Abstract: Substituted quinazolinones and pyridopyrimidines of structural formula I ##STR1## are angiotensin II antagonists useful in the treatment of disorders related to the renin-angiotensin system (RAS) such as hypertension, congestive heart failure, ocular hypertension and certain CNS disorders.
Type:
Grant
Filed:
July 31, 1992
Date of Patent:
October 26, 1993
Assignees:
Merck & Co., Inc., E. I. Du Pont De Nemours & Co.