Abstract: One or more preferred embodiments facilitate use of patient panomics indications to select treatments that will provide optimal results. One or more preferred embodiments relate to a practical ontology for the panomics domain that is utilized to support use of patient panomics indications. In accordance with one or more preferred implementations, a cancer panomics ontology facilitates replacement of traditional cancer stratification by organs (e.g. lung, breast, liver cancer) with cancer stratification by tumor biomarkers (e.g. HER2 mutations). In accordance with one or more preferred implementations, a panomic ontology is utilized to facilitate functionality of a precision medical system.