Abstract: A system of satellite communications provides high throughput data transmission rates for mobile terrestrial terminals. The system may allow point to point communication between two terrestrial terminals. Further, the system may allow point to multipoint communication from an initiating terrestrial terminal to a plurality of target terrestrial terminals. Still further, the system may allow multipoint to multipoint communication from a plurality of initiating terrestrial terminals to a plurality of target terrestrial terminals. The satellites in the system may utilizes on-board functionality such as routing, network management and other data handling functionality. Further, the satellites in the system may communicate amongst each other and route signals through in-box and inter-box communication.

Abstract: The present invention provides compounds for targeting endothelial cells, tumor cells or other cells that express the NP-1 receptor, compositions containing the same and methods for their use. Additionally, the present invention includes diagnostic, therapeutic and radiotherapeutic compositions useful for visualization, therapy or radiotherapy.

Abstract: A small antenna system for communications on-the-move (“COTM”) with a geostationary or geosynchronous satellite to and from a land mobile, maritime or airborne vehicle is disclosed. The antenna system provides a robust and simple means of establishing communications with a satellite or remote computer device. Further embodiments of systems and methods of the various aspects of the present invention mitigate RF losses customary in existing horn antennas. Embodiments also facilitate COTM by utilizing novel antenna configurations that tightly integrate RF electronics while dissipating generated heat via an antenna compartment that may be designed to function as or be used in conjunction with a heat sink.

Abstract: A method of making a lead frame and a partially patterned lead frame package with near-chip scale packaging lead-count, wherein the method lends itself to better automation of the manufacturing line and improved quality and reliability of the packages produced therefrom. A major portion of the manufacturing process steps is performed with a partially patterned strip of metal formed into a web-like lead frame on one side so that the web-like lead frame is also rigid mechanically and robust thermally to perform without distortion or deformation during the chip-attach and wire bond processes, both at the chip level and the package level. The bottom side of the metal lead frame is patterned to isolate the chip-pad and the wire bond contacts only after the front side, including the chip and wires, is hermetically sealed with an encapsulant. The resultant package being electrically isolated enables strip testing and reliable singulation.

Abstract: A system and method for authentication including verifying a password is disclosed. In one embodiment, the authentication system includes a first storage unit to store an authentication sequence, a read-only memory unit to store an authentication algorithm, and a second storage unit. A microcontroller is coupled to the first storage unit, the read-only memory unit, and is configured to be coupled to and uncoupled from a host. The microcontroller is configured to execute the authentication algorithm to verify a password with the authentication sequence, and to send an access request to a web server via the host if the authentication algorithm has verified the password with the authentication sequence.

Abstract: A method for fusing spinal bone is provided. The method comprises placing a sac between two or more adjacent sections of the spine to be fused, and filling the sac with bone tissue. The surfaces of the sac abutting the sections of the spine comprise porous material for allowing bone to grow between the spine and the sac. Surfaces of the sac not abutting the sections of the spine are nonporous to bodily fluids and thereby prevent premature deterioration of the bone tissue inside the sac. A sac for fusing spinal bone and a kit comprising the sac are also provided.

Abstract: An intraluminal endoprosthesis having a conically shaped first end and a tubular shaped balloon-expandable stent for a main body is disclosed. The conically shaped first end may form a flare to the main body and is particularly well suited for in ostium use. The first end is preferably self-expanding and the main body is preferably balloon-expandable. Also disclosed is a delivery device for delivering intraluminal ostial endoprosthetic devices, especially those disclosed herein, to a site for deployment. The delivery device may comprise an over-the-wire system or may comprise a rapid-exchange shuttle system. The self-expanding portion of the endoprosthesis is encapsulated in a sheath or other restraining apparatus on the delivery device. The balloon-expandable stent portion of the endoprosthesis is crimped onto a balloon delivery device.

Abstract: A portable data storage device (10) includes a universal serial bus (USB) coupling device (1) and an interface device (2) is coupled to the USB coupling device (1). The portable data storage device (10) also includes a memory control device (3) and a non-volatile solid-state memory device (4). The memory control device (3) is coupled between the interface device (2) and the memory device (4) to control the flow of data from the memory device (4) to the USB coupling device (1).

Abstract: Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of cytosolic serine hydroxymethyl transferase (cSHMT), T-box transcription factor 3 (Tbx3) and utrophin were aberrantly expressed in samples from cancer patients, as compared to samples from noncancer cases. Aberrant expression of proteins was validated by immunoblotting of plasma samples with specific antibodies to cSHMT, Tbx3 and utrophin. A cohort of 79 breast and 39 ovarian cancer patients, and 31 individuals who were either healthy or had noncancerous conditions was studied. We observed increased expression of truncated cSHMT, Tbx3 and utrophin in plasma samples obtained from patients at early stages of disease. The results indicate that cSHMT, Tbx3, utrophin and truncated forms thereof can be used as components of multiparameter monitoring of ovarian and breast cancer.

Abstract: The present invention relates to a new process for the preparation of new crystal modifications of esomeprazole non-salt form. Further, the present invention also relates to the use of said new crystal modifications for the treatment of gastrointestinal disorders, pharmaceutical compositions containing them as well as the crystal modifications, as such.

Abstract: An oral pharmaceutical dosage form comprising an acid susceptible proton pump inhibitor and one or more NSAIDs in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer. The fixed formulation is in the form of an enteric coating layered tablet, a capsule or a multiple unit tableted dosage form. The multiple unit dosage forms are most preferred. The new fixed formulation is especially useful in the treatment of gastrointestinal side-effects associated with NSAID treatment.

Abstract: The invention pertains to a coating composition, a coated material formed therewith, and a method for coating the material with the coating composition.

Abstract: A system and method provide the ability to collect, store and transmit information statements concerning satellite communication system use. The satellite system may collect billing information, such as roaming data, network use in terms of both total time and total bandwidth and functionality utilized on a user by user basis. Further, the satellite system may collect network usage information from the totality of users of a satellite system. The billing information and network usage information may be collected and stored on-board satellite(s) in a network in a data structure including a database. This information may then be collected, organized and transmitted to a variety of users in the earth segment of the system.

Abstract: The present invention relates to a novel form of the (?)-enantiomer of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2 -pyridinyl)-methyl]sulfinyl]-1H-benzimidazole, i.e. S-omeprazole. More specifically, it relates to a novel form of the magnesium salt of the S-enantiomer of omeprazole trihydrate. The present invention also relates to processes for preparing such a form of the magnesium salt of S-omeprazole and pharmaceutical compositions containing it. Furthermore, the present invention also relates to new intermediates used in the process.

Abstract: Systems and methods according to embodiment of the present invention prevent or otherwise mitigate data corruption and interference that may result when a communications on-the-move transmission is blocked by a radio relay link antenna transmitting on a shared frequency band. Harmful radiation that could affect persons blocking the line-of-sight of a COTM transmission is also prevented or mitigated. According to one embodiment of the present invention, if a building or other obstruction blocks the line-of-sight between a COTM antenna and a target satellite, the transmission will automatically cease, preventing or minimizing any potential interference that can occur, such as the interference to a radio relay link antenna operating atop a building. Similarly, persons who may have been in the line-of-sight will not be subjected to harmful radiation. COTM transmission remains offline until free line-of-sight is re-established.

Abstract: The invention relates to a multistation mixing device for mixing the contents of laboratory vessels. The device comprises at least two adapter plates having a holder for receiving laboratory vessels and a drive mechanism capable of driving the adapter plates in a mixing motion with the same angular speed such that, in horizontal planes, each point of the adapter plates performs a circular motion with the same radius, the same angle speed and the same angular position around a respective center. The starting positions of the adapter plates, from which the adapter plates are driven by the drive mechanism, are rotated relative to one another by an angle in the direction of the mixing motion in their respective angular position, such that imbalances occurring during the mixing motion are at least partially compensated.

Abstract: The present invention relates to the use of metabotropic glutamate receptor 5 antagonists for the inhibition of transient lower esophageal sphincter relaxations. A further aspect of the invention is directed to the use of metabotropic glutamate receptor 5 antagonists for the treatment of gastroesophageal reflux disease, as well as for the treatment of regurgitation.

Abstract: A film coating composition suitable for use in coating pharmaceutical formulations comprising a) an acrylic polymer dispersion, e.g. an ethylacrylate/methylmethacrylate copolymer such as Eudragit NE30D, b) a surfactant, c) sodium stearyl fumarate, and d) a water-containing liquid useful for the achievement of controlled release from pharmaceutical formulations such as tablets, pellets, etc.

Abstract: A system and method allow end users the ability to operate using non-compliant antennas. A coordination database may be continually updated with respect to geographic coordinates, time planning, frequency and orbital positions. Further, the system and method may utilize a tool for easily calculating interference resulting from the use of non-compliant antennas. These components, amongst others, spot possible slots in the frequency spectrum for non-compliance operations. A device may be integrated into terrestrial terminals to perform a sound, realistic and up-to-date interference calculation for equipment in a particular environment. The device may determine the level and extent of safety for operating the equipment in the particular environment.

Abstract: Data processing apparatus comprising: a processor core having means for executing successive program instruction words of a predetermined plurality of instruction sets; a data memory for storing program instruction words to be executed; a program counter register for indicating the address of a next program instruction word in the data memory; means for modifying the contents of the program counter register in response to a current program instruction word; and control means, responsive to one or more predetermined indicator bits of the program counter register, for controlling the processor core to execute program instruction words of a current instruction set selected from the predetermined plurality of instruction sets and specified by the state of the one or more indicator bits of the program counter register.