Patents Represented by Attorney William Krouatin

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  • Alkenyl-substituted spirocyclic sulfamides as inhibitors of gamma-secretase
    Patent number: 7371771
    Abstract: Compounds of formula (I) are disclosed: wherein R4 is an alkenyl group of defined structure. The compounds inhibit gamma-secretase, and hence are useful for treatment of Alzheimer's disease.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: May 13, 2008
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Jose Luis Castro Pineiro, Joanne Claire Hannam, Timothy Harrison, Andrew Madin, Mark Peter Ridgill