Abstract: The present invention relates to conjugates for mediating a cell-specific, compartment-specific or membrane-specific to methods of active substances. The invention also relates to methods of preparing these conjugates as well as their use. The conjugates comprise:
a transport mediator for the cell membrane,
a cell-specific, compartment-specific or membrane-specific address protein or peptide, and
an active substance to be transported.
Type:
Grant
Filed:
July 2, 2002
Date of Patent:
November 23, 2004
Assignee:
Deutsche Krebsforschungszentrum Stiftung des Offentlichen
Rechts
Inventors:
Klaus Braun, Peter Peschke, Eckart Friedrich, Rüdiger Pipkorn, Waldemar Waldeck, Jürgen Debus