Patents Represented by Attorney Wilmer Cutler Pickering Hale & Dorr LLP
  • Patent number: 8202846
    Abstract: The present invention provides methods for attenuating gene expression in a cell, especially in a mammalian cell, using gene-targeted double stranded RNA (dsRNA), such as a hairpin RNA. The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the “target” gene).
    Type: Grant
    Filed: November 23, 2004
    Date of Patent: June 19, 2012
    Assignee: Cold Spring Harbor Laboratory
    Inventors: Gregory J. Hannon, Patrick Paddison, Emily Bernstein, Amy Caudy, Douglas Conklin, Scott Hammond
  • Patent number: 8201796
    Abstract: A corner protector comprising a guard, strap, and plate or rod are disclosed. The first portion and second portion of the guard are substantially orthogonal to the top portion, and to each other. The first portion and second portion meet to define a corner protrusion. The guard has interior extending ribs that are substantially vertical and maintain contact with the guard. The strap has at least one connection member on each end to allow the corner protector to be adjusted vertically. The plate or rod has at least one locking member for creating a locking mechanism with the connection member.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: June 19, 2012
    Assignee: Rhoost, LLC.
    Inventors: Vianka Perez Belyea, Tavinder Phull, Graeme Wagoner-Lynch
  • Patent number: 8200830
    Abstract: Systems and methods are provided to allow detection of the load conditions on network devices. The load detection can occur using a mobility management device to track establishment of sessions and attempts at session establishment to determine the loading conditions on various network devices. This information can then be used by a selection logic to determine which devices are selected to send session establishment messaging for new session establishment requests. This can provide quicker setup times as highly loaded network devices or network devices experiences other failures are selected less until conditions are back to normal.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: June 12, 2012
    Assignee: Cisco Technology, Inc.
    Inventors: Rajesh Ramankutty, Kuntal Chowdhury, Andrew Gibbs
  • Patent number: 8199595
    Abstract: Techniques for sensing a semiconductor memory device are disclosed. In one particular exemplary embodiment, the techniques may be realized as an apparatus including a memory cell array comprising a plurality of memory cells. The apparatus may also include a first data sense amplifier circuitry including an amplifier transistor having a first region coupled to at least one of the plurality of memory cells via a bit line. The apparatus may further include a data sense amplifier latch circuitry including a first input node coupled to the data sense amplifier circuitry via a second region of the amplifier transistor.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: June 12, 2012
    Assignee: Micron Technology, Inc.
    Inventors: Philippe Bruno Bauser, Jean-Michel Daga
  • Patent number: 8194698
    Abstract: Methods and systems are provided for updating the quality of service (QoS) of an IP flow in a wireless communications system. More particularly, the methods and systems provide the ability to update a QoS grant from any level of QoS to any other level of QoS, from no QoS to some level of QoS, and from some level of QoS to no level of QoS. The update of QoS can be based, at least in part, on a request being made for an updated QoS. A decision is made whether or not to update the QoS; and depending on the decision, the QoS can be updated.
    Type: Grant
    Filed: August 7, 2006
    Date of Patent: June 5, 2012
    Assignee: Cisco Technology, Inc.
    Inventors: Janakiraman Senthilnathan, Kuntal Chowdhury
  • Patent number: 8195661
    Abstract: A method and apparatus for storing data on application-level activity and other user information to enable real-time multi-dimensional reporting about a user of a mobile data network. A data manager receives information about application-level activity from a mobile data network and stores the information to provide dynamic real-time reporting on network usage. The data manager comprises a database, data processing module, and analytics module. The database stores the application-level data for a predetermined period of time. The data processing module monitors the data to determine if it corresponds to a set of defined reports. If the data is relevant, the processing module updates the defined reports. The analytics module accesses the database to retrieve information satisfying operator queries about network usage. If the operator chooses to convert the query into a defined report, the analytics module creates a newly defined report and populates it accordingly.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: June 5, 2012
    Assignee: Umber Systems
    Inventor: Asawaree Kalavade
  • Patent number: 8196203
    Abstract: Aspects of the invention relate to a method, apparatus, and computer readable medium for determining software trustworthiness. In some examples, a software package identified as including at least one file of unknown trustworthiness is installed on a clean machine. A report package including a catalog of files that have been installed or modified on the clean machine by the software package is generated. Identification attributes for each of the files in the catalog is determined. Each of the files in the catalog is processed to assign a level of trustworthiness thereto. The report package is provided as output.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: June 5, 2012
    Assignee: Symantec Corporation
    Inventor: Pieter Viljoen
  • Patent number: 8194487
    Abstract: A semiconductor device along with circuits including the same and methods of operating the same are described. The device comprises a memory cell including one transistor. The transistor comprises a gate, an electrically floating body region, and a source region and a drain region adjacent the body region. Data stored in memory cells of the device can be refreshed within a single clock cycle.
    Type: Grant
    Filed: September 17, 2008
    Date of Patent: June 5, 2012
    Assignee: Micron Technology, Inc.
    Inventors: Eric Carman, Mikhail Nagoga, Serguei Okhonin
  • Patent number: 8191479
    Abstract: A reduced collateral damage bomb (RCDB) bomb casing is described and disclosed along with the system and method for making it. The RCDB bomb casing may be formed from conventional or penetrating warhead bomb casings. The RCDB bomb casing has a filler material/materials disposed on the interior walls that will assist in controlling the collateral damage caused by the finished bomb but not prevent the appropriate destructive power being delivered to a selected target. Further, the fusing system may include a shaped charge to control the ignition of the main explosive charge to control the amount of collateral damage when the bomb casing is filled with high explosives.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: June 5, 2012
    Inventors: James D. Ruhlman, Blake K. Thomas
  • Patent number: 8187735
    Abstract: Electroactive compositions are disclosed for use in lithium ion battery electrodes. The compositions, such as multifunctional mixed metal olivines, provide an electrochemical cell having a plurality of open circuit voltages at different states of charge. The compositions afford improved state-of-charge monitoring, overcharge protection and/or overdischarge protection for lithium ion batteries.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: May 29, 2012
    Assignee: A123 Systems, Inc.
    Inventors: Yet-Ming Chiang, Andrew C. Chu, Young-Il Jang, Nonglak Meethong, Yu-Hua Kao, Gilbert N. Riley, Jr., Anthony E. Pullen, Karen E. Thomas-Alyea
  • Patent number: 8187753
    Abstract: Materials useful as electrodes for lithium batteries have very good electronic and ionic conductivities. They are fabricated from a starting mixture which includes a metal, a phosphate ion, and an additive which enhances the transport of lithium ions in the resultant material. The mixture is heated in a reducing environment to produce the material. The additive may comprise a pentavalent metal or a carbon. In certain embodiments the material is a two-phase material. Also disclosed are electrodes which incorporate the materials and lithium batteries which incorporate those electrodes.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: May 29, 2012
    Assignee: A123 Systems, Inc.
    Inventors: Michael Wixom, Chuanjing Xu
  • Patent number: 8189376
    Abstract: An integrated circuit device (e.g., a logic or memory device) having a memory section including a plurality of memory cells, wherein each memory cell thereof includes at least one n-channel transistor having a gate, gate dielectric and first, second and body regions, wherein the gate of the at least one n-channel transistor of each memory cell includes one or more gate materials, disposed on or over the gate dielectric material. The one or more gate materials may include a semiconductor material having one or more acceptor-type doping species disposed therein. The integrated circuit device may further include a logic section including at least one n-channel transistor having a gate, gate dielectric and first, second and body regions, wherein the gate of the n-channel transistor of the logic section may include a gate semiconductor material disposed on or over the gate dielectric material.
    Type: Grant
    Filed: February 2, 2009
    Date of Patent: May 29, 2012
    Assignee: Micron Technology, Inc.
    Inventor: Viktor Koldiaev
  • Patent number: 8190755
    Abstract: Method and apparatus for host authentication in a network implementing network access control is described. In an example, a network access control (NAC) server receives network address requests from hosts on a network. If a host is compliant with an established security policy, the NAC server determines a unique indicium for the host and records the unique indicium along with a network address leased to the host by a dynamic host configuration protocol (DHCP) server. When a host requests access to a resource on the network, the host is authenticated by determining whether its asserted network address is valid. If valid, a pre-computed unique indicium for that address is obtained and compared with a unique indicium for the host. If the indicia match, the host is allowed access to the resource. Otherwise, the host is blocked from access to the resource.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: May 29, 2012
    Assignee: Symantec Corporation
    Inventors: Sourabh Satish, Brian Hernacki, Shane Pereira
  • Patent number: 8188112
    Abstract: The invention relates to compounds for use in medicine.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: May 29, 2012
    Assignee: Agency for Science, Technology and Research
    Inventors: Surana Uttam, Vaidehi Krishnan, Anthony Ting, Hong Hwa Lim
  • Patent number: 8190732
    Abstract: A method and apparatus for providing information associated with service providers using a social network is described. In one embodiment, a method of providing indicia of familiarity with the service providers comprises identifying one or more relationships between one or more service providers and a user using a social network associated with the user and generating information regarding the one or more relationships, wherein the information comprises a social distance between the user and each service provider of the one or more service providers where the social distance represents an indicia of familiarity between the user and each service provider of the one or more service providers.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: May 29, 2012
    Assignee: Symantec Corporation
    Inventors: Shaun Cooley, Keith Newstadt, Laura Garcia-Manrique, Sourabh Satish, Brian Hernacki, Timothy G. Brown
  • Patent number: 8191078
    Abstract: A fault-tolerant messaging system comprises a primary broker, a first network, a back up broker, and a second network. The primary broker and the back up broker are coupled to the first network for communication with clients thus creating a messaging system. The primary broker and the back up broker are also coupled to the second network for replicating state from the primary broker and the back up broker, and also sending transaction events immediately to maintain synchronization. The brokers further comprise a replication module for communicating state between the primary broker and the back up broker, a recovery module for performing recovery on the back up broker upon failure of the primary broker, and a fault-tolerant connection module for establishing a fault-tolerant connection between the primary broker and the back up broker over the second network. The present invention also includes a number of novel methods for performing fault tolerance.
    Type: Grant
    Filed: March 22, 2005
    Date of Patent: May 29, 2012
    Assignee: Progress Software Corporation
    Inventors: William M. Cullen, Peter S. Easton, Ling-Yun Yin, Michael E. Theroux, Giovanni Boschi, Colin W. MacNaughton, Ronald F. Rudis
  • Patent number: 8184858
    Abstract: A system and method are described for selecting and identifying a unique object or feature in the system user's three-dimensional (“3-D”) environment in a two-dimensional (“2-D”) virtual representation of the same object or feature in a virtual environment. The system and method may be incorporated in a mobile device that includes position and orientation sensors to determine the pointing device's position and pointing direction. The mobile device incorporating the present invention may be adapted for wireless communication with a computer-based system that represents static and dynamic objects and features that exist or are present in the system user's 3-D environment. The mobile device incorporating the present invention will also have the capability to process information regarding a system user's environment and calculating specific measures for pointing accuracy and reliability.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: May 22, 2012
    Assignee: Intelligent Spatial Technologies Inc.
    Inventor: David Caduff
  • Patent number: 8182473
    Abstract: Photocosmetic device for use in medical or non-medical environments (e.g., a home, barbershop, or spa), which can be used for a variety of tissue treatments. Radiation is delivered to the tissue via optical systems designed to pattern the radiation and project the radiation to a particular depth. The device has a variety of cooling systems including phase change cooling solids and liquids to cool treated skin and the radiation sources. Contact sensors and motion sensor may be used to enhance treatment. The device may be modular to facilitate manufacture and replacement of parts.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: May 22, 2012
    Assignee: Palomar Medical Technologies
    Inventors: Gregory B. Altshuler, Joseph P. Caruso, Henry H. Zenzie, James G. Burke, III, Andrei V. Erofeev
  • Patent number: RE43473
    Abstract: A needle assembly includes a needle and a hub mounted to each other. The hub includes a sidewall spaced outwardly from the needle cannula and extending to a distal position between the opposed ends of the needle cannula. A housing integral with the hub defines a sidewall to partially confine a safety shield. The safety shield is slidably disposed about the needle cannula and releasably retained in a proximal position and can be moved to a distal position where the safety shield completely surrounds that portion of the needle hub projecting distally from the hub. The needle assembly includes a spring for propelling the safety shield to the distal position and a latch for releasing the safety shield from the proximal position. The latch may be passively activated by normal usage of the medical implement to which the needle assembly is mounted or alternately activated manually.
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: June 12, 2012
    Assignee: Becton, Dickinson and Company
    Inventors: C. Mark Newby, Michael Bennett, Hugh T. Conway, Bradley M. Wilkinson, John Hitchings
  • Patent number: D662044
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: June 19, 2012
    Assignee: Third Rail Mobility, LLC.
    Inventors: Brian Lemelman, Alexandra Lemelman, David Lemelman