Patents Represented by Attorney, Agent or Law Firm Wilson Sonsini Goodrich & Rosati Shirley Chen
  • Patent number: 6509370
    Abstract: A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: water and micelles comprising paclitaxel and a pharmaceutically-acceptable, water-miscible solubilizer forming the micelles, the solubilizer selected from the group consisting of solubilizers having the general structures R1COOR2, R1CONR2, and R1COR2, wherein R1 is a hydrophobic C3-C50 alkane, alkene or alkyne and R2 is a hydrophilic moiety. The solubilizer is selected such that it does not have a pKa less than about 6.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: January 21, 2003
    Assignee: SuperGen, Inc.
    Inventors: Rajashree Joshi-Hangal, Ashok Y. Gore, Joseph Rubinfeld, Rajesh Shrotriya