Patents Represented by Attorney, Agent or Law Firm William Schmonsees
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Patent number: 6284578Abstract: A method of fabricating an IC device on a substrate comprising MOS transistors and other IC components. Each of the transistors of the IC device comprises a raised source electrode, a raised drain electrode, dual gate electrodes and self-aligned interconnect contact windows, and is connected to other transistors and other IC components through interconnects formed on top of such self-aligned contact windows.Type: GrantFiled: March 24, 2000Date of Patent: September 4, 2001Assignee: Mosel Vitelic, Inc.Inventor: Cheng-Tsung Ni
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Patent number: 5470582Abstract: A controlled release pharmaceutical composition comprising a physiologically active agent dispersed in preformed porous polymeric microparticles is provided. The active agent concentration may be up to about 10% by weight to achieve controlled release. Each of the porous microparticles has a plurality of preformed pores into which active agent is loaded and from which the active agent is subsequently released to the environment of use. The compositions are capable of delivering physiologically effective amounts of active agent for at least about thirty days, which delivery may be reversibly controlled by exposure to ultrasound.Type: GrantFiled: February 5, 1993Date of Patent: November 28, 1995Assignee: Syntex (U.S.A.) Inc.Inventors: Andreas Supersaxo, Jim H. Kou
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Patent number: 5366737Abstract: This invention relates to compounds of the formulaor an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, aralkyl of 7 to 11 carbon atoms, or when two or three of R.sup.3, R.sup.4, and R.sup.5 are taken together to form quinuclidino, piperidino, pyrrolidino, or morpholino; n is 1 to 8; and X is a pharmaceutically acceptable anion.Type: GrantFiled: February 10, 1993Date of Patent: November 22, 1994Assignee: Syntex (U.S.A.) Inc.Inventors: Deborah A. Eppstein, Philip L. Felgner, Thomas R. Gadek, Gordon H. Jones, Richard B. Roman
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Patent number: 5284971Abstract: Compounds of general formula (I) ##STR1## wherein R.sup.1 is (CH.sub.2).sub.n ((CHNR.sup.7 R.sup.8).sub.m C(O)R.sup.9 ; n=1-3; and m=0 or 1;R.sup.3 and R.sup.5 are independently Cl, Br, I, or CH.sub.3 ;R.sup.7 and R.sup.8 are independently H or (C.sub.1 -C.sub.4)alkyl;R.sup.9 is OH, (C.sub.1 -C.sub.4)alkoxy, or NR.sup.7 R.sup.8 ;R.sup.31 is H, Cl, Br, I, (C.sub.1 -C.sub.4)alkyl, (C.sub.4 -C.sub.6)cycloalkyl, (C.sub.1 -C.sub.4)haloalkyl, (C.sub.4 -C.sub.6)halocycloalkyl, or --CH(R.sup.10)Ar where Ar is selected from 5-hydroxypyrid-2-yl, 6-hydroxypyrid-3-yl, 6-hydroxypyridazin-3-yl, 6-methoxypyridazin-3-yl, 6-hydroxypyridazin-3-yl N-oxide, and 6-methoxypyridazin-3-yl N-oxide and R.sup.10 is H or (C.sub.1 -C.sub.4)alkyl;R.sup.41 is OH or a bioprecursor thereof; and the pharmaceutically acceptable salts thereof; are structural analogs of the thyroid hormones T.sub.3 and T.sub.4 and exhibit selective thyromimetic activity.Type: GrantFiled: July 16, 1992Date of Patent: February 8, 1994Assignee: Syntex (U.S.A.) Inc.Inventors: Keith A. Walker, Sharada S. Labadie, Denis J. Kertesz, Craig W. Laughton
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Patent number: 5232707Abstract: There is disclosed a process for the extraction of volatile solvents entrained in a polymer-based pharmaceutical composition designed for sustained release of drug over an extended period of time prepared in microcapsule form wherein the composition comprises at least one hormonally active water-soluble polypeptide in an effective amount greater than a conventional single dose and a biocompatible, bioerodable encapsulating polymer, which process comprises the steps of contacting the composition to a stream of dense gas, that is, pressurized gas and then removing the dense gas, and volatile solvents contained therein, extracted from the pharmaceutical composition.Type: GrantFiled: September 13, 1991Date of Patent: August 3, 1993Assignee: Syntex (U.S.A.) Inc.Inventor: David M. Lokensgard
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Patent number: 5212288Abstract: In a process for the solid phase synthesis of a polypeptide containing at least one serine residue, the improvement comprising temporarily protecting the side chain of the serine residue with a protecting group which is removed immediately following the addition of the serine to the peptide chain.Type: GrantFiled: February 8, 1991Date of Patent: May 18, 1993Assignee: Syntex (U.S.A.) Inc.Inventors: John J. Nestor, Jr., Natalie L. McClure, Humberto Arzeno
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Patent number: 5116817Abstract: The present invention relates to a novel nasal composition comprising a nona- or decapeptide having LHRH agonist or antagonist activity and a surfactant which is a bile acid or a pharmaceutically acceptable salt thereof in a buffered aqueous solution.Type: GrantFiled: September 20, 1990Date of Patent: May 26, 1992Assignee: Syntex (U.S.A.) Inc.Inventor: Shabbir T. Anik
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Patent number: 4883789Abstract: Compounds of the formula ##STR1## in which Ar is substituted or unsubstituted phenyl, pyridinyl, furanyl, naphthyl, thienyl, or thiazolyl; R is a (C.sub.1-4) alkyl; W is oxygen or methylene; and Ph is substituted or unsubstituted phenoxyphenyl, benzylphenyl, phenyliminophenyl, benzodioxolyl, or benzoylphenyl, exhibit pyrethroid-like insecticidal activity with low toxicity to aquatic fauna.Type: GrantFiled: February 9, 1987Date of Patent: November 28, 1989Assignee: FMC CorporationInventor: Scott M. Sieburth
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Patent number: 4818276Abstract: Novel aryltriazolinone compounds of the formula ##STR1## in which X is a chlorine or bromine atom and R is a radical selected from the group consisting of methyl, ethyl, 1-methylethyl, methoxymethyl, 2-methoxyethyl, 1-methyl-2-methoxyethyl, 2-propenyl, 2-propynyl, and 1-methyl-2-propynyl have herbicidal utility against a variety of grassy and broadleaf weeds in both preemergence and postemergence applications and show a selectivity favorable to cotton in preemergence applications.Type: GrantFiled: August 8, 1985Date of Patent: April 4, 1989Assignee: FMC CorporationInventors: Lester L. Maravetz, George Theodoridis
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Patent number: 4808762Abstract: Compounds of the formula ##STR1## in which Ar is substituted or unsubstituted phenyl, naphthyl, or thienyl; Z is oxygen, sulfur, or methylene; and Ar' is 2-methyl[1,1'-biphenyl]-3-yl, 3-phenoxyphenyl, 4-fluoro-3-phenoxyphenyl, or 6-phenoxy-2-pyridyl exhibit pyrethroid-like insecticidal and acaricidal activity and are relatively harmless to aquatic fauna.Type: GrantFiled: September 9, 1987Date of Patent: February 28, 1989Assignee: FMC CorporationInventors: Gary A. Meier, Scott M. Sieburth, Thomas G. Cullen, John F. Engel
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Patent number: 4806145Abstract: Herbicidal aryl triazolinones include the compounds of the formula ##STR1## where X is preferably halogen such as fluorine, Y is preferably halogen such as chlorine, R.sup.1 is preferably methyl, R.sup.2 is preferably CHF.sub.2, R.sup.3 is preferably CH(CH.sub.3). Z is oxygen or sulfur. R.sup.4 may be alkyl, substituted alkyl, alkenyl, alkynyl, monovalent cyclic having a ring of 5 or 6 atoms or ZR.sup.4 may be a residue of an amine, a sulfonamide, or an oxime.Type: GrantFiled: October 21, 1985Date of Patent: February 21, 1989Assignee: FMC CorporationInventor: Lester L. Maravetz
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Patent number: 4787931Abstract: N-phenyl-N'-(pyridinyl-N-oxide)ureas of the formula ##STR1## and their use as plant regulators are disclosed and exemplified.Type: GrantFiled: June 17, 1986Date of Patent: November 29, 1988Assignee: FMC CorporationInventors: Robert Henrie, II, Christine M. Green, Robert E. Sticker
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Patent number: 4767779Abstract: Pyrazolines of the following formula are insecticides: ##STR1## wherein R.sub.A, R.sub.B and R.sub.C are aromatic groups; R.sub.N is hydrogen or lower alkyl; and W is oxygen or sulfur.Type: GrantFiled: April 9, 1986Date of Patent: August 30, 1988Assignee: FMC CorporationInventor: Angelina J. Duggan
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Patent number: 4766233Abstract: Herbicidal utility for 2-aryl-1,2,4-triazine-3,5(2H,4H)-diones and sulfur analogs is disclosed and exemplified. Many of the disclosed compounds are novel. Methods for preparing the herbicidal compounds and intermediates therefor are also disclosed.Type: GrantFiled: December 12, 1985Date of Patent: August 23, 1988Assignee: FMC CorporationInventor: John W. Lyga
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Patent number: 4743291Abstract: Herbicidal aryl triazolinones include the compounds of the formula ##STR1## where X is preferably halogen such as fluorine, Y is preferably halogen such as chlorine, R.sup.1 is preferably methyl, R.sup.2 is preferably CHF.sub.2, R.sup.3 is preferably CH(CH.sub.3), and ##STR2## is --NH.sub.2 or the residue of a primary or secondary amine or of a sulfonamide.Type: GrantFiled: May 5, 1986Date of Patent: May 10, 1988Assignee: FMC CorporationInventor: Lester L. Maravetz
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Patent number: 4742176Abstract: An improved process for the manufacture of herbicidal 2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone by cyclizing 3-chloro-N-hydroxy-2,2-dimethylpropanamide with an alkaline or alkaline earth hydroxide at a pH of 7.5 to 9.5, benzylating the resulting 4,4-dimethyl-3-isoxazolidinone, eliminating by-product 1-[(2-chlorophenyl)methoxy]-3,3-dimethyl-2-azetidinone by contacting the product mixture with anhydrous hydrogen chloride, and further benzylating free isoxazolidinone with base.Type: GrantFiled: February 14, 1986Date of Patent: May 3, 1988Assignee: FMC CorporationInventors: Mariano A. Guiducci, Matthew I. Levinson
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Patent number: 4740637Abstract: Disclosed and examplified is a general method for producing methylol compounds by the reaction of an organometallic compound with formaldehyde in which the formaldehyde is generated in situ from and by the use of a high molecular weight linear formaldehyde homopolymer.Type: GrantFiled: December 2, 1986Date of Patent: April 26, 1988Assignee: FMC CorporationInventors: Eric G. DelMar, Charles T. Kwiatkowski
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Patent number: 4737509Abstract: Compounds of the formula ##STR1## wherein Z is ##STR2## compositions containing the compounds, and their utility as dietary and foliar insecticides are disclosed and exemplified.Type: GrantFiled: December 4, 1986Date of Patent: April 12, 1988Assignee: FMC CorporationInventor: Ernest L. Plummer
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Patent number: 4709068Abstract: Compounds containing a dimethylsilane core and a phenoxybenzyl substituent are found to exhibit pyrethroid-like activity toward insects with low toxicity to fish.Type: GrantFiled: June 2, 1986Date of Patent: November 24, 1987Assignee: FMC CorporationInventor: Scott M. Sieburth
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Patent number: 4692182Abstract: Isoxazolidinones of the following formula are herbicides: ##STR1## or an agriculturally acceptable salt thereof in which R.sub.1 and R.sub.2 are independently selected from -hydrogen and-halogen; and R.sub.Type: GrantFiled: May 19, 1986Date of Patent: September 8, 1987Assignee: FMC CorporationInventor: Jun H. Chang