Abstract: A negative pressure therapy device for inducing negative pressure in a urinary tract includes an inflow member and an outflow member. The inflow member includes (i) a proximal portion, (ii) a retention portion configured to be deployed within a renal pelvis of the urinary tract comprising a drainage hole leading to the inflow lumen, and (iii) an intermediate portion between the proximal portion and the retention portion. The intermediate portion is configured to extend through a portion of the kidney to the renal pelvis. The outflow member includes (i) a proximal portion, (ii) a distal end configured to be positioned in the ureter or bladder, and (iii) at least one intermediate portion extending from the proximal portion to the distal end.

Abstract: A system for removing fluid from a urinary tract includes at least one sensor configured to detect signal(s) representative of pulmonary artery pressure and communicate signal(s) representative of the pulmonary artery pressure and a controller. The controller is configured to: receive and process the signal(s) from the at least one sensor to determine if the pulmonary artery pressure is above, below, or at a predetermined value; and provide a control signal, determined at least in part from the pulmonary artery pressure signal(s) received from the at least one sensor, to a negative pressure source to apply negative pressure to a urinary catheter to remove fluid from a urinary tract when the pulmonary artery pressure is above the predetermined value and to cease applying negative pressure when the pulmonary artery pressure is at or below the predetermined value.