Patents Represented by Attorney, Agent or Law Firm Zoltan Kerekes
  • Hepatitis B vaccine
    Patent number: 5972346
    Abstract: A novel vaccine formulation is provided, comprising a hepatitis B component, particularly hepatitis B surface antigen, in combination with aluminum phosphate and 3-O-acylated monophosphoryl lipid A.
    Type: Grant
    Filed: October 27, 1997
    Date of Patent: October 26, 1999
    Assignee: SmithKline Beecham Biologicals S.A.
    Inventors: Pierre Hauser, Nathalie Marie-Josephe Claude Garcon, Pierre Desmons
  • Process for the preparation of a salt clavulanic acid
    Patent number: 5965728
    Abstract: A process for the preparation of a salt of clavulanic acid, wherein clavulanic acid in solution in a wholly or partly water-imiscible organic solvent is contacted in a region of high turbulence and/or shear stress, with a salt precursor compound to form a solution of the salt of clavulanic acid in an aqueous phase, then the organic solvent and aqueous phases are physically separated during a separation step, followed by a further processing step in which the said salt of clavulanic acid is isolated from solution as a solid.
    Type: Grant
    Filed: August 21, 1996
    Date of Patent: October 12, 1999
    Assignee: SmithKline Beecham PLC
    Inventors: Michael Alan Cook, Geoffrey Clive Webb
  • Fibrinogen receptor antagonists
    Patent number: 5900422
    Abstract: This invention relates to compounds of the formula: ##STR1## which are effective for inhibiting platelet aggregation, pharmaceutical compositions for effecting such activity, and a method for inhibiting platelet aggregation.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: May 4, 1999
    Assignee: SmithKline Beecham Corporation
    Inventor: Fadia El-Fehail Ali
  • Process for producing clavulanic acid
    Patent number: 5869299
    Abstract: A process for preparing clavulanic acid and other clavam derivatives using an enzyme system from Streptomyces, particularly S. Clavuligerus.
    Type: Grant
    Filed: August 25, 1995
    Date of Patent: February 9, 1999
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Keith Howard Baggaley, Neville Hubert Nicholson, Stephen William Elson, Jeffrey Edwards, Alison Jane Earl, William Henry Holms, David Michael Mousdale, Jack Edward Baldwin, Christopher Schofield
  • Fibrinogen receptor antagonists
    Patent number: 5795893
    Abstract: This invention relates to novel compounds which inhibit platelet aggregation, pharmaceutical compositions containing the compounds, and methods of using the compounds.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: August 18, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: William E. Bondinell, Thomas Wen-Fu Ku
  • Fibrinogen receptor antagonists
    Patent number: 5756519
    Abstract: The following invention relates to compounds which are effective for inhbiting platelet aggregation, pharmaceutical compositions for effecting such activity and a method for inhibiting platelet aggregation.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: May 26, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: William E. Bondinell, James M. Samanen
  • Vaccine composition containing adjuvants
    Patent number: 5750110
    Abstract: The present invention provides vaccine compositions comprising 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccines compositions are potent inducers of CTL and .gamma. IFN responses.
    Type: Grant
    Filed: February 17, 1995
    Date of Patent: May 12, 1998
    Assignee: SmithKline Beecham Biologicals, s.a
    Inventors: John Paul Prieels, Nathalie Marie-Josephe Claude Garcon-Johnson, Moncef Slaoui, Pietro Pala