, 2012
    Assignee: Verenium Corporation
    Inventors: Tim S. Hitchman, Dan E. Robertson, Masao Hiraiwa, Yoko Phillips, Kevin A. Gray
  • Nitrilases, nucleic acids encoding them and methods for making and using them
    Patent number: 8088613
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: January 3, 2012
    Assignee: Verenium Corporation
    Inventors: Mark Burk, Kelly Chatman, Grace Desantis, Bob Farwell, Jay M. Short, Kelvin Wong
  • Amylases, nucleic acids encoding them and methods for making and using them
    Patent number: 8071350
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used as amylases to catalyze the hydrolysis of starch into sugars.
    Type: Grant
    Filed: April 7, 2010
    Date of Patent: December 6, 2011
    Assignee: Verenium Corporation
    Inventors: Kevin A. Gray, Nahla Aboushadi, James B. Garrett
  • Pectate lyases, nucleic acids encoding them and methods for making and using them
    Patent number: 8067222
    Abstract: The invention is directed to polypeptides having pectate lyase (pectinase) activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used as pectate lyases to catalyze the beta-elimination or hydrolysis of pectin and/or polygalacturonic acid, such as 1,4-linked alpha-D-galacturonic acid. The invention provides methods of treating fibers, fabrics or any pectate- or polygalacturonic acid-comprising material using one or more pectate lyases of the invention.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: November 29, 2011
    Assignee: Verenium Corporation
    Inventors: Janne Kerovuo, Arne Solbak, Kevin Gray, Ryan McCann, Shalaka Purohit, Joel Gerendash, Giselle Janssen, Samun Dahod
  • Nitrilases and methods for making and using them
    Patent number: 7993901
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: August 9, 2011
    Assignee: Verenium Corporation
    Inventors: Grace Desantis, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay Short, David Weiner, Mark Madden, Marcy Madden, legal representative, Mark Burk, Dan Robertson
  • Phospholipases, nucleic acids encoding them and methods for making and using them
    Patent number: 7943360
    Abstract: The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
    Type: Grant
    Filed: January 22, 2007
    Date of Patent: May 17, 2011
    Assignee: Verenium Corporation
    Inventors: Svetlana Gramatikova, Geoff Hazlewood, David Lam, Nelson R. Barton, Blake G. Sturgis, Dan E. Robertson, Jincai Li, Joel A. Kreps, Roderick James Fielding, Robert C. Brown, Amit Vasavada, Xuqiu Tan, Adrian Badillo, Wilhelmus P. Van Hoek, Giselle Janssen, Charles Isaac, Mark J. Burk
  • Nitrilases, nucleic acids encoding them and methods for making and using them
    Patent number: 7811804
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: October 12, 2010
    Assignee: Verenium Corporation
    Inventors: Grace DeSantis, Jay Short, Mark Burk, Kelvin Wong, Kelly Chatman, Bob Farwell
  • Amylases, nucleic acids encoding them and methods for making and using them
    Patent number: 7741092
    Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used as amylases to catalyze the hydrolysis of starch into sugars.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: June 22, 2010
    Assignee: Verenium Corporation
    Inventors: Kevin A. Gray, Nahla Aboushadi, James B. Garrett
  • Methods for making simvastatin and intermediates
    Patent number: 7700329
    Abstract: The invention provides synthetic chemical and chemoenzymatic methods of producing simvastatin and various intermediates. In one aspect, enzymes such as hydrolases, e.g., esterases, are used in the methods of the invention.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: April 20, 2010
    Inventors: Brian Morgan, Mark Burk, Michael Levin, Zuolin Zhu, Jennifer Chaplin, Karen Kustedjo, Zilin Huang, William Greenberg
  • Enzymes having dehalogenase activity and methods of use thereof
    Patent number: 7671189
    Abstract: The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: March 2, 2010
    Assignee: Verenium Corporation
    Inventors: Jay M. Short, Toby Richardson, Dan E. Robertson, Kevin A. Gray
  • Methods for generating cellulases
    Patent number: 7422876
    Abstract: The invention relates to carboxymethyl cellulases and to polynucleotides encoding the carboxymethyl cellulases. In addition methods of designing new carboxymethyl cellulases and method of use thereof are also provided. The carboxymethyl cellulases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: January 11, 2005
    Date of Patent: September 9, 2008
    Assignee: Verenium Corporation
    Inventors: Jay M. Short, Eric J. Mathur, David E. Lam
  • Glycosidase enzymes
    Patent number: 7294498
    Abstract: A thermostable glycosidase enzymes derived from various Thermococcus, Staphylothermus and Pyrococcus organisms is disclosed. The enzymes are produced from native or recombinant host cells and can be utilized in the food processing industry, pharmaceutical industry and in the textile industry, detergent industry and in the baking industry.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: November 13, 2007
    Assignee: Verenium Corporation
    Inventors: Edward J. Bylina, Ronald V. Swanson, Eric J. Mathur, David E. Lam
  • Enzymes having glycosidase activity and methods of use thereof
    Patent number: 7279316
    Abstract: The invention relates to glycosidases and to polynucleotides encoding the glycosidases. In addition methods of designing new glycosidases and method of use thereof are also provided. The glycosidases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: October 9, 2007
    Assignee: Verenium Corporation
    Inventors: Jay M. Short, Edward Bylina, Ronald V. Swanson, Eric J. Mathur, David E. Lam