Patents Represented by Attorney Walter E. Butting
  • Patent number: 4082774
    Abstract: Methylenation of catechol by reaction with a methylene dihalide under alkaline conditions is improved by adding the pre-formed catechol dianion in a heated protic alkaline medium to a solution of methylene dihalide in dimethyl sulfoxide.
    Type: Grant
    Filed: July 11, 1974
    Date of Patent: April 4, 1978
    Assignee: Eli Lilly and Company
    Inventor: John A. Kirby
  • Patent number: 4001226
    Abstract: 7-Acylamino and 7-amino-3-(substituted)carbonylamino-3(or 2)-cephem-4-carboxylic acids and esters thereof, which are useful as antibiotics or as intermediates in preparing antibiotic substances respectively, are prepared from 7-acylamino-3-azidocarbonyl-2(or 3)-cephem-4-carboxylic acid esters via the corresponding thermally derived 3-isocyanatocephem derivatives.
    Type: Grant
    Filed: December 4, 1974
    Date of Patent: January 4, 1977
    Assignee: Eli Lilly and Company
    Inventor: Douglas O. Spry