Abstract: The invention provides tktA polypeptides and polynucleotides encoding tktA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tktA polypeptides and polynucleotides to screen for antibacterial compounds and for the detection of Streptococcus pneumoniae.
Type:
Grant
Filed:
April 23, 1999
Date of Patent:
December 4, 2001
Assignee:
SmithKline Beecham Corp.
Inventors:
Alison F Chalker, Sauli J Haataja, David W Holden, David J Holmes, Karen A Ingraham, Gee W Lau, Andrea Marra, Michael A Lonetto, Damien McDevitt, Jennifer Ray, Jun Yu