Patents Represented by Attorney Wiliam M. Blackstone

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  • Leukoregulin, an antitumor lymphokine, and its therapeutic uses
    Patent number: 4849506
    Abstract: Leukoregulin is identified, a biologically active lymphokine of molecular weight of about 120,000 to 140,000, with subunits of about 30,000 to 35,000, having the isoelectric focusing pH's of between 4.8 and 5.5 or between 7.5 and 8.3, which has the ability to regulate tumor cell physiology and growth without affecting the growth of normal cells. Methods for stimulating its production by monouclear cells, methods for its isolation and purification, and methods for its therapeutic uses are also disclosed.
    Type: Grant
    Filed: September 11, 1986
    Date of Patent: July 18, 1989
    Assignee: Akzo N.V.
    Inventors: Janet H. Ransom, Richard P. McCabe, Martin V. Haspel, Nicholas Pomato