Abstract: The present invention is directed to novel substituted pyrroline compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder.
Type:
Grant
Filed:
May 8, 2007
Date of Patent:
July 20, 2010
Assignee:
Janssen Pharmaceutica, NV
Inventors:
Han-Cheng Zhang, Bruce E. Maryanoff, David F. McComsey, Kimberly White, Hong Ye, Leonard R. Hecker
Abstract: The present invention is directed to novel bicyclic triazolopyrimidine compounds of Formula (I) or a form thereof: wherein R1 and R2 are as defined herein, and their methods of preparation and use as ADP inhibitors.
Type:
Grant
Filed:
October 31, 2007
Date of Patent:
July 28, 2009
Assignee:
Janssen Pharmaceutica, N.V.
Inventors:
Han-Cheng Zhang, Bruce E. Maryanoff, Hong Ye, Cailin Chen