Abstract: The present invention discloses a new immunogenic composition for Herpes Simplex comprising a whole live HSV-2 virus having the oncogene deleted. Methods of using the vaccine composition are also included.

Abstract: This invention provides a software-based method for determining the identity of a failed (hanging) channel in an array of multiple, buffered, synchronized data channels. A hanging channel may stem from a failed storage unit in the channel, a faulty connection within the channel, or a fault in the interface circuitry which connects the channel with the synchronization hardware. It is necessary and useful to identify a hanging channel in order to isolate it (as in a RAID 2-5 system) or for repair. The hanging channel is detected by examination of the byte content of the buffers. If the system is in a read mode, the buffer serving the hanging channel will contain substantially more bytes than the other buffers. If the system is in the write mode, the buffer serving the hanging channel will contain substantially fewer bytes than the other buffers.

Abstract: A recombinant virus (ICP10.DELTA.RR) has been developed which is useful in a Western blot assay to specifically detect antibody to HSV-2, even the presence of co-existing antibody to HSV-1.

Abstract: The present method relates to the serological detection of herpes simplex virus type 2 (HSV-2) infection by means of reaction of a patient serum with a peptide specific to HSV-2 having the sequence Ala-Arg-Ser-Pro-Glu -Arg-Gln-Glu-Pro-Arg-Glu-Pro-Glu. The peptide may be further modified by the addition of a Cys or a biotin molecule. The peptide may be used in any of a number of assays including enzyme linked immunosorbent assay (ELISA), a radioimmunoassay (RIA), and other forms of immunoassay such as enzyme immunoblotting assay on a suitable adsorbent paper or an agglutination assay using the peptide composition as the antigen.