Abstract: A first embodiment is a breast cancer prognosticator comprising a detection mechanism consisting a 15-gene signature. In addition there are embodiments comprised of 23-gene signatures and 28-gene signatures. The 28-gene signature may also be used for the prognosis of ovarian cancer. A second embodiment is a method to determine metastatic potential, relapse potential, or both in breast cancer patients comprising collecting a sample from an individual, removing marker-derived polynucleotide from said sample, using a detection mechanism to search for positive matches of said polynucleotides and either the 15, 23, or 28-gene signatures, and developing a quantitative expression profile. Utilizing risk analysis the individual can be placed into one of two or more groups predicting risk and/or clincopathogic variables.

Abstract: A method of creating a multi-phase fuel wherein said fuel comprises a gas, a solid, a liquid solvent phase and an aqueous phase from animal waste comprising the combination of the animal waste, a solvent, and a water/alcohol solution into a fluid mixture, placing the mixture into a closed reactor, heating said reactor between about 245° C. and 385° C. for between about 5 and 70 minutes and cooling said resulting multi-phase fuel. The animal waste may be manure, mortalities, municipal waste, or chicken litter. The preferred solvent is petroleum with the preferred petroleum being diesel fuel. The final multi-phase fuel can be separated into four separate fuels: a solid fuel, an emulsified solid in the liquid solvent phase by blending the solid, the solvent and a surfactant, an aqueous phase, and the recovered liquid solvent phase. Petroleum is the preferred solvent and the separation may be any conventional means. The mixture preferably consists of 1 part by weight animal waste, about 1.

Abstract: The present invention relates to the inhibition of the function of SHP2 by both anti-SHP2 peptides and the chemical compound 4-(2-sulfaminoethyl)benzoic acid, SEBA, and SEBA derivatives binding to the phosphotyrosyl phosphatase domain of SHP2 thereby inhibiting the function of SHP2 both in vitro and in vivo. In addition, the inhibition of SHP2 may be useful as a treatment for human disease, and it has been shown that interfering with SHP2 function using the anti-SHP2 peptides and SEBA compounds reverses cell transformation and induces remission of preformed tumors in vivo demonstrating a possible treatment for cancer.

Abstract: A method of making a liquid fuel from agricultural waste which may be animal manure, includes admixing agricultural waste with at least one material selected from the group consisting of hydrogen gas and water, at elevated pressure heating a mixture to about 300° C. to 400° C. for a predetermined time, subsequently cooling the mixture, and subsequently separating gas from liquid. The process produces a liquid fuel having a high heating BTU value per pound of fuel. The water preferably functions as both a solvent and the hydrogen donor for said agricultural waste. Corresponding apparatus is provided.

Abstract: A cleaning product comprising about 1% to 5% by weight cornstarch; about 17% to 27% by weight of an acid with a pH of about 2.5–3.5; about 52% to 62% by weight of a surfactant; about 7% to 17% by weight NaCl, wherein said cornstarch, said acid, said surfactant, and said NaCl are added together and heated to a slow bubbling boil and said cleaning composition appears smooth and milk-like in appearance and then heat reduced; and about 4% to 8% by weight oxalic acid dehydrate wherein said oxalic acid dehydrate is provided from the source manufactured under the tradename Barkeeper's Friend by SerVaas Laboratories of Indianapolis, Ind. and further wherein said compound is added after heat is reduced. The cleaning composition is useful for cleaning various types of metals.