Patents Represented by Attorney Yi Li
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Patent number: 7934624Abstract: The invention serves to simultaneously pour out two separate liquids with a specified quantitative ratio from a container. To this end, a separate container is located inside said container. The container closure forms a mouth cap (1). This tapers upward conically into a straight concentric spout (2) with an interior space (11). A larger, closeable spout neck (4) having a projection (5) that radially projects at the bottom is placed concentrically around the straight spout (2) of the mouth cap (1). This projection (5) is supported with supporting braces (6) an the shoulder (7) formed by the conical taper. A flow opening (9), which encircles up to the supporting braces (6), is left open between the shoulder (7) and the inside edge (8) of the projection (5) and of the larger spout neck (4). The supporting braces (6) and the radial projection (5) are each passed through by a borehole (10) that communicate with the inside of the mouth cap (1) and with the space (16) outside the larger spout neck (4).Type: GrantFiled: November 7, 2006Date of Patent: May 3, 2011Assignee: Belcap Switzerland AGInventor: Fritz Seelhofer
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Patent number: 7922806Abstract: A process of producing a kaolin product for paper coating includes mining kaolin ores by hydromechanization and then producing kaolin slurry; classifying by centrifugal sedimentation; chemical bleaching; eliminating iron ions by circular rinsing; removing water by pressure filtration; producing slurry by dispersing filter cakes, in which complex dispersants, pH adjustor and intercalator are added; delaminating; classifying by vibrating sieve; and spray drying: spray driers are restructured by adding insulating layers on packing auger, elevator scoop and bunker at first; the kaolin slurry J which has passed through vibrating sieves is dried in high speed centrifugal spray drying tower and the moisture of kaolin powder is controlled in 3 wt. %-5 wt. %, and the kaolin product for paper coating is obtained. The process characterizes in stable properties, high efficiency, and high viscosity content and fine particle size of the kaolin products produced.Type: GrantFiled: August 3, 2008Date of Patent: April 12, 2011Assignees: China University of Geosciences (Wu Han), Maoming Petrochemical Mining Co., Ltd.Inventors: Chunjie Yan, Xiaoyan Zhu, Jieyu Chen, Shujie Hai, Jielin Xu, Xiaoming Chen, Yizhi Cui, Weiqing Zeng
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Patent number: 7897640Abstract: Medicaments containing shikonin compounds and salts thereof including shikonin and alkannin are used for treatment of virus infections, mycoplasma infections and malignant tumor.Type: GrantFiled: September 26, 2007Date of Patent: March 1, 2011Assignee: Beijing JBC Chinese Traditional Medicine Science and Technology Develop Co. LtdInventor: Feixin Wang
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Patent number: 7896155Abstract: The invention relates to a capsule closure, the cap of which comprises a receptacle (2) that is formed on the interior of the lid and that fits into the interior of a corresponding nipple part (3). An associated film-sealed container capsule (8) can be locked into the interior of the receptacle (2), with the film facing downwards (9), so that the sealing film (9) lies against the inner diameter of the cap (1). A circular shoulder that projects inwards (10) is configured in the interior of the nipple part (3) below the inserted container capsule (8). Several fixed and/or displaceable piercing and/or cutting elements (12) are formed on the inner edge (11) of said shoulder (10). A tamper-evident strip (15) is supported on a shoulder (17) that projects radially outwards below the lower cap edge of the attached cap (1). Once said strip has been removed, the cap (1) can be pushed down onto the nipple part (3), causing the piercing and/or cutting elements (12) to cut open the film (9).Type: GrantFiled: September 28, 2005Date of Patent: March 1, 2011Assignee: Belcap AGInventor: Fritz Seelhofer
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Patent number: 7886922Abstract: The invention relates to a plastic closing device comprising a bottom part, a closing cap, and a cutting ring which is mounted inside the neck of the bottom part so as to be helically movable. A driving cam (16) which is axially disposed in the closing cap acts upon the non-continuously circular cutting ring when the closing cap is unscrewed such that the cutting ring perforates and cuts through the receptacle in a helical cutting movement. The cutting ring forms a ventilating concavity (6) which cooperates with the driving cam (16). The non-circular cutting ring, the bottom side of which is provided with a sharp cutting edge extending at an obtuse angle relative to the bottom edge of said ring, performs a helical cutting movement similar to an advancing knife when the closing cap is unscrewed such that the receptacle wall is easily cut by applying a minimum amount of force because a new sharp point constantly attacks the packaging material, thus preventing shredding.Type: GrantFiled: January 29, 2007Date of Patent: February 15, 2011Inventor: Fritz Seelhofer
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Patent number: 7880328Abstract: A stage-fused underground transformer loop system, which includes a series of transformers connected sequentially by a series of cables, and a series of fused elbow terminators connected to the inlets and outlets of the transformers. The fused elbow terminators are arranged in an order of decreasing the fuse capacity starting from the feed. The fused elbow terminator includes an elbow connector having a housing and a cable connector disposed within; and a fused pin connected to the cable connector. Further disclosed is a method of rapid diagnosis of a fault cable or a transformer failure using the stage-fused transformer loop system.Type: GrantFiled: October 21, 2008Date of Patent: February 1, 2011Inventor: Gregory P. Whyte
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Patent number: 7794703Abstract: A method for production and delivery of a protein in vivo is described. The method includes steps of inserting a promoter and a gene encoding a protein in a vector, collecting an amount of host cells from a mammal, treating the host cells in vitro with the vector, then introducing the treated cells back to the mammal. In vivo, the treated host cells produce red blood cells and the protein which is contained in the red blood cells. The protein is released into peripheral blood of the mammal through a natural or an induced rupture of the red blood cells to supply the protein to the body.Type: GrantFiled: December 9, 2009Date of Patent: September 14, 2010Inventor: Hai Xing Chen
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Foot-bath agent of Chinese herbal medicine for regulating blood pressure and improving sleep quality
Patent number: 7754251Abstract: The present invention relates to a foot-bath agent for regulating blood pressure and improving sleep quality, which includes fructus leonuri 20-25%, semen ziziphi spinosae 15-20%, calcined magnetitum 17-22%, spica prunellae 15-20%, ligusticum chuanxiong hort 18-23%, and borneolum 0.7-1.2% by weight. The foot-bath agent has advantages including no allergy and less side effects to human body.Type: GrantFiled: September 11, 2008Date of Patent: July 13, 2010Inventor: Guangjun Zhao -
Patent number: 7686071Abstract: A condenser includes a condenser core, input and output manifolds connected therewith. The condenser core has a blade-thru structure, which is formed by a plurality of layers of thin metal blades stacked on top of another by joint interfaces or joined by spacer rings between two adjacent blades. Each layer of the blades includes condensation chamber(s), wherein the floor of the chamber is monolithic with the rest of the blade. The blades are so aligned that the condensation chamber(s) of each blade are on top of the condensation chamber(s) of the blade immediate underneath, thereby forming phase exchange column(s). Each condensation chamber has one or more apertures on the floor thereof, permitting vapor and condensate to pass therethrough and causing vibration of the chamber floor. Further disclosed is a heat dissipation system utilizing the blade-thru condenser, as well as a computer system utilizing the heat dissipation system.Type: GrantFiled: July 27, 2006Date of Patent: March 30, 2010Assignee: ArticChoke Enterprises LLCInventor: Paul Silverstein
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Patent number: 7597794Abstract: The present invention is a separation method and system in which granulation of coupled post-extraction asphalt residue is used to achieve deep separation of heavy oil. A dispersion solvent is introduced into the asphalt phase after separation by solvent extraction and the asphalt phase undergoes rapid phase change in a gas-solid separator and is dispersed into solid particles while the solvent vaporizes, resulting in low temperature separation of asphalt and solvent with adjustable size of the asphalt particles. The separation method of this invention also includes a three-stage separation of heavy oil feedstock, in which the deasphalted oil phase separated from heavy oil is treated with supercritical solvent and results in the further separation of the resin portion of the deasphalted oil, maximizing the yield and quality of the deasphalted oil.Type: GrantFiled: November 1, 2005Date of Patent: October 6, 2009Inventors: Suoqi Zhao, Chunming Xu, Ren′an Wang, Zhiming Xu, Xuewen Sun, Keng H. Chung
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Patent number: 7572437Abstract: Compositions, kits and methods are provided for Interferon analogs in order to promote general health or for therapeutic treatment of diseases. Human interferon analogs are made by fusion of interferon with human serum albumin. The bio-assay shows that the interferon analogs with the same cell protection against viral attack have 3-10 times longer acting function than interferon in vivo. These novel long acting interferon analogs can be used in treatment of patients with viral infection, such as SARS virus, HIV, HCV, HBV, or HAV, and the cancer diseases, such as leukemia and malignant melanoma. They also have a 3-5 times longer shelf-life compared with interferon.Type: GrantFiled: May 24, 2004Date of Patent: August 11, 2009Inventors: Yan Fu, Zailin Yu
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Patent number: 7544474Abstract: A method for sequentially detecting multiple target nucleic acid fragments in a sample includes steps of adding a sample into a column having a test snare which has thereon two or more single strand capture DNA sequences; wherein each capture sequence binds specifically with one target nucleic acid fragment, and forms a double strand segment; washing out unbound target nucleic acid fragment; adding a first DNA probe, which has thereon a chemical label, to attach specifically to a probe binding site of the first target nucleic acid fragment; washing out unbound first probe; adding a triggering solution to trigger the chemical label; and detecting signals on the test snare for determining the first target nucleic acid fragment; subsequently, adding a second DNA probe to bind specifically to the second target nucleic acid fragment; washing, triggering and detecting signals for determining the second target nucleic acid fragment in the same manner.Type: GrantFiled: March 23, 2007Date of Patent: June 9, 2009Assignee: ACGT Medico Inc.Inventor: Hai Xing Chen
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Patent number: 7482122Abstract: A method of enhancing detection signal for measurement of nucleic acid sequences includes providing a T- or L-primary probe having a target-binding segment and an enhancer linker segment; and hybridizing the primary probe with a target sequence of interest; providing a first enhancement probe having a first annealing segment complementary to the enhancer linker segment, a second annealing segment and a chemical label; hybridizing the first enhancement probe to the primary probe; providing a second enhancement probe having a first annealing segment complementary to the second annealing segment of the first enhancement probe, a second annealing segment complementary to the first annealing segment of the first enhancement probe, and the same chemical label; hybridizing the first and second enhancement probes, thereby multiple first and second enhancement probes annealing with each other forming a staggered chain extending from the primary probe; and detecting the chemical labels in the final complex.Type: GrantFiled: October 19, 2005Date of Patent: January 27, 2009Inventor: Hai Xing Chen
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Patent number: 7465453Abstract: Polypeptides having an amino acid sequence of SEQ ID NO: 2, and having amino acid residues 9 to 27 of SEQ ID NO: 2 are disclosed, which are together named C-terminal polypeptides of CKLF1. Also disclosed is a pharmaceutical composition containing a therapeutically effective amount of the CKLF1 C-terminal polypeptide and pharmaceutically acceptable salts, carrier or excipient. Further disclosed are the polynucleotides encoding the C-terminal polypeptides of CKLF1, and vectors and host cells containing the polynucleotides; the in vitro assays for detecting the expression level of the polypeptide or polynucleotide in a test sample; and the monoclonal or polyclonal antibodies against the polypeptides or active fragments thereof. The polypeptides of the present invention can be pharmaceutically used for treating the HIV infection, allergic disease, allograft rejection, diseases in brain and autoimmune diseases.Type: GrantFiled: June 6, 2007Date of Patent: December 16, 2008Inventors: Ying Wang, Yingmei Zhang, Wenling Han, Dalong Ma, Yanan Liu, Caihua Yin, Linjie Tian, Dan Li
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Patent number: 7450386Abstract: A phase-separated evaporator includes a boiler plate and a phase separation chamber that includes a housing, connected to the boiler plate, having a gas port and a liquid port; and a phase partitioner connected to interiors of the housing, dividing the phase-separated evaporator into a vapor directing compartment and a condensate directing compartment. The phase partitioner includes a partition panel and multiple feeding injectors extending from the partition panel, with the injector tips disposed immediately above the boiler plate. The returning condensate from a condenser enters from the liquid port into the condensate directing compartment and feeds onto the boiler plate through the feeding injectors; while the vapor generated in the vapor directing compartment exits from the gas port, without encountering the condensate.Type: GrantFiled: May 5, 2007Date of Patent: November 11, 2008Inventors: Paul Silverstein, Frederick K. Husher, Jee Shum
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Patent number: 7445480Abstract: A fused elbow terminator is disclosed which includes an elbow connector having a housing and a cable connector disposed within; and a fused pin connected to the cable connector. The fused pin includes an arc follower section, a fuse section and a cable interface section. Further disclosed is a stage-fused underground transformer loop system, which includes a series of transformers connected sequentially by a series of cables, and a series of fused elbow terminators connected to the inlets and outlets of the transformers. The fused elbow terminators are arranged in an order of decreasing the fuse capacity starting from the feed. A method of rapid diagnosis of a fault cable or a transformer failure using the stage-fused transformer loop system is also disclosed.Type: GrantFiled: September 23, 2006Date of Patent: November 4, 2008Inventor: Gregory P. Whyte
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Patent number: 7442371Abstract: Compositions, kits and methods are provided for promoting general health or for prevention or treatment of diseases by using novel recombinant fusion proteins of human serum albumin (HSA) and bioactive molecules. The bioactive molecules may be a protein or peptide having a biological function in vitro or in vivo, and preferably, having a therapeutic activity when administered to a human. By fusing the bioactive molecule to HSA, stability of the bioactive molecule in vivo can be improved and the therapeutic index increased due to reduced toxicity and longer-lasting therapeutic effects in vivo. In addition, manufacturing processes are provided for efficient, cost-effective production of these recombinant proteins in yeast.Type: GrantFiled: July 8, 2007Date of Patent: October 28, 2008Inventors: Zailin Yu, Yan Fu
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Patent number: 7431497Abstract: A dental x-ray film viewing device includes a film reader having a digital video camera and an image display screen connected to the video camera for displaying an enlarged digital image of the x-ray film using signals transmitted directly from the video camera. The film reader includes a film illumination station that has a back-lighted film seat. The film seat includes a translucent plate and a non-transparent film anchoring wafer having an opening complimentary to the x-ray film for seating the x-ray film, and blocking light in an area surrounding the x-ray film. The film reader has a video camera having lens thereof focusing on the film window, and the lens has a distortion at the full field less than 3%. The device provides a substantially enlarged high resolution and high contrast digital image as an accurate representation of the original x-ray film, without digital processing by a computer.Type: GrantFiled: September 26, 2006Date of Patent: October 7, 2008Inventors: James John Lucas, Fereidon Wolfgang Manssuri, Francis J. Lucas
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Patent number: 7365171Abstract: The present invention provides chemokine-like factor (CKLF) polypeptides with chemotactic and hematopoietic stimulating activities and polynucleotides encoding such polypeptides. Additionally, a method for producing such CKLF polypeptides by recombinant techniques is provided. Also provided are the antibodies and antagonists against such polypeptides. The present invention further disclose a drug compound comprising a therapeutically effective amount of such CKLF polypeptides as well as pharmaceutically acceptable excipients and carriers. Also disclosed are the uses of such CKLF polypeptides and polynucleotides in diagnostics or therapeutics to treat immunodeficiency, hematopoietic diseases and primary tumors.Type: GrantFiled: June 2, 2004Date of Patent: April 29, 2008Assignees: Beijing Medical University, Beijing Medical University United Biological Engineering CompanyInventors: Dalong Ma, Wenling Han, Yingme Zhang, Quansheng Song, Chunhui Di, Jiaqiang Huang, Jian Tang, Guanghui Chen
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Patent number: 7271008Abstract: The invention relates to a device and methods for determining the quality of reagents used in an assay process, particularly a multistep immunohistochemical assay. In particular, the device comprises a substrate with a plurality of compounds affixed to a substrate, where each compound is reactive with a reagent used in the assay.Type: GrantFiled: July 15, 2003Date of Patent: September 18, 2007Inventor: Alton David Floyd