Abstract: Compositions, methods and delivery devices (e.g., pre-filled syringes) for controlling bleeding during surgical procedures are provided, wherein the compositions are characterized as having an aqueous formulation that is capable of adopting a gelled state upon contact with bodily fluids and/or blood of a patient (i.e., physiological conditions).
Abstract: In various aspects the present inventions provide compositions and methods for treatment of cardiac conditions. In various embodiments, the present inventions provide methods for treating a cardiac condition comprising the step of administering in a therapeutically effective amount the substantially cell free solution of an amphiphilic self-assembling peptide to a site of cardiac tissue that has been injured due to one or more of atrial fibrillation, acute myocardial infarction; valve disease, pericardial disease, congenital heart disease, congestive heart failure, and embolism.
Abstract: In various aspects the present inventions provide compositions and methods for treatment of cardiac conditions. In various embodiments, the present inventions provide methods for treating a cardiac condition comprising the step of administering in a therapeutically effective amount the substantially cell free solution of an amphiphilic self-assembling peptide to a site of cardiac tissue that has been injured due to one or more of atrial fibrillation, acute myocardial infarction; valve disease, pericardial disease, congenital heart disease, congestive heart failure, and embolism.