Patents Represented by Attorney William T. Teoli, Jr.

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  • Process for the preparation of ste specific 1'-spiro-nucleosides
    Patent number: 5714599
    Abstract: The invention relates to a novel process for stereocontrolled preparation of 1',1'-disubstituted and 1'-spiro-nucleosides of the formula I ##STR1## in which the substituents A, R.sub.8 and R.sub.9 are as defined in claim 1, and to novel intermediates and their use in this process and to processes for the preparation of the novel intermediates. The process is illustrated by the example of biologically active (+)-hydantocidin.
    Type: Grant
    Filed: June 24, 1994
    Date of Patent: February 3, 1998
    Assignee: Novartis Corporation
    Inventor: Philippe Chemla