Patents Represented by Attorney Yuan Chao
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Patent number: 6794366Abstract: Compounds of the formula or the 10,11-anhydro forms therefor, wherein Ra is H or OH; Rb is H or halogen; Rc is H or a protecting group; Rd is methyl; unsubstituted alkyl (3-10C); substituted alkyl (1-10C); substituted or unsubstituted alkenyl (2-10C) or substituted or unsubstituted alkynyl (2-10C); substituted or unsubstituted aryl (4-14C); substituted or unsubstituted arylalkyl (5-20C); substituted or unsubstituted arylalkenyl (5-20C); substituted or unsubstituted arylalkynyl (5-20C); substituted or unsubstituted amidoarylalkyl (5-20C); substituted or unsubstituted amidoarylalkenyl (5-20C); or substituted or unsubstituted amidoarylalkynyl (5-20C); Re is H or a protecting group or is mono- or disubstituted amino carbonyl; Rf is H; substituted or unsubstituted alkyl (1-10C); substituted or unsubstituted alkenyl (1-10C); substituted or unsubstituted alkynyl (1-10C); substituted or unsubstituted aryl (4-14C); substituted or unsubstituted arylalkyl (5-20C); or —ORf may be replaced bType: GrantFiled: April 17, 2002Date of Patent: September 21, 2004Assignee: Kosan Biosciences, Inc.Inventors: Daniel Chu, Gary Ashley
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Patent number: 6762168Abstract: The invention is directed towards antibacterial compounds. The invention concerns macrolide antibiotics useful as antiinfective agents.Type: GrantFiled: February 3, 2003Date of Patent: July 13, 2004Assignee: Kosan Biosciences, Inc.Inventor: Daniel T. W. Chu
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Patent number: 6750205Abstract: The present invention provides novel macrolide compounds of the formulas wherein: R is hydroxyl or methoxy; R1 is selected from the group consisting of hydrogen, hydroxyl, halide, NH2, OR9, where R9 is C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, aryl or heteroaryl and R10 and R11 are each independently hydrogen, C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, or aryl; R2 and R3 are each independently selected from the group consisting of hydrogen, C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, aryl, alkylaryl, alkenylaryl alkynylaryl or R2 and R3 together form a cycloalkyl or a cycloaryl moiety; R4 is hydrogen or methyl; R5 is hydrogen, hydroxyl, oxo, or together with R6 and the carbons to which they are attached form a cyclic carbonate; R6 is hydrogen, hydroxyl, OR12 where R12 is C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, or together with R5 and the carbons to which they are attached form a cyclic carbonate; R7 is methyl, C3-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynType: GrantFiled: April 7, 2003Date of Patent: June 15, 2004Assignee: Kosan Biosciences, Inc.Inventors: Gary Ashley, Mark Burlingame, Christopher Carreras, Daniel Santi
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Patent number: 6030681Abstract: A method of forming an article having a cermet layer on a porcelain substrate, via the steps of (a) providing a substrate made a porcelain comprising one or more crystalline oxide phases dispersed in a glassy matrix, the glassy matrix containing 0.25 to 45.0 weight % of a reducible metal oxide having a reduction potential of between -1.0 and +3.5 E.degree./V; and (b) heating the substrate in a reducing atmosphere to form on at least one surface of the substrate a layer of cermet comprising elemental metal which is a reduction product of the reducible metal oxide. The article may be used as a substrate for magnetic recording disks.Type: GrantFiled: July 10, 1997Date of Patent: February 29, 2000Assignee: Raychem CorporationInventors: Pawel Czubarow, Karin M. Kinsman, Amy S. Chu, Christian Weber, Ryan Dupon, Anthony Evans
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Patent number: 5994446Abstract: Gels of oil-extended methacrylate-alkylene-methacrylate (M-A-M) triblock copolymers having higher glass transition temperatures than known styrene-alkylene-styrene triblock gels. The preferred M-A-M triblocks for making the new gels have polymethylmethacrylate end blocks and butadiene or ethylene/butylene mid-block, and are synthesised by methods in the public domain (inter alia Shell EP-A-0431706). Includes gels of new triblocks having end blocks of higher alkyl (e.g. isobornyl) methacrylate homopolymer or copolymers. Mixed methyl- and higher alkyl-methacrylate end blocks are preferred to reduce gel-formation problems which may arise from solubility parameter of homo-isobornylmethacrylate end blocks being too close to that of extender oil. Includes gels of new multi- (preferably penta-) block copolymers including styrene (S) blocks, e.g. M-S-A-S-M.Type: GrantFiled: March 25, 1998Date of Patent: November 30, 1999Assignee: Raychem LimitedInventors: Hendrik Graulus, Noel Overbergh, John Hudson, Philip James Hammond, Jianming Yu, Anthony Perkins
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Patent number: 5979902Abstract: A cavity sealing article for use in a longitudinally extending cavity defined by cavity walls, the cavity having a cross-section within the cavity walls which is to be sealed at a predetermined location, comprises: (a) a driver comprising a crosslinked foamable polymer, the driver having a size, shape, and expansion ratio on foaming such that, when foamed within the cross-section of the cavity at the predetermined location, it substantially but incompletely occupies the cross-section of the cavity; and (b) a sealer comprising an uncrosslinked foamable polymer in intimate contact with the driver and surrounding the driver in the cross-section of the cavity, the sealer having a size, shape, and expansion ratio on foaming such that, when the cavity sealing article as a whole is foamed, the foamed sealer is forced into intimate and sealing contact with the cavity walls.Type: GrantFiled: September 8, 1997Date of Patent: November 9, 1999Assignee: Raychem CorporationInventors: Rong J. Chang, Keith Dawes
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Patent number: 5962553Abstract: Nanocomposites are made by melt-blending a melt processable polymer having a high melt processing temperature and an organophosphonium cation modified layered clay. Such modified layered clay is more stable at the higher temperatures encountered during the melt processing of such a melt processable polymer than the modified layered clays used in the prior art, enabling the preparation of the nanocomposite.Type: GrantFiled: September 3, 1996Date of Patent: October 5, 1999Assignee: Raychem CorporationInventor: Mark W. Ellsworth
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Patent number: 5952396Abstract: An elastomer has a modulus intermediate between that of a conventional rubber and a gel. The elastomer includes (a) between 20 and 45 parts by weight of a semicrystalline elastomer having between 1 and 15% crystallinity and (b) between 80 and 55 parts by weight of a compatible liquid elastomer having a number-average molecular weight of between 1,500 and 8,500. The elastomer's modulus is sufficiently high to enable it to be fabricated into handleable articles, but is sufficiently low so that it provides effective sealing of substrates it covers without the need for introducing a separate sealing material such as a mastic or adhesive.Type: GrantFiled: June 16, 1997Date of Patent: September 14, 1999Assignee: Raychem CorporationInventor: Rong Jong Chang
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Patent number: 5951912Abstract: A liquid crystal device has, as electrooptically active material, a liquid crystal composite including a containment medium, a liquid crystal composition dispersed in the containment medium, and an organotrialkoxysilane additive having the structure ##STR1## in which R.sub.1 and R.sub.2 are independently H, F, Cl, OCH.sub.3, OCH.sub.2 CH.sub.3, or a C.sub.1 to C.sub.8 alkyl, aryl or arylalkyl group; each R.sub.3 is independently a C.sub.1 to C.sub.8 alkyl, aryl, or arylalkyl; m is an integer from 0 to 4; and n is an integer from 2 to 4. The composite can be used for making liquid crystal displays having improved electro-optical properties, in particular a low operating field.Type: GrantFiled: July 31, 1998Date of Patent: September 14, 1999Assignee: Raychem CorporationInventor: Frank W. Mercer
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Patent number: 5951135Abstract: A system and method for projecting a color image is disclosed. The system includes a light dispersing system arranged in the path of a composite light beam for separating the composite light beam into spatially separated component beams, an image display arranged in the path of the component beams for producing modulated component beams, and a beam merging system producing a second light beam by merging the modulated component beams. The method includes producing spatially separated component light beams, directing the spatially separated component light beams to the surface of an image display, modulating display cells of the image display, and producing modulated component light beams.Type: GrantFiled: October 14, 1997Date of Patent: September 14, 1999Assignee: Raychem CorporationInventors: John E. Bigelow, Philip J. Jones
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Patent number: 5952612Abstract: A two part range-taking member for providing a seal around a substrate includes a mating pair of resilient components for enclosing the substrate and a co-operating pair of rigid components for urging the resilient components into conformity with the substrate. The member may provide an electrical stress cone for a power cable, for example with two such members being provided in a cable joint.Type: GrantFiled: May 8, 1997Date of Patent: September 14, 1999Assignee: Raychem LimitedInventors: Phillip Roland Winfield, David Ions, James Patrick Reed, Christian Kiermaier, Brian Clark
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Patent number: 5931474Abstract: A planar cavity sealing article comprises:(a) at least one driver comprising a crosslinked foamable polymer, and(b) a sealer comprising an uncrosslinked foamable polymer in intimate contact with the at least one driver and substantially surrounding the at least one driver in the plane of the article.Type: GrantFiled: February 23, 1998Date of Patent: August 3, 1999Assignee: Raychem CorporationInventors: Rong J. Chang, Keith Dawes
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Patent number: 5929138Abstract: A highly thermally conductive but yet highly conformable composition is made from gel filled with alumina. The use of .alpha.-alumina in which at least 10 weight % of the .alpha.-alumina particles have a particle size of at least 74 .mu.m makes possible the high filler levels needed to attain high thermal conductivity, without causing the decrease in elongation and softness normally associated with high filler levels. Further improvements are observed if the .alpha.-alumina and the gel (or precursor thereof) are mixed with a specific energy input of at least 10 Joule/g. The input of such specific energy has the effect making the resulting composition more conformable than it otherwise would be. The composition may be internally supported by a flexible matrix such as a fabric or open-celled foam.Type: GrantFiled: November 5, 1996Date of Patent: July 27, 1999Assignee: Raychem CorporationInventors: Frank W. Mercer, David P. Ching, Zbigniew Cichocki, Robert H. Reamey
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Patent number: 5924783Abstract: An optical projection system has a display cell that is configured to project a display image in response to light striking the display cell. The system has a light source that is configured to project a beam of light and a lens array that is positioned to intercept the beam and generate multiple beamlets of the beam. An aperture assembly is positioned to intercept the beamlets and is configured to selectively control which portions of the images contained in the beamlets strike the display cell.Type: GrantFiled: July 24, 1997Date of Patent: July 20, 1999Assignee: Raychem CorporationInventor: Philip J. Jones
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Patent number: 5900585Abstract: A 15 kv cable joint is enclosed within two half shells filled with sealant material. Displacement or thermal expansion of the sealant is accommodated by various configurations of stress cones that have apertures or surfaces that are flexible and arranged to maintain pressure on the sealant for example during thermal cycling of the joint.Type: GrantFiled: July 14, 1997Date of Patent: May 4, 1999Assignee: Raychem LimitedInventors: Phillip Roland Winfield, David Ions, James Patrick Reed, Christian Kiermaier, Brian Clark
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Patent number: 5886111Abstract: A silicone gel formulation is described having a Voland hardness of from about 6 to 20 grams, a tack of from about 17 to 35 grams, and a stress relaxation greater than 50%. The material is especially suitable for sealing the back end of connectors containing a multiple fine wires with gauges between about 14 gauge and 28 gauge. It is particularly suitable to seal the back end of an automotive connector subjected to a wide variety of harsh environmental conditions.Type: GrantFiled: March 24, 1997Date of Patent: March 23, 1999Assignee: Raychem CorporationInventors: Achilles Chiotis, Janusz Wojtowicz
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Patent number: 5883457Abstract: A touch sensor system, including a substrate, capable of propagating surface acoustic waves; and a reflective array formed on said substrate, said reflective array having a plurality of reflective elements, each reflective element reflecting a portion of an incident surface acoustic wave. The reflective array is formed of an organic matrix. The organic matrix is preferably chemically bonded to the substrate, and is preferably a thermoset resin. The resulting reflective arrays are preferably stable under changes in moisture between 0% and 60% RH at temperatures between about 0.degree.-50.degree. C. The organic matrix can also be used in a humidity or chemical sensor.Type: GrantFiled: April 24, 1997Date of Patent: March 16, 1999Assignee: Raychem CorporationInventors: James A. Rinde, Barry C. Mathews
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Patent number: 5863468Abstract: Calcined ceramic powder is made by blending a precursor powder with a form of carbon such as carbon black and heating the blend in an oxygenated atmosphere. The carbon acts as a separator, preventing coalescence of the percursor powder during the calcining process. The blend is characterized by the presence of interstitial spacing between the particles of the carbon powder and the precursor powder. The carbon is eventually oxidized to carbon dioxide and/or carbon monoxide and volatilizes as such, leaving behind the calcined ceramic powder. In a preferred embodiment, the heating is effected by microwave radiation. The carbon absorbs the microwave radiation, heating up the precursor powder and calcining it to form the ceramic powder. Once all the carbon has been oxidized, no more microwave radiation is absorbed, and the heating stops, making the process self-limiting.Type: GrantFiled: October 31, 1997Date of Patent: January 26, 1999Assignee: Raychem CorporationInventors: Pawel Czubarow, Mark W. Ellsworth, Karin M. Kinsman, Eugen L. Kurjatko, Andrew P. Washabaugh
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Patent number: 5856634Abstract: A recoverable article includes an inner resilient radially elastomeric tubular member 2 that is held in its expanded configuration by an outer relatively rigid shell 6. The interface between the member 2 and the shell 6 comprises a plurality of circumferentially-spaced parallel strips 4 coated onto the member 2. The strips 4 prevent the shell 6 from bonding to the member 2 in those regions. The shell 6 is castellated with its valleys 12 adjacent the edges of the strips 4. The lands 8 of the castellated shell 6 overlying the strips 4 can be peeled back to permit the resilient member 2 to recover towards its original configuration, for example around a power cable splice.Type: GrantFiled: March 19, 1997Date of Patent: January 5, 1999Assignee: Raychem CorporationInventor: Alan Borgstrom
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Patent number: 5849824Abstract: The invention provides for a thermoset or thermoplastic gel composition containing a polymer with anhydride groups along the polymer backbone at least at outset of the fabrication process and an extender fluid, optionally including thermally conductive fillers. The gel compositions are useful for sealing wires, vibration dampening, sporting goods, and toys.Type: GrantFiled: February 6, 1996Date of Patent: December 15, 1998Assignee: Raychem CorporationInventors: Frank Mercer, Hendrik Graulus