Patents Assigned to 1 . . . Limited
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Patent number: 9339491Abstract: Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide or a pharmaceutically acceptable derivative thereof in the manufacture of a medicament for the treatment of acute exacerbations of chronic obstructive pulmonary disease. Treatment may involve a single dose of the active ingredient by oral administration.Type: GrantFiled: March 19, 2013Date of Patent: May 17, 2016Assignee: Mereo BioPharma 1 LimitedInventor: Paul Andrew Ford
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Patent number: 8350959Abstract: A camera lens actuation apparatus for driving motion of a camera lens supported on a support structure by a suspension system. The apparatus incorporates a subassembly comprising SMA wire connected to at least one mounting member which is mounted to the support structure. At least one pair of lengths of SMA wire are held in tension between the camera lens element and the support structure at respective acute angles to the optical axis applying a tensional force having a component along the optical axis. The lengths of SMA wire in the pair are held at angle as viewed along the optical axis. There may be plural pairs with a balanced arrangement in which the forces generated have no net component perpendicular to the optical axis and generate no net torque around any axis perpendicular to the optical axis. A control circuit controls heating of the SMA wire in response to a measure of its resistance.Type: GrantFiled: March 23, 2007Date of Patent: January 8, 2013Assignee: 1 . . . LimitedInventors: Richard Topliss, David Livingstone, Robert John Leedham
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Patent number: 7486004Abstract: A piezoelectric device comprising a continuous piezoelectric element (10) extending alternately back and forth to form a plurality of parallel, straight portions (14) arranged in a stack with intermediate linkage portions (15) at alternate ends of the straight portions (14). Each straight portion (14) is constructed and arranged with electrodes (12, 13) to bend, on activation, in the stacking direction in which the straight portions (14) are stacked with opposite curvature in two halves (16, 17) of the straight portion (14) to create displacement between the ends of the straight portion (14) in the stacking direction adding in series through the stack. The continuous nature of the piezoelectric element (10) eases manufacture. Devices with two types of construction are disclosed. Firstly, the continuous piezoelectric element (10) may have a bender construction such as a bimorph bender construction.Type: GrantFiled: October 28, 2002Date of Patent: February 3, 2009Assignee: 1 . . . LimitedInventors: James Allan, Gareth McKevitt, Mark Richard Shepherd, Richard Topliss
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Patent number: 7319641Abstract: The invention provides transducer arrays which are capable of outputting sound beams having a relatively constant width, and with minimal sidelobes, across a range of frequencies. This is achieved by utilising one or more digital signal modifiers within the signal path between the input sound signal and the array of transducers. Variable window functions are also disclosed.Type: GrantFiled: October 10, 2002Date of Patent: January 15, 2008Assignee: 1 . . . LimitedInventors: Angus Gavin Goudie, Paul Thomas Troughton, Anthony Hooley
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Patent number: 7302068Abstract: A loudspeaker for audible sound is described having a sound emitting element mounted onto a support structure and at least one actuator adapted to rotate said sound emitting element around a hinge section, wherein the actuator is made of piezoelectric material. In variants the actuator forms part of the hinge section and the loudspeaker is capable of generating vibrations through its support structure.Type: GrantFiled: June 19, 2002Date of Patent: November 27, 2007Assignee: 1 . . .LimitedInventors: Simon Andrew Longbottom, Andrew Matheson, Gareth McKevitt, Richard Topliss, Matthew John Pitts, Mark Richard Shepherd
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Patent number: 7224813Abstract: A loudspeaker comprising: a support, a sound-generating element mounted to the support for vibration to generate sound; and an electro-active device coupled between the support and the sound-generating element for vibrating the sound-generating element in response to an electrical signal. The electro-active device comprises a structure extending along a minor axis which extends in a curve around a major axis parallel to the vibration direction of the sound-generating element, the structure comprising successive electro-active portions arranged with electrodes to bend around the minor axis on activation in response to application of the electrical signal to the electrodes, and coupled together such that bending of successive portions causes concomitant rotation of adjacent portions around the minor axis adding incrementally along the minor axis, which rotation causes concomitant change of the axial length of the structure along the major axis.Type: GrantFiled: December 21, 2000Date of Patent: May 29, 2007Assignee: 1. . . LimitedInventors: Anthony Hooley, David Henry Pearce, Gareth McKevitt, Mark Richard Shepherd, James Allan, Simon Andrew Longbottom, Ursula Ruth Lenel
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Patent number: 7215788Abstract: A digital pulse-width-modulation (PWM) generator comprising: an n bit digital magnitude comparator having first and second n bit inputs and an output indicative of the relative values of the signals applied at the first and second inputs; a first n bit digital up/down counter having a count direction input coupled to receive a sign bit of a digital unary input signal, an n bit parallel binary count output connected to the first n bit input of the magnitude comparator, and a clock input; a second n bit counter having a clock input coupled to receive a constant rate clock signal and an n bit parallel binary count output connected to the second n bit input of the magnitude comparator; an AND gate having a first input coupled to receive the constant rate clock signal in frequency divided form and a second input coupled to receive a magnitude portion of the digital unary input signal, and further having an output connected to the clock input of the first counter; and wherein the comparator continually generates anType: GrantFiled: August 18, 2005Date of Patent: May 8, 2007Assignee: 1 . . . LimitedInventor: Anthony Hooley
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Patent number: 7166952Abstract: An equivalent to the spatial separation either side of a nominal median plane that is inherent in a bimorph (with one piezoelectric layer on one side, and the second on the other side of the plane) is attained by structurally shaping the cross-section of a simple, single piezoelectric layer (11) such that it has a multiplicity of piezoelectric portions arranged in two generally-planar groups one either side of a median plane, so that any dimension change undergone by a portion on one side of that plane will tend to bend the whole device in the opposite direction to the same sense dimension change undergone by a portion on the other side of that plane. The simple, single layer acts as though it were a bimorph if elongate and beam-like, bending along its length, one end moving up/down, or back/forth, relative to the other but with any need for an internal, electrode.Type: GrantFiled: September 26, 2002Date of Patent: January 23, 2007Assignee: 1. . . LimitedInventors: Richard Topliss, David Livingstone, Andrew Matheson, Gareth McKevitt, Mark Richard Shepherd, Anthony Hooley
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Patent number: 7161279Abstract: Electro-active actuators (310) and methods of manufacturing such actuators are described with such actuators (310) having a plurality of electro-active segments (311) arranged along a curved line with each segment (311) being essentially planar and coupled to adjacent segments (311) through joint sections (312) placed at opposite corners of the segment (311). The actuators (310) exhibit a displacement in a different direction than the direction of displacement of a segment when seen in isolation. They can be made from a continuous tape of material, preferably by die punching.Type: GrantFiled: October 30, 2002Date of Patent: January 9, 2007Assignee: 1. . . LimitedInventors: Richard Topliss, Neel Bhalsod, Mark Richard Shepherd
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Publication number: 20060191239Abstract: An automated process and apparatus for making a gastro-retentive device (10). The method includes the steps of providing a pouch assembly having an ingredient section within a membrane; folding the membrane to form a folded pouch assembly; inserting the folded pouch assembly into a first capsule section (20a) to form a pouch/first capsule assembly, and inserting the pouch/first capsule assembly into a second capsule section (20b). The process can further include the steps of providing a strip (32) of multiple pouch assemblies (18) and cutting a single pouch assembly from the strip (32). Also provided is an apparatus (38) for carrying out the above method which includes a tooling block (44) having a passageway (62) configured for slidable movement of the pouch assembly (18) therein, and a tooling pocket (60) extending from a top surface of the tooling block to the passageway and which receives the pouch assembly.Type: ApplicationFiled: July 30, 2004Publication date: August 31, 2006Applicant: Merrion Research 1 LimitedInventor: Jagathesan Moodley
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Patent number: 7069795Abstract: Various sensors use an electro-active device (11) electrically connected to a detector circuit. The electro-active device (11) comprises an electro-active structure in the form of a continuous electro-active member (12) curving in a helix around a minor axis (13) which is in itself curved for example in a helix around a major axis (14). On activation by relative displacement of the ends (16) of the device (11), the electro-active structure twists around the minor axis due to the fact that the minor axis (13) is curved. The continuous member (12) has a bender construction of a plurality of layers (21) and (22) including at least one layer of electro-active material so that concomitantly with the twisting the continuous member (12) bends generating an electrical signal detected by the detector circuit. The electro-active device (11) is advantageous as a sensing element in a sensor because it has a large displacement, high sensitivity and low compliance.Type: GrantFiled: June 19, 2002Date of Patent: July 4, 2006Assignee: 1...LimitedInventors: Gareth McKevitt, Anthony Hooley, David Henry Pearce, Ursula Ruth Lenel, Mark Richard Shepherd
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Patent number: 7068930Abstract: A camera (30) uses an electro-active device (11) to position a movable lens. The electro-active device (11) comprises an electro-active structure in the form of a continuous electro-active member (12) curving in a helix around a minor axis (13) which is in itself curved for example in a helix around a major axis (14). The continuous member (12) has a bender construction of a plurality of layers (21 and 22) including at least one layer of electro-active material so that it bends, on activation, around the minor axis (13). Concomitantly with the bending, the electro-active structure twists around the minor axis. Concomitantly with that twisting, relative displacement of the ends (16) of the device (11) occurs due to the combination of the twisting around the minor axis (13) and the fact that the minor axis (13) is curved. This structure of the electro-active device (11) is compact and provides for linear displacement, thereby making it suitable for positioning the lens of the camera (30).Type: GrantFiled: June 19, 2002Date of Patent: June 27, 2006Assignee: 1...LimitedInventors: Gareth McKevitt, Anthony Hooley, James Allan, David Henry Pearce, Ursula Ruth Lenel
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Publication number: 20050269906Abstract: An electro-active actuator having a bender construction comprising layers of electro-active material and electrode layers for activation of the electro-active material, the layers of electro-active material being shaped to extend continuously along at least one curved portion and at least one substantially flat portion arranged with electrical terminals for electrical connection to the electrode layers.Type: ApplicationFiled: November 11, 2003Publication date: December 8, 2005Applicant: 1... LimitedInventors: James Allan, David Pearce, Richard Topliss
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Patent number: 6967541Abstract: A digital pulse-width-modulation (PWM) generator comprising: an n bit digital magnitude comparator having first and second n bit inputs and an output indicative of the relative values of the signals applied at the first and second inputs; a first n bit digital up/down counter having a count direction input coupled to receive a sign bit of a digital unary input signal, an n bit parallel binary count output connected to the first n bit input of the magnitude comparator, and a clock input; a second n bit counter having a clock input coupled to receive a constant rate clock signal and an n bit parallel binary count output connected to the second n bit input of the magnitude comparator; an AND gate having a first input coupled to receive the constant rate clock signal in frequency divided form and a second input coupled to receive a magnitude portion of the digital unary input signal, and further having an output connected to the clock input of the first counter; and wherein the comparator continually generatesType: GrantFiled: May 2, 2001Date of Patent: November 22, 2005Assignee: 1 . . . LimitedInventor: Anthony Hooley
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Patent number: 6833656Abstract: The present invention relates to an electro-active device having an electro-active structure extending along a minor axis (36) which is curved, for example in a helix around a major axis (37). The electro-active structure comprises successive electro-active portions (35) extending around said minor axis and arranged with electrodes to bend, when activated, around the minor axis (36) such that bending of the successive portions (35) is concomitant with rotation of the electro-active structure about the minor axis (36) adding incrementally along the minor axis (36). The electro-active structure generates displacement out of the local plane in which the minor axis is curved. The electra-active structure may be continuous electro-active member (35) extending along and curving around the minor axis (35), for example helically to form a helical helix. Alternatively, the electro-active structure may be a plurality of discrete elements (211) connected together.Type: GrantFiled: October 10, 2002Date of Patent: December 21, 2004Assignee: 1 . . . LimitedInventors: Anthony Hooley, David Henry Pearce, Ursula Ruth Lenel, Gareth McKevitt, Mark Richard Shepherd
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Publication number: 20040101150Abstract: A unimorph or bimorph piezoelectric ‘bender’ formed into a flat- (or edge-) wound helix (50,54,55) wherein there is an additional laminate layer of a piezo-resistive material (609,709) the function of which is for sensing and responding to the actual deflection of the bender device. It also discloses a method for making this type of device by co-extrusion of a sinterable paste of the appropriate composition.Type: ApplicationFiled: November 19, 2003Publication date: May 27, 2004Applicant: 1...LimitedInventors: Anthony Hooley, David Henry Pearce
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Patent number: 6677034Abstract: In its first aspect the invention provides an electromechanical acoustic transducer (5) which is resistively terminated at the rear with a closely-coupled sound absorber (7) made from an aerogel with good acoustic absorption at low frequencies. The invention also provides an aerogel suitable for this use and which is a conglomerate of small particles packed so that there are spaces left therebetween to allow the passage of sound. Moreover, the invention provides an aerogel suitable for this use and comprised of multiple layers (17a etc.) of materials of graded properties, or comprised of material of continuously varying properties throughout the thickness of the absorbing structure, in the principal direction of sound from the source.Type: GrantFiled: March 6, 2000Date of Patent: January 13, 2004Assignee: 1 . . . LimitedInventors: Anthony Hooley, David Henry Pearce, Luc Forest
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Patent number: 6483208Abstract: In an electric linear motor, the stator coils are arranged in a line, and the field they produce advances along that line driving the translator along with it. None of the known linear motors can provide all of very high speed, low force, long travel, high linearity and very low moving mass; the present invention proposes an answer in the form of a mechanism that applies motive, displacing force not primarily in the direction along with translator movement is desired but instead approximately at right angles to that direction, the translator being “squeezed” out like a cherry pip squeezed between finger and thumb.Type: GrantFiled: August 28, 2001Date of Patent: November 19, 2002Assignee: 1 . . . LimitedInventor: Anthony Hooley
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Patent number: 6425384Abstract: A diagnostic/control device for fuel injected internal combustion engines comprising a control system (14) connectable via leads (16) to the fuel injectors (10) after disconnection therefrom of an engine management computer (11), the latter being connected directly (at 18) to the control system (14). An oxygen sensor (13) is connected (at 17) to the control system (14) whereby the latter is connected between the engine management computer (11) and the fuel injectors (10) and can be operated in closed circuit or open circuit mode to control the injectors directly when required independently of the engine management computer (11).Type: GrantFiled: May 24, 2000Date of Patent: July 30, 2002Assignee: Factor 1 LimitedInventors: Mark Vincent Howarth, Edward Christopher Zyla
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Patent number: 6373955Abstract: A loudspeaker has a digital input signal port connected to a digital interpolator to increase the effective sampling rate whose output is fed to a signal delay and magnitude detector after which the short-term dynamic range of the input signal is possibly reduced before application of a unary encoder which encodes the digital input signal into a plurality of unary signals which are then differentially delayed and pulse shaped before application to a plurality of substantially identical acoustic transducers via transducer drivers whose average power drive levels may be controlled by signals derived from the magnitude detector and from a human operator to alter the sound volume produced.Type: GrantFiled: September 30, 1997Date of Patent: April 16, 2002Assignee: 1... LimitedInventor: Anthony Hooley