Abstract: A tamponade device for controlling post-partum hemorrhage includes an inner drain tube co-axially encircled by an inflatable balloon. The device is inserted into the uterine cavity, and the balloon is distended with a medium supplied with sufficient pressure and volume to apply even pressure along the surface of an interior uterine wall. With the application of such pressure, bleeding is stopped as evidenced by a cessation of blood draining from the inner drain tube. The inner tube includes a drainage port at an inserted end for draining blood and other fluids from the interior of the uterine cavity. An integral valve and medium insufflation and supply tubes operate to control inflation and deflation of the balloon. The supply tube co-axially encircles the drain tube to define a thin passageway between an inner surface of the supply tube and an outer surface of the drain tube. Perforations in the supply tube allow the medium to pass from this passageway in order to distend the balloon.

Abstract: The invention relates to therapeutic compositions and methods for treating and preventing infection by an immunodeficiency virus, particularly HIV infection, using chemokine proteins, nucleic acids and/or derivatives or analogs thereof.