Abstract: An emulation system functions to translate instructions comprising a target application of a target system into corresponding instructions native to a host system and executes the instructions on the host system. During execution, the emulation system encounters target disk read/write operations. As the memory architectures of the host and target computer systems differ, the data in host memory is conformed to a target memory format when data in keyboard memory buffer is processed. Also, the host and target disk controllers cause storage of data on diskettes in differing byte orders. However, the emulation system performs disk/read write operations without byte-reversal prior to disk-write or subsequent to disk read operations. Thus, the host does not produce storage media having data conforming to that of target storage media.

Abstract: Disclosed herein are non-endogenous, constitutively activated forms of the human 5-HT2A and human 5-HT2C receptors and uses of such receptors to screen candidate compounds. Further disclosed herein are candidate compounds identified by the screening method which act at the 5HT2A receptors. Yet further disclosed is a new class of compounds which act at the 5HT2A receptors.

Abstract: Disclosed herein are quinoline derivatives having dual mechanistic properties, referred to in this patent document as “acetylcholine enhancers”, i.e., compounds which evidence acetylcholinesterase (AChE) inhibition activity, and 5-HT3 receptor antagonist activity. A particularly preferred compound is 2-[2-(1-benzylpiperizin-4-yl) ethyl]-2,3-dihydro-9-methoxy-1H-pyrrolo [3,4-b] quinolin-1-one hemifumarate, referred to herein as Compound A (“Cm.A”).

Abstract: Drink bottles are provided having improve sanitation. In accordance with the preferred feature of the invention, a barrier is disposed around the spout of a squeezable drink bottle so as to inhibit contact between the end of the spout from which liquid is expressed and the lips of a person receiving liquid from a bottle. Elimination of reflux and improved sanitation results.