Patents Represented by Attorney, Agent or Law Firm Victoria M. Malia
  • Patent number: 6226084
    Abstract: The invention relates to a method of calibrating an optical system, the system comprising a flash lamp as a light source (4), a lens system (6), a monochromator comprising a grating (10), a motor (20) for displacing the grating so as to enable scanning essentially monochromatic light over a detection system. The light source provides at least two high intensity peaks at distinct wavelengths. The method comprises scanning a first wavelength region comprising at least one of said at least two high intensity peaks, and measuring the intensities at a selected number of points during the scan. A first of said at least two peaks is coarsely located. A wavelength region around each of said at least two peaks is scanned, measuring the intensities at closer intervals than previously. At least two peaks are located by autocorrelation. The location of said peaks is determined in terms of a distance from a reference point, said distance corresponding to said displacement of the grating.
    Type: Grant
    Filed: December 29, 1998
    Date of Patent: May 1, 2001
    Assignee: Amersham Pharmacia Biotech AB
    Inventor: Stig Tormod
  • Patent number: 6173603
    Abstract: A cassette is used with a chemical immobilization and treatment system. The system with the cassette performs various complex chemistries with minimal human intervention, near-zero dead volume, and flow-through protocols pursuant to a predetermined instruction set encoded on a multiple-address chemical treatment cassette assembly. The cassette assembly comprises a plurality of analyte sample columns (“mini-columns”), having a high-pressure interface capability to permit direct insertion of the mini-column into a high-pressure solvent line for use as a support column for HPLC analysis. A sample loader loads analyte samples either singly or simultaneously into the multiple, addressable mini-columns without the need to load the sample funnel/column assembly into a separate reaction chamber.
    Type: Grant
    Filed: September 3, 1998
    Date of Patent: January 16, 2001
    Assignee: Amersham Pharmacia Biotech AB
    Inventor: Marcus J. Horn
  • Patent number: 6168760
    Abstract: This invention is directed to a cassette chemical chemical treatment station. The system with the cassette performs various complex chemistries with minimal human intervention, near-zero dead volume, and flow-through protocols pursuant to a predetermined instruction set encoded on a multiple-address chemical treatment cassette assembly. The cassette assembly having a high pressure interface capability to permit direct insertion of the mini-column into a high-pressre solvent line for use as a support column for HPLC analysis. A sample loader loads analyte samples either singly or simultaneously into the multiple, addressable mini-columns without the need to load the sample funnel/column assembly into a separate reaction chamber.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: January 2, 2001
    Assignee: Amersham Pharmacia Biotech AB
    Inventor: Marcus J. Horn
  • Patent number: 6113766
    Abstract: The present invention involves a gel strip carrier module for a gel strip that reduces the handling of the gel strip and the hands-on-time during preparation of the gel strip for isoelectric focusing. The gel carrier module includes a gel strip chamber that serves as both a rehydration and focusing chamber, and allows the sample to be applied either throughout the entire gel or in a defined zone. The gel carrier module includes a pair of electrodes near opposite ends of the chamber that the gel strip rests on, gel side facing down. The gel carrier module includes a cover with hold-down blocks or pressure blocks to assure reliable, light contact between the gel and the electrodes during focusing. A rehydration buffer is added into the chamber, and the gel strip is gently placed in the chamber, gel side down, for rehydration.
    Type: Grant
    Filed: June 9, 1998
    Date of Patent: September 5, 2000
    Assignee: Hoefer Pharmacia Biotech, Inc.
    Inventors: Urs Steiner, Mohammed Rezaul Islam, Eric R. Hungerman
  • Patent number: 6110340
    Abstract: The present invention involves a gel casting and electrophoresis device that simplifies the gel cassette casting and electrophoresis process by providing an integral frame assembly that includes a bottom sealing means movable to a first position where the sealing means seals the bottom of the gel cassette for gel casting purposes and a second position which exposes the bottom of the gel cassette for electrophoresis purposes.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: August 29, 2000
    Assignee: Hoefer Pharmacia Biotech, Inc.
    Inventors: Timothy O. Lau, Urs Steiner, Eric Coates, Thomas S. Acampora
  • Patent number: 6013704
    Abstract: There are described compounds of formula A whereinr.sub.1 and r.sub.2 are each independently of the other 0 or 1;Y.sub.1 to Y.sub.9 are each independently of the others --H, --OH, C.sub.1 -C.sub.20 alkyl, C.sub.4 -C.sub.20 cycloalkyl, C.sub.2 -C.sub.20 -alkenyl, C.sub.1 -C.sub.20 alkoxy, C.sub.4 -C.sub.12 cycloalkoxy, C.sub.2 -C.sub.20 alkenyloxy, C.sub.7 -C.sub.20 aralkyl, halogen, --C.tbd.N, C.sub.1 -C.sub.5 haloalkyl, --SO.sub.2 R', --SO.sub.3 H, --SO.sub.3 M, wherein M is an alkali metal, --COOR', --CONHR', --CONR'R", --OCOOR', --OCOR', --OCONHR', (meth)acrylamino, (meth)-acryloxy, C.sub.6 -C.sub.12 aryl; C.sub.6 -C.sub.12 aryl substituted by C.sub.1 -C.sub.12 alkyl, C.sub.1 -C.sub.12 alkoxy, CN and/or by halogen; C.sub.3 -C.sub.12 heteroaryl; C.sub.3 -C.sub.12 heteroaryl substituted by C.sub.1 -C.sub.12 alkyl, C.sub.1 -C.sub.12 alkoxy, CN and/or by halogen; or Q of formula I, and at least one substituent Y.sub.1 to Y.sub.9 must be Q ##STR1## wherein q is 0 or 1,R is a cyclic radical andR.sub.
    Type: Grant
    Filed: September 10, 1997
    Date of Patent: January 11, 2000
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Pascal Hayoz, Andreas Valet, Vien Van Toan
  • Patent number: 5973085
    Abstract: Compounds of the formula I(A).sub.n --B (I)in which A is the radical of a strained cycloolefin, B is a direct bond or an n-valent bridging group and n is an integer from 2 to 8, with the exception of 1,2-bisnorbornenyl-ethane and norbornenecarboxylic acid norbornenemethyl ester. The compounds of the formula I can be polymerized with one-component catalysts (ring-opening metathesis polymerization).
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: October 26, 1999
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Andreas Muhlebach, Andreas Hafner, Paul Adriaan Van Der Schaaf
  • Patent number: 5892051
    Abstract: Compounds of formula I,R--S--CH.sub.2 CH(OH)CH.sub.2 --S--R.sup.4 (I),where R is tert-alkyl of 4 to 20 carbon atoms and 4 is benzothiazolyl, --(CH.sub.2).sub.m --S--CH.sub.2 CH(OH)CH.sub.2 --S--(C.sub.1 -C.sub.16 alkyl), m is 0, or --(CH.sub.2).sub.s --R.sup.7 where s is 1 to 4 and R.sup.7 is benzothiazolyl are effective additives for lubricants, hydraulic fluids or other lubricant systems. Some novel compounds of formula I are claimed.
    Type: Grant
    Filed: December 16, 1996
    Date of Patent: April 6, 1999
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Hermann O. Wirth, Hans-Helmut Friedrich
  • Patent number: 5859102
    Abstract: Plastic mixtures, in particular recycled plastic mixtures, comprising predominantly polyolefins and 0.05-20% by weight of PVDC can be stabilized against thermo-oxidative degradation by addition of a combination of an organic phosphite or phosphonite and a metal salt of a fatty acid.
    Type: Grant
    Filed: June 20, 1996
    Date of Patent: January 12, 1999
    Assignee: Ciba Speciality Chemicals Corporation
    Inventors: Rudolf Pfaendner, Heinz Herbst, Kurt Hoffmann
  • Patent number: 5854299
    Abstract: Process for the polymerization of cyclic olefins by photochemical ring-opening metathesis polymerization by irradiation, using catalytic amounts of a heat-stable ruthenium or osmium catalyst which has at least one photolabile ligand, the other coordination sites being occupied by non-photolabile ligands.
    Type: Grant
    Filed: March 8, 1996
    Date of Patent: December 29, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Andreas Muhlebach, Paul Bernhard, Andreas Hafner, Thomas Karlen, Martin Andreas Ludi
  • Patent number: 5814691
    Abstract: The invention relates to a PVC composition comprising a stabilizer combination of (b) polyDHP of the formula I ##STR1## where the radicals T, L, R, R', R" are as defined in claim 1, (c) a substance from the group consisting ofcrystalline hydrotalcites,crystalline or amorphous zeolites,crystalline or amorphous dawsonites, magadiites or kenyaites, disaccharide alcohols andsterically hindered amines containing the structural unit ##STR2## in which R.degree. is hydrogen or methyl, and (d) at least one zinc, aluminium or lanthanoid compound.
    Type: Grant
    Filed: December 4, 1995
    Date of Patent: September 29, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Karl Josef Kuhn, Wolfgang Wehner
  • Patent number: 5807966
    Abstract: An increase in the molecular weight of virgin polycondensates and polycondensate recyclates can be achieved by heating to above the melting point or glass transition temperature and by the addition of diphosphonite.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: September 15, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Rudolf Pfaendner, Heinz Herbst, Kurt Hoffmann
  • Patent number: 5804623
    Abstract: Recycled plastics, predominandy thermoplastics, from domestic, commercial and industrial waste can be stabilized against thermooxidative degradation by adding a combination of a sterically hindered phenol with an organic phosphite or phosphonite and a metal salt of a fatty acid.
    Type: Grant
    Filed: November 25, 1996
    Date of Patent: September 8, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Kurt Hoffmann, Heinz Herbst, Rudolf Pfaendner, Hans-Jurgen Sander, Franciszek Sitek
  • Patent number: 5795985
    Abstract: A novel process for the preparation of compounds of formula I ##STR1## by aminolysis of a p-halophenyl alkyl ketone of formula II ##STR2## with a cyclic amine of formula III ##STR3## in water at a temperature of at least 130.degree. C., in which formulae X is a halogen atom and R.sub.1, R.sub.2 and R.sub.3 are as claimed in claim 1, as well as the novel compounds of formula I and their use for the preparation of photoinitiators for the photopolymerisation of ethylenically unsaturated compounds.
    Type: Grant
    Filed: April 21, 1997
    Date of Patent: August 18, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Rinaldo Husler, Rudolf Schwabe, Reto Luisoli
  • Patent number: 5789470
    Abstract: The invention relates to stabilized recycled plastics, which can be obtained from domestic, commercial and industrial waste or valuable material collections, comprising a macrocyclic compounds containing a radical of formula (I) or (II), in the macrocycle or in a side group of the macrocycle, where the macrocycle comprises at least 8 atoms and in which the substituents R, independently of one another, are methyl, ethyl or propyl, or two radicals R on the same carbon atom are, together, a pentamethylene radical, and a is the number 0, 1 or 2. The invention also relates to a process for the stabilization of recycled plastics and to the use of the above macrocyclic compounds as stabilizer.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: August 4, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Heinz Herbst, Kurt Hoffmann, Franca Masina, Rudolf Pfaendner, Franciszek Sitek
  • Patent number: 5777113
    Abstract: The invention relates to novel compounds of formula I ##STR1## wherein the general symbols are as defined in claim 1, as stabilizers for organic materials against oxidative, thermal or light-induced degradation.
    Type: Grant
    Filed: October 10, 1995
    Date of Patent: July 7, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventor: Rita Pitteloud
  • Patent number: 5777008
    Abstract: Novel oligomeric compounds of formula I ##STR1## wherein the general symbols are as defined in claim 1, are disclosed as stabilisers for protecting organic material against oxidative, thermal or light-induced degradation.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: July 7, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventor: Rita Pitteloud
  • Patent number: 5773631
    Abstract: The invention described novel compounds of formula ##STR1## wherein the general symbols are as defined in claim 1, as stabilisers for protecting organic materials, in particular polymers and lubricants, against thermal, oxidative or light-induced degradation.
    Type: Grant
    Filed: February 26, 1996
    Date of Patent: June 30, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Peter Nesvadba, Samuel Evans, Christoph Krohnke, Jurg Zingg
  • Patent number: 5772921
    Abstract: The present invention relates to synergistic mixtures of at least one 2,4-dimethyl-6-s-alkyl phenol and at least one selected sterically hindered phenol according to formula II ##STR1## The variable "n" is 1, 2 or 4. X.sub.1 is tert-butyl. X.sub.2 is C.sub.1 -C.sub.4 alkyl. X.sub.3, when n is 1, is C.sub.1 -C.sub.20 alkyl, a triazinylamino group, or a --A.sub.1 --COO--A.sub.2 or --A.sub.1 --CONH--A.sub.2 group. X.sub.3, when n is 2, is a --E.sub.1 --COO--E.sub.2 --OOC--E.sub.3 -- or --E.sub.1 --CONH--E.sub.2 --NHCO--E.sub.3 -- group. X.sub.3, when n is 4, is ?--G.sub.1 --COO!.sub.4 --G.sub.2. The instant synergistic mixtures can be used to stabilize selected organic polymers against thermal, oxidative and/or actinic degradation.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: June 30, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Bernard Gilg, Kurt Stinsky
  • Patent number: 5770643
    Abstract: The invention relates to compositions comprisinga) a chlorine-containing polymer andb) at least one compound containing at least one radical of the formula I ##STR1## in which A is the additional groups or atoms necessary to form an unsubstituted or substituted six-membered heterocyclic ring containing two nitrogen ring atoms.
    Type: Grant
    Filed: March 20, 1996
    Date of Patent: June 23, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Wehner, Hans-Helmut Friedrich, Rolf Drewes