Patents Represented by Law Firm Weiser & Associates
  • Patent number: 6074818
    Abstract: Improvements to nucleic acid fingerprinting are disclosed. The method generates profiles of increased fidelity characteristic of the nucleic acids analyzed. Novel primers and other means are taught. Useful products are disclosed.
    Type: Grant
    Filed: October 20, 1993
    Date of Patent: June 13, 2000
    Assignee: The University of Tennessee Research Corporation
    Inventors: Gustavo Caetano-Anolles, Brant J. Bassam, Peter M. Gresshoff
  • Patent number: 6043028
    Abstract: A method of synthesis of new and useful single-stranded DNAs which have a stem-loop configuration (ss-slDNA). The method is an in vivo or an in vitro synthesis. Replicating vehicles which produce these ss-slDNAs. The ss-slDNAs are described. Uses for these slDNAs are disclosed. They can be used for introducing random mutations, they lend themselves for replication by a variant of the PCR method. They can also be used for regulating gene function. Other uses are disclosed.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: March 28, 2000
    Assignee: University of Medicine and Dentistry of New Jersey
    Inventors: Atsushi Ohshima, Sumiko Inouye, Masayori Inouye
  • Patent number: 6036995
    Abstract: A method for removing surface layers of a metal coating is disclosed. The method comprises applying an aluminum containing slurry to the surface of the metal coating, melting and diffusing the aluminum to form an aluminide layer within the surface of the metal coating, and removing the aluminide layer.
    Type: Grant
    Filed: January 31, 1997
    Date of Patent: March 14, 2000
    Assignee: Sermatech International, Inc.
    Inventors: Thomas A. Kircher, Bruce G. McMordie, Mark F. Mosser
  • Patent number: 6025093
    Abstract: The invention relates to a lithium ion cell, comprising a positive electrode which contains a chalkogen compound, containing lithium, of a transition metal, a non-aqueous electrolyte and a negative electrode which is separator-isolated and contains carbon, which is characterized in that the cell contains lithium metal or a lithium alloy in a form physically separated from the electrodes, the lithium metal or the lithium alloy having a connection for the main lead of an electrode and, via the electrolyte, an ionic connection for the electrodes.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: February 15, 2000
    Assignee: Varta Batterie Aktiengesellschaft
    Inventor: Rudolf Herr
  • Patent number: 6017737
    Abstract: A multicopy single-stranded DNA (msDNA) synthesizing system in E. coli is disclosed. The use of the msDNA system to synthesize cDNA in vivo is disclosed. Construction of synthetic msDNA is also disclosed. Also processes for gene amplification and for producing a stable RNA are disclosed.
    Type: Grant
    Filed: April 11, 1995
    Date of Patent: January 25, 2000
    Assignee: The University of Medicine and Denistry of New Jersey
    Inventors: Masayori Inouye, Sumiko Inouye
  • Patent number: 6015292
    Abstract: Dental reamers are manufactured from a cylindrical metallic blank (e.g., made of a nickel-titanium alloy) that is moved at a feed speed V.sub.A past a rotary grinding wheel whose disk, of variable diameter, determines a linear speed V.sub.L at which material is removed. The feed speed V.sub.A is greater than 91440 cm/min, while the linear speed V.sub.L is less than 7.62 cm/min.
    Type: Grant
    Filed: January 22, 1998
    Date of Patent: January 18, 2000
    Assignee: Micro-Mega International Manufactures
    Inventors: Hubert Euvrard, Denis Chevillot
  • Patent number: 6013470
    Abstract: The present invention relates to the cloning of a member of a new potassium channel named TWIK-1. More specifically, it relates to an isolated and purified nucleic acid molecule coding for a protein constituting a potassium channel exhibiting the properties and structure of the TWIK-1 type channel, as well as the protein coded by this nucleic acid molecule.The invention also relates to the use of this nucleic acid molecule to transform cells, and the use of these cells expressing the potassium channels exhibiting the properties and structure of the TWIK-1 type channel for the screening of drugs.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: January 11, 2000
    Assignee: Centre National de la Recherche Scientifique-CNRS
    Inventors: Florian Lesage, Eric Guillemare, Michel Fink, Fabrice Duprat, Michel Lazdunski, Georges Romey, Jacques Barhanin
  • Patent number: 6007944
    Abstract: The invention relates to a rechargeable lithium-ion cell, a method for its manufacture, and its application. The cell is distinguished by the fact that it has a metallic housing (21) which is electrically insulated internally by two half shells (15), which cover electrode plates (8) and main output tabs (7) and are composed of a non-conductive material, where the metallic housing is electrically insulated externally by means of an insulation coating. The cell also has a bursting membrane (4) which, in its normal position, is located above the electrolyte level of the cell (1). In addition, the cell has a twisting protection (6) which extends over the entire surface of the cover (2) and provides centering and assembly functions for the electrode package, which comprises the electrode plates (8).
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: December 28, 1999
    Assignee: Varta Batterie Aktiengesellschaft
    Inventors: Dieter Bechtold, Dietrich Bartke, Peter Kramer, Reiner Kretzschmar, Jurgen Vollbert
  • Patent number: 5984483
    Abstract: A dual state mirror assembly for use with motor vehicles includes a housing having an open front for receiving an outer substrate to form an enclosure. The outer substrate has a surface coated with a thin metal film to act as a beam splitter. An inner substrate having a reflective front surface is mounted within the enclosure so that in a first position, the inner substrate is in direct contact with the outer substrate, to produce a single bright reflected image, and so that in a second position, the inner substrate is placed at an angle with respect to the outer substrate, to provide a dimmed image and to minimize glare.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: November 16, 1999
    Inventors: Niel Mazurek, Theodore J. Zammit
  • Patent number: 5985454
    Abstract: Multilayered coatings comprising a sacrificial primer layer, a non-sacrificial second layer, and a polymer topcoat are disclosed.
    Type: Grant
    Filed: October 14, 1997
    Date of Patent: November 16, 1999
    Assignee: Sermatech International Incorporated
    Inventors: Bruce G. McMordie, Mark F. Mosser
  • Patent number: 5981280
    Abstract: A method of inhibiting the translation of bacterial mRNA is disclosed, which method comprises overexpressing in a bacterium an mRNA which contains a sequence which is complementary to the anti-downstream box region of the 16S rRNA. RNA and DNA constructs for the overexpression of the mRNA of the invention are disclosed.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: November 9, 1999
    Assignee: The University of Medicine and Denistry of New Jersey
    Inventors: Li Fang, Weining Jiang, Masanori Mitta, Masayori Inouye
  • Patent number: 5974978
    Abstract: A lightweight, remote-controlled, self-propelled equipment support and transport system is stabilized against unwanted angular deviation in each of three perpendicular axes and adapted for motion at high speed along a simple tubular monorail. The system can be quickly and efficiently ground-mounted on stands, suspended horizontally from brackets or from a variety of overhead supports, or vertically mounted alongside a mast or wall. The system includes an elongated drive car running on and partly surrounding a rail, and an equipment support associated with the drive car and configured so that the supported equipment is transversely and longitudinally spaced and balanced about a point just below the center of the rail. The equipment support is mounted in angular isolation relative to the drive car by a system of damped pivots about pitch and yaw axes.
    Type: Grant
    Filed: May 14, 1998
    Date of Patent: November 2, 1999
    Inventors: Gerrett W. Brown, David Keller
  • Patent number: 5975899
    Abstract: The present invention relates to a dental reamer (2) which tapers right down to its tip (1), of the type including helical slits which, on their sides, have cutting lips for boring out dental canals, in which the characteristics of the cutting conditions are defined by, on the one hand, a cutting angle .alpha. determined by the tangent to the cutting edge at the cutting point and the perpendicular to the surface to be cut at this point and, on the other hand, a clearance angle .beta. determined by the plane of the cutting surface and the tangent to the inactive face of the cutting edge, characterized in that the value of the cutting angle .alpha. is greater than or equal to zero and that of the clearance angle .beta. is greater than zero.
    Type: Grant
    Filed: November 18, 1997
    Date of Patent: November 2, 1999
    Assignee: Micro-Mega International Manufactures
    Inventors: Jean-Marie Badoz, Paul Calas, Hubert Euvrard, Jean-Marie Vulcain
  • Patent number: 5976892
    Abstract: A method for counting cells and microorganisms in a fluid medium, particularly in food and biological fluids, by labelling with a colored or fluorescent label which selectively labels the microorganisms and cells to be detected, and counting the labelled microorganisms and cells, wherein said colored or fluorescent label is a stoichiometric label, particularly a DNA or RNA label, the microorganisms and cells are concentrated at the same time as or prior to counting by means of a fluid medium concentration step, and counting is achieved by measuring the overall brightness of the concentrated medium and comparing it with a calibration curve.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: November 2, 1999
    Assignee: Biocom, S.A.
    Inventor: Jean-Claude Bisconte
  • Patent number: 5974303
    Abstract: A battery housing for an electrical device, such as a portable telephone, has a locking mechanism that locks the battery housing in place onto the housing of the portable device. The locking mechanism has a locking finger that is inserted into an opening in the device housing. The locking finger is spring mounted on the housing bottom of the battery housing and collaborates with at least one sliding surface which preferably has the shape of an inclined plane over which the locking finger can be forced out of the locked position by means of a movable key.
    Type: Grant
    Filed: April 18, 1997
    Date of Patent: October 26, 1999
    Assignee: Varta Batterie Aktiengesellschaft
    Inventor: Manfred Krause
  • Patent number: 5971044
    Abstract: A wood-splitting tool includes at least one system with n parallel elemental wedges (3a, 3b, 3c, . . . 3n) which in succession are given a movement for penetrating the wood. The system for actuating the wedges can be a hydraulic, chain-type, connecting rod-type, or percussive-type system attached to a motive power unit.
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: October 26, 1999
    Inventor: Herve Valentin
  • Patent number: 5968734
    Abstract: Translocations of chromosome 22 are associated with various cancers. Hybrid DNA sequences, having a portion of the Ews gene of chromosome 22 and a portion of either the Hum-Fli-1 gene of chromosome 11, the Erg gene of chromosome 21, or the Atf-1 gene of chromosome 12, are disclosed. Proteins encoded by these hybrid DNAs are disclosed. Diagnosis of specific cancers based on detection of the translocations is disclosed.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: October 19, 1999
    Assignee: (CNRS Centre National de la Recherche Scientifique
    Inventors: Alain Aurias, Olivier Delattre, Chantal Desmaze, Thomas Melot, Martine Peter, Beatrice Ploougastel, Gilles Thomas, Jessica Zucman
  • Patent number: 5968231
    Abstract: A device and a method for purifying and decontaminating air uses an exchanger of the cyclone type and furthermore employs a combination of the action of cyclonic centrifugation and the action of at least one path enhancing field. A tranquilizing chamber, which is separated from the cyclone exchanger by a vent, maintains a volume of liquid into which particles and droplets are received from the peripheral wall. To this end, particulates are partially electrified before entering the enhancing field.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: October 19, 1999
    Assignee: Grignotage, (SARL)
    Inventors: Michel Parmentier, Jean-Charles Weber
  • Patent number: 5955174
    Abstract: A web or film is electrostatically charged by sequentially subjecting the web or film to a series of electric fields such that adjacent electric fields have substantially opposite polarities. Both a method and apparatus are disclosed for charging the web or film.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: September 21, 1999
    Assignee: The University of Tennessee Research Corporation
    Inventors: Larry C. Wadsworth, Oldrich Jirsak, Peter Ping-Yi Tsai
  • Patent number: 5944523
    Abstract: A motor and handpiece assembly for driving a dental tool has a contra-angle and a motor. The contra-angle has a handle, a neck connected to the handle, and a head connected to the neck and adapted to hold the dental tool. The motor is adapted to drive the dental tool in different types of movement (e.g., continuous movement and alternating or vibratory movement). The invention provides a dental handpiece that can be used for different types of treatments using different types of dental tools that require different types of movement and different speeds.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: August 31, 1999
    Assignee: Micro-Mega International Manufactures
    Inventor: Jean-Marie Badoz