Abstract: A primary package containing a low molecular weight peptide-based thrombin inhibitors which package is sealed with a rubber stopper or plunger containing bromobutyl rubber.

Abstract: The invention features a method of identifying a candidate drug for treating functional dyspepsia. The invention also features a method of diagnosing a patient with functional dyspepsia.

Abstract: The present invention provides microporous photo quality glossy inkjet receiving media comprising a substrate, an absorbent basecoat layer, and an ink-receptive topcoat. The absorbent basecoat layer is primarily a combination of pigment and binder, and may include deformable particles, such as core-shell polymeric pigments. The ink-receptive topcoat is composed primarily of alumina hydrate, gelatin, and a water-insoluble cationic polymer. The present invention also provides a method for increasing the gloss and surface smoothness presented by the topcoat of a printing medium by including deformable particles in an underlying basecoat followed by calendering of the printing medium. Further, the present invention provides combination matte and gloss inkjet printing media, comprising matte basecoats at least partially coated with the aforementioned ink-receptive topcoat.

Abstract: A host system generates and manages databases incorporating data gathered from a plurality of client automation systems, such as CNC machine tools. The data may include real-time data, and is captured from the client systems under supervision of software downloaded over a network from the host system to the client systems. The captured data is transmitted over the network to the host, which creates the databases. The databases preferably include a commercial database comprising data associated with customer owners or operators of the client automation system, as well as a technical database, comprising captured data, administrative and other data, organized by customer and client system. Captured data is preferably associated with the date of capture, providing for the creation of a historical database for given client equipment. With customer authorization, others, such as original equipment manufacturers, may access the captured data, for which they may be charged a fee.

Abstract: The present invention relates to pharmaceutical formulations of an inhibitor of carboxypeptidase U (CPU) and a thrombin inhibitor in admixture with a pharmaceutically acceptable adjuvant, diluent or carrier, as well as a kit of parts, a method for treatment and use of the formulations for the treatment of a condition in which inhibition of CPU and/or inhibition of thrombin are required or desired.

Abstract: The invention provides a scintillation proximity assay for detecting peptidoglycan synthesis. The assay is especially suitable for high throughput screening of compounds affecting peptidoglycan synthesis.

Abstract: With this invention, expert knowledge from machine manufacturers is applied quickly at any time to a machine via the internet, by providing a main computer (host) for the production and provision of machine-related data and/or services and a machine-side working computer (client), which is connected to the main computer via a data communication link and (client) machine state data can be acquired in real time and transmitted to the main computer, and machine-related data and/or services generated by the main computer as a function of such machine state data can be received by an analysis and evaluation unit.

Abstract: The basic available command library of the run-time system (RTS1-RTS4) of a universal motion control (combined SPS/NC control) can be expanded dynamically and according to the user's specific requirements by loading technology packets TP (with corresponding technology object types TO). Thus, a dynamic scaling of a universal motion control UMC is possible. Due to a consistent integration and communication platform API, the functionality of extremely prepared technology packets TP can also be integrated into the control.

Abstract: In a method of monitoring the formation of a coating on a single particle (P), an apparatus is used which comprises means (2,5,6,9) for arranging said particle (P) at a given spatial location, and a fluid supply unit (3) adapted to apply a coating fluid to the particle (P) such that the coating is formed. Further, the apparatus has a measurement unit (4) which is adapted to perform a spectrometric measurement on the coating during formation thereof, and to derive a measurement value of at least one principle parameter related to the coating. This, such principle parameters, for example the thickness, thickness growth rate and physical and/or chemical properties related to the quality of the coating, as well as heat, mass and momentum transfer, can be continuously and non-invasively monitored during the coating process on the single particle (P).

Abstract: A method for operating automation control equipment applications ensures uninterrupted execution of a control application, at least during specific time periods, but such that the control application does not have the access privileges of a device driver. The operating system is configured for preventing calling of the processor commands from the control application, the processor communicating with the controlled automation equipment via a programmable bus interface. An embodiment of the method comprises the steps of performing read and write access of the control application to the bus interface directly and without routines of the operating system or device driver, and suspending processing of hardware interrupt calls of the processor during a preselected time period.

Abstract: Apparatus and method for on-wafer burn-in of a semiconductor device. In a preferred embodiment, the present invention is realized using an auto-prober commonly used in scan-testing of semiconductor devices. Specifically, in one embodiment, the auto-prober is programmed to sequentially apply an elevated current to each semiconductor device on a wafer. During the application of the elevated current, which substantially exceeds the normal operating current of the device, performance characteristics of the device, including its output power, is detected and registered. Preferably, each device is subjected to multiple scans by the elevated current. The device's performance characteristics is then analyzed. If a device exhibits consistent power output over different scans, it is not likely to suffer from infant mortality. If the device exhibits a shift in power output over successive scans, the device is likely to run into early failure and should be rejected.

Abstract: The present invention relates to nucleic acid molecules constituting GABAB receptor 1 promoters P1a and/or P1b, and to methods for screening for compounds which are modulators of GABAB receptor 1 transcription, said methods comprising the use of nucleic acid molecules constituting GABAB receptor P1a and/or P1b promoters.

Abstract: The present invention provides novel nucleic acid molecules coding for sigma subunits of Mycobacterium tuberculosis RNA polymerase. It also relates to polypeptides, referred to as SigA and SigB, encoded by such nucleic acid molecules, as well as to vectors and host cells transformed with the said nucleic acid molecules. The invention further provides screening assays for compounds which inhibit the interaction between a sigma subunit and a core RNA polymerase.

Abstract: An apparatus for use in sampling material on-line in a process system, comprising a sample collector (1) for receiving a sample of material, an elongate shaft (10) defining a passageway (14) carrying a measurement probe (11) for taking measurements from a collected sample, a pressurised fluid supply (31) connected to the passageway for delivering a pressurised fluid through the passageway to the sample collector for displacing the collected sample and a nozzle (33) provided at the distal end of the measurement probe (11) for distributing the pressurised fluid to the sample collector for displacing the collected sample from the sample collector (1).

Abstract: Novel compounds of formula (I) wherein R1 represents hydrogen; R2 represents hydroxy, fluoro, or an oxo group; R3 represents hydrogen; R4 represents hydrogen; and pharmaceutically acceptable salts, solvates, and the stereoisomers thereof, with the exception of the racemate of (3-amino-2-hydroxypropyl)sulphinic acid. The compounds are useful in therapy, especially for the treatment of reflux disease.

Abstract: Album pages for storing cards securely in place without slipping are disclosed. The album pages comprise a pocket located on a backing sheet. In a further embodiment, the pages comprise a sleeve located on the opposite side from the pocket. When a card mounted within the inventive album pages, the cards are securely retained within the pages and do not slide. The cards can be any type of generally flat items, such as photographs, greeting cards, invitations, or postcards. The invention also comprises an album page containing the inventive pages.

Abstract: The integration of a programmable logic controller (PLC) and a motion control (NC) into a universal motion control (UMC) is realized by a tailored and nonetheless essentially user-configurable run-level model for processing of software tasks. This run-level model consists of types of different user levels and system levels with different priorities. In particular, one of the run levels (FA) can be configured very effectively according to user requirements. Thus, this kind of universal motion control (UMC) can be optimized by software to the particular requirements of the control task and the technical process.