Abstract: A variety of low molecular weight, guanidino-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases. The compounds have the structure of Formulas (IA), (IB), or (IC): where the values of the variable are defined herein.
Type:
Grant
Filed:
May 23, 2003
Date of Patent:
December 28, 2010
Assignee:
Novartis Vaccines and Diagnostics, Inc.
Inventors:
Rustum S. Boyce, Natalia Aurrecoechea, Daniel Chu, Aaron Smith, Bryan Chang