Patents Assigned to 20/20 GeneSystems
  • Publication number: 20030180961
    Abstract: Provided herein are methods for preliminary analysis of suspect samples, which can be used in triaging possible contaminated sites (e.g., sites contaminated or thought to be contaminated by biowarfare agents). In some embodiments, the methods involve testing for the presence of protein in the suspect sample; optionally, the sample can also be tested for the presence of sugar, and/or for pH determination. Specific embodiment methods are carried out in tubes or other reaction vessels, others are carried out in a pad format, and still others are carried out in a test strip format. Kits for carrying out the described methods are also provided.
    Type: Application
    Filed: February 21, 2003
    Publication date: September 25, 2003
    Applicant: 20/20 GeneSystems, Inc.
    Inventors: Vladimir Knezevic, Dan-Paul Hartmann, Jonathan Cohen, Elizabeth Marcus
  • Patent number: 6602661
    Abstract: The present invention is directed to a device and a method for detecting biomolecules in a tissue section or other two-dimensional sample by creating “carbon copies” of the biomolecules eluted from the sample and visualizing the biomolecules on the copies using antibodies or DNA probes having specific affinity for the biomolecules of interest. Thin membranes in a stacked or layered configuration are applied to the sample, such as a tissue section, and reagents and reaction conditions are provided so that the biomolecules are eluted from the sample and transferred onto each of the stacked membranes thereby producing multiple replicas of the biomolecular content of the sample.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: August 5, 2003
    Assignees: 20/20 GeneSystems, Inc., The United States of America as represented by the Department of Health and Human Services
    Inventors: Vladimir Knezevic, Michael R. Emmert-Buck