Abstract: Human urokinase is produced using recombinant DNA techniques. The invention disclosed thus enables the production of urokinase free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.
Type:
Grant
Filed:
July 19, 1988
Date of Patent:
May 12, 1992
Assignee:
Genentech, Inc.
Inventors:
Herbert L. Heyneker, William E. Holmes, Gordon A. Vehar