Abstract: The present invention is directed to uricase modified with polyethylene glycol and to methods of treating different illnesses characterized by increased circulating uric acid levels, including but not limited to, hyperuricemia and tumor lysis syndrome.
Type:
Grant
Filed:
August 2, 2001
Date of Patent:
July 5, 2005
Assignee:
Phoenix Pharmacologics, Inc.
Inventors:
Charles Mark Ensor, Mike A. Clark, Frederick Wayne Holtsberg