Patents Represented by Attorney, Agent or Law Firm Willliam J. Davis
  • Patent number: 6624307
    Abstract: Commercially viable process for producing 2,6-dihydroxy-3,4-dimethlpridine. The process includes reacting 2-cyanoacetamide with sodium methoxide followed by condensation with ethyl 2-methylacetoacetate in methanol to give the sodium salt of 2,6-dihydroxy-4,5-dimethyl-3-pyridinecarbonitrile. The sodium salt of 2,6-dihydroxy-4,5-dimethyl-3-pyridinecarbonitrile is hydrolyzed with hydrobromic acid and decarboxylated to the hydrobromide salt of 2,6-dihydroxy-3,4-dimethylpyridine. The desired 2,6-dihydroxy-3,4-dimethylpyridine is produced from the hydrobromide salt by neutralizing the same with sodium hydroxide.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: September 23, 2003
    Assignee: ISP Investments Inc.
    Inventors: Murugappa Vedachalam, Jon Kirk Smith