Patents Represented by Law Firm Weiser And Associates, P.C.
  • Method for synthesizing single-stranded stem-loop DNAs, the products and uses therefor
    Patent number: 5643762
    Abstract: The invention provides a method for synthesizing new and useful single-stranded DNAs which have a stem-loop configuration (ss-slDNA). The method is an in vivo or in vitro synthesis. Replicating vehicles are provided which produce these ss-slDNAs. The slDNAs can be used for introducing random mutations in a selected gene, and they lend themselves for replication by a variant of the PCR method.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: July 1, 1997
    Assignee: University of Medicine And Denistry Of New Jersey
    Inventors: Atsushi Ohshima, Sumiko Inouye, Masayori Inouye